American Journal of Life Sciences
Volume 3, Issue 2, April 2015, Pages: 71-75
Received: Jan. 24, 2015;
Accepted: Feb. 8, 2015;
Published: Feb. 25, 2015
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Anas Rashid, Hamdard Institute of Pharmaceutical Sciences (HIPS), Hamdard University Islamabad Campus (HUIC), Islamabad, Pakistan
Usamah Rashid Qureshi, Department of Business Studies, Faculty of Economics and Business Studies, Pakistan Institute of Development Economics (PIDE), Quaid-i-Azam University Campus, Islamabad, Pakistan
Aiman Rashid, Department of Design and Manufacturing Engineering, School of Mechanical and Manufacturing Engineering (SMME), National University of Sciences and Technology (NUST), NUST Campus, Islamabad, Pakistan
Hamza Rashid, Department of Computer Sciences, Faculty of Natural Sciences, Quaid-i-Azam University (QAU), Islamabad, Pakistan
Clinical microbiologist are facing challenge to defeat the bacterial infections like Methicillin Resistant Staphylococcus aureus (MRSA) in humans; due to unique resistance in bacterial strain. There are limited medication options left to conquer this deadly toxicities, if holistic approach is ignored. Also the linked complications and consequences of infections may increase beyond threshold levels; if exercise only a single array of drug therapy. This empirical study aims to create synergy by adopting an integrated drug therapy approach for optimum treatment. This research article is based on primary microbial data collection (from sputum, urine and blood) in hospital; where the experiment focuses to investigate the highest risk vulnerable area. The result depicts high prevalence of MRSA in blood sample (50 %) among in-door patients of age above 50. The preventive and curative measures are discussed along with alternative multiple array of medication with prudent selection to achieve targeted and optimum outcome.
Usamah Rashid Qureshi,
Combating MRSA in Pakistan: An Integrated Drug Therapy Approach, American Journal of Life Sciences.
Vol. 3, No. 2,
2015, pp. 71-75.
McKenna, M. (2010). Superbug: The Fatal Menace of MRSA. Ed., pp. 288, Simon and Schuster, New York.
Morello, J., Granato, P. and Morton, V. (2013). Lab Manual and Workbook in Microbiology: Applications to Patient care. 11th Ed., pp. 336, McGraw-Hill Education, New York.
Weigelt, J.A. (2014). MRSA. 2nd Ed., pp. 240, CRC Press, London.
Hektoen, L., Larsen, S., Ødegaard, S.A. and Løken, T. (2004). Comparison of Homeopathy, Placebo and Antibiotic Treatment of Clinical Mastitis in Dairy Cows – Methodological Issues and Results from a Randomized-clinical Trial. Journal of Veterinary Medicine Series A, 51(9-10): 439-446.
Hogg, S. (2013). Essential Microbiology. 2nd Ed., pp. 526, Wiley-Blackwell, Chichester, West Sussex.
Cappuccino, J. and Sherman, N. (2013). Microbiology: A Laboratory Manual. 10th Ed., pp. 560, Pearson - Benjamin Cummings, Boston.
Westh, H., Zinn, C.S., Rosdahl, V.T. and Sarisa Study, G. (2004). An International Multicenter Study of Antimicrobial Consumption and Resistance in Staphylococcus aureus Isolates from 15 Hospitals in 14 Countries. Microbial Drug Resistance, 10(2): 169-176.
Brown, A. and Smith, H. (2014). Benson's Microbiological Applications: Laboratory Manual in General Microbiology, Complete Version. 13th Ed., pp. 576, McGraw-Hill Education, New York.
Smith, T.L., Pearson, M.L., Wilcox, K.R., Cruz, C., Lancaster, M.V., Robinson-Dunn, B., Tenover, F.C., Zervos, M.J., Band, J.D., White, E. and Jarvis, W.R. (1999). Emergence of Vancomycin Resistance in Staphylococcus aureus. New England Journal of Medicine, 340(7): 493-501.
Tille, P.M. (2013). Bailey & Scott's Diagnostic Microbiology. 13th Ed., pp. 1056, Elsevier, St. Louis.
Aureden, K., Arias, K., Burns, L.A., Creen, C., Hickok, J., Moody, J., Oriola, S. and Risa, K. (2010). Guide to the Elimination of Methicillin-Resistant Staphylococcus aureus (MRSA) Transmission in Hospital Settings. 2nd Ed., pp. 65, APIC, Washington, DC.
Pruthi, V. and Cameotra, S.S. (1997). Rapid identification of biosurfactant-producing bacterial strains using a cell surface hydrophobicity technique. Biotechnology Techniques, 11(9): 671-674.
Ziakas, P.D., Zacharioudakis, I.M., Zervou, F.N. and Mylonakis, E. (2015). Methicillin-Resistant Staphylococcus aureus Prevention Strategies in the ICU: A Clinical Decision Analysis. Critical Care Medicine, 43(2): 382-393.
Chan, B.C.-L., Bik-San Lau, C., Jolivalt, C., Lui, S.-L., Ganem-Elbaz, C., Paris, J.-M., Litaudon, M., Fung, K.-P., Leung, P.-C. and Ip, M. (2011). Chinese Medicinal Herbs Against Antibiotic resistant Bacterial Pathogen. Science against Microbial Pathogens: Communicating Current Research and Technological Advances, 2(3): 773-781.
Whitmont, R.D. (2011). MRSA and CAM. http://www.homeopathicmd.com/2011/04/mrsa-and-cam/. Accessed 08 October 2014.