American Journal of Life Sciences

| Peer-Reviewed |

Physiological Health Criteria for Pyrethriod Insecticide: A Pre-test Study with Guinea Pigs

Received: 06 May 2017    Accepted: 18 May 2017    Published: 07 July 2017
Views:       Downloads:

Share This Article

Abstract

A study of the use of lambdacyhalothrin (pyrethroid insecticide) treated curtains, mats and blankets as an alternative strategy to insecticide treated bed net for malaria control, was undertaken from 2003 to 2004 in Oruku – a sub-urban community in Nkanu East Local Government, very near Enugu in Enugu state of Nigeria. Prior to the village study, a pre-test study (safety testing) was done using Guinea pigs from January 2003 to April 2003. It was carried out inside zoological garden University of Nigeria, Nsukka. The objective of the pre-test study was to ascertain the effect of Lambdacyhalothrin on physiology of Guinea pigs before using it in human habitation (Guinea pig has physiology akin to human). The Guinea pigs were maintained in animal cages and acclimatized for four weeks before the introduction of the insecticide. Effect of the insecticide on vital physiological parameters of the Guinea pigs were measured weekly for 15 weeks. The data were analyzed using chi-square, ratio (fscore), correlation coefficient ‘r’ and coefficient of determination (r2). Result showed that Lambdacyhalothrin at 0.001mg/l to 0.050mg/l concentrations were well tolerated by the guinea pigs and was thought to be safe for use in human environment/habitation with no disruption of physiological activities.

DOI 10.11648/j.ajls.20170504.11
Published in American Journal of Life Sciences (Volume 5, Issue 4, August 2017)
Page(s) 97-102
Creative Commons

This is an Open Access article, distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution and reproduction in any medium or format, provided the original work is properly cited.

Copyright

Copyright © The Author(s), 2024. Published by Science Publishing Group

Keywords

Guinea Pig, Pyrethriod Insecticide, Physiological Similarities, Malaria Control

References
[1] Costello, J. (2011). “The great zoo’s who”. Irish Independent. > http://www.independent. i.e. / lifestyle/the-great-zoos-who. Html< Date accessed: April 9, 2012.
[2] Gorden, P. (1997). “Non- insulin dependent diabetes- the past, present and future”. Annual Academic medical Sin gap, 26(3): 326-330.
[3] Greenwood, B. M. (1999). What can the resident of malaria endemic countries do to protect themselves against malaria. London School of Hygiene and Tropical Medicine,
[4] Greenwood, B. M. (1997). What’s new in malaria control? Annual of Tropical Medicine and Parasitology, 91: 523 – 531.
[5] LVMA (2000). Biology of Guinea pig. Louisiana Veterinary Medical Association. 4p> www.lvma.org/pig.html< Date accessed: February 6, 2000.
[6] Malaria Consortium. (2016). Malaria consortium disease control, better health. http://www.malariaconsortium.org/pages/109.htm.
[7] Mock, M. and Fouet, A. (2001). “Anthrax”. Annual Review of Microbiology, 55: 647-67.
[8] Mutero, C. M., Mbogo, C., Mwangangi, J., Imbahale, S., Kibe, L., Orindi, B., Girma, M., Njui, A., Lwande, W., Affognon, H., Gichuki, C., and Mukabana1, W. R. (2015). An Assessment of Participatory Integrated Vector Management for Malaria Control in Kenya. Environmental Health Perspectives, volume 123( 11 ): 1145 -1151.
[9] Okoh, F. N., Odikamnoro, O. O., Uhuo, C. A., Okereke, C. N., Azi, S. O. and Ogidi, E. D. (2014). Epidemiology of malaria among children aged 1 to 15 years in South East Nigeria. Jounal of Public Health and Epidemiolgy. Academic Journals, volume 6(11): 390-397.
[10] Scollard, D. M., Adams, L. B., Gillis, T., Krahenbuhl, J. L., Truman, R. W., and Williams, D. L. (2006). “The continuing challenges of leprosy”. Clinical Microbiology Review, 19(2): 338-81 http://www.pubmedcentral.gov/articlerender.fcgi.
[11] Trull, F. L, Rich, B. A. (1999). More Regulation of Rodents Science. PubMed 284 (5419): 1463.
[12] UAR. (2012). Guinea pig in medical research, A-Z of Different Animals Used. Understanding Animals Research. >www.understandinganimalresearch.org.uk.html<Date accessed: April 9, 2012.
[13] Walgate, R. (1981). “Armadillos fish leprosy”. Nature, 291(5816): 527 http://www.nebi.nih.gov/pubmed/7242665.
[14] Windholz, G. (1987). “Pavlov as a psychologist. A reappraisal” Pavlov Journal of Biological Science, 22(3): 103-112. http://www.ncbi.nlm.nih.gov/pubmed.
[15] World Health Organization.(2014). World malaria report, 2014, http://www.who.int/malaria/WMR014.
[16] World Health Organization.(2013). World malaria report, 2013, http://www.who.int/malaria/WMR0143.
[17] World Health Organization. (2006). Global malaria programme: Use of indoor residual spraying for scaling up global malaria control and elimination. http://apps.who.int/iris/bitstream/10665/69386/1/WHO_HTM_MAL_2006.1112_eng.pdf.
[18] World Health Organization. (2005). World health report, 2005. Make every mother and child count. http://www.who.int/whr/2005/en/.
Author Information
  • Department of Biological Sciences, Evangel University Akaeze, Abakaliki, Nigeria

  • Department of Applied Biology, Ebonyi State University Abakaliki, Abakaliki, Nigeria

  • Department of Zoology and Environmental Biology, University of Nigeria, Enugu, Nigeria

  • Department of Zoology and Environmental Biology, University of Nigeria, Enugu, Nigeria

  • Department of Zoology and Environmental Biology, University of Nigeria, Enugu, Nigeria

Cite This Article
  • APA Style

    Felicia Ngozi Okoh, Oliver Onyemaeze Odikamnoro, Joy Ihuoma Nzei, Ikem Chris Okoye, Fabian Chukwuzubelu Okafor. (2017). Physiological Health Criteria for Pyrethriod Insecticide: A Pre-test Study with Guinea Pigs. American Journal of Life Sciences, 5(4), 97-102. https://doi.org/10.11648/j.ajls.20170504.11

    Copy | Download

    ACS Style

    Felicia Ngozi Okoh; Oliver Onyemaeze Odikamnoro; Joy Ihuoma Nzei; Ikem Chris Okoye; Fabian Chukwuzubelu Okafor. Physiological Health Criteria for Pyrethriod Insecticide: A Pre-test Study with Guinea Pigs. Am. J. Life Sci. 2017, 5(4), 97-102. doi: 10.11648/j.ajls.20170504.11

    Copy | Download

    AMA Style

    Felicia Ngozi Okoh, Oliver Onyemaeze Odikamnoro, Joy Ihuoma Nzei, Ikem Chris Okoye, Fabian Chukwuzubelu Okafor. Physiological Health Criteria for Pyrethriod Insecticide: A Pre-test Study with Guinea Pigs. Am J Life Sci. 2017;5(4):97-102. doi: 10.11648/j.ajls.20170504.11

    Copy | Download

  • @article{10.11648/j.ajls.20170504.11,
      author = {Felicia Ngozi Okoh and Oliver Onyemaeze Odikamnoro and Joy Ihuoma Nzei and Ikem Chris Okoye and Fabian Chukwuzubelu Okafor},
      title = {Physiological Health Criteria for Pyrethriod Insecticide: A Pre-test Study with Guinea Pigs},
      journal = {American Journal of Life Sciences},
      volume = {5},
      number = {4},
      pages = {97-102},
      doi = {10.11648/j.ajls.20170504.11},
      url = {https://doi.org/10.11648/j.ajls.20170504.11},
      eprint = {https://download.sciencepg.com/pdf/10.11648.j.ajls.20170504.11},
      abstract = {A study of the use of lambdacyhalothrin (pyrethroid insecticide) treated curtains, mats and blankets as an alternative strategy to insecticide treated bed net for malaria control, was undertaken from 2003 to 2004 in Oruku – a sub-urban community in Nkanu East Local Government, very near Enugu in Enugu state of Nigeria. Prior to the village study, a pre-test study (safety testing) was done using Guinea pigs from January 2003 to April 2003. It was carried out inside zoological garden University of Nigeria, Nsukka. The objective of the pre-test study was to ascertain the effect of Lambdacyhalothrin on physiology of Guinea pigs before using it in human habitation (Guinea pig has physiology akin to human). The Guinea pigs were maintained in animal cages and acclimatized for four weeks before the introduction of the insecticide. Effect of the insecticide on vital physiological parameters of the Guinea pigs were measured weekly for 15 weeks. The data were analyzed using chi-square, ratio (fscore), correlation coefficient ‘r’ and coefficient of determination (r2). Result showed that Lambdacyhalothrin at 0.001mg/l to 0.050mg/l concentrations were well tolerated by the guinea pigs and was thought to be safe for use in human environment/habitation with no disruption of physiological activities.},
     year = {2017}
    }
    

    Copy | Download

  • TY  - JOUR
    T1  - Physiological Health Criteria for Pyrethriod Insecticide: A Pre-test Study with Guinea Pigs
    AU  - Felicia Ngozi Okoh
    AU  - Oliver Onyemaeze Odikamnoro
    AU  - Joy Ihuoma Nzei
    AU  - Ikem Chris Okoye
    AU  - Fabian Chukwuzubelu Okafor
    Y1  - 2017/07/07
    PY  - 2017
    N1  - https://doi.org/10.11648/j.ajls.20170504.11
    DO  - 10.11648/j.ajls.20170504.11
    T2  - American Journal of Life Sciences
    JF  - American Journal of Life Sciences
    JO  - American Journal of Life Sciences
    SP  - 97
    EP  - 102
    PB  - Science Publishing Group
    SN  - 2328-5737
    UR  - https://doi.org/10.11648/j.ajls.20170504.11
    AB  - A study of the use of lambdacyhalothrin (pyrethroid insecticide) treated curtains, mats and blankets as an alternative strategy to insecticide treated bed net for malaria control, was undertaken from 2003 to 2004 in Oruku – a sub-urban community in Nkanu East Local Government, very near Enugu in Enugu state of Nigeria. Prior to the village study, a pre-test study (safety testing) was done using Guinea pigs from January 2003 to April 2003. It was carried out inside zoological garden University of Nigeria, Nsukka. The objective of the pre-test study was to ascertain the effect of Lambdacyhalothrin on physiology of Guinea pigs before using it in human habitation (Guinea pig has physiology akin to human). The Guinea pigs were maintained in animal cages and acclimatized for four weeks before the introduction of the insecticide. Effect of the insecticide on vital physiological parameters of the Guinea pigs were measured weekly for 15 weeks. The data were analyzed using chi-square, ratio (fscore), correlation coefficient ‘r’ and coefficient of determination (r2). Result showed that Lambdacyhalothrin at 0.001mg/l to 0.050mg/l concentrations were well tolerated by the guinea pigs and was thought to be safe for use in human environment/habitation with no disruption of physiological activities.
    VL  - 5
    IS  - 4
    ER  - 

    Copy | Download

  • Sections