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Analysis of the Levels of Endothelin, Homocysteine and Blood Lipid in Patients with Clinical and Subclinical Hyperthyroidism

Received: 26 February 2019    Accepted:     Published: 28 April 2019
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Abstract

[Objective] To discuss the changes of endothelin (ET), homocysteine (Hcy) and blood lipids levels in patients with hyperthyroidism and subclinical hyperthyroidism, and to explore their clinical significance. [Methods] The authors choose 251 cases of hyperthyroidism, 242 cases of subclinical hyperthyroidism and 130 cases of the control group to test ET, Hcy, TC, TG, HDL, LDL and LPa. [Results] The level of ET of Hyperthyroidism group is higher than subclinical hyperthyroidism group and the control group. The level of ET of subclinical Hyperthyroidism group is higher than the control group(P<0.05). The level of Hcy of Hyperthyroidism group and subclinical Hyperthyroidism group was lower than the control group(P<0.05). The level of TG, TC, LDL, LPa of subclinical Hyperthyroidism group are lower than the control group(P<0.05). The level of TG, TC, HDL, LDL, LPa of Hyperthyroidism group are lower than the control group and subclinical hyperthyroidism group (P<0.05). [Conclusions] All of ET, Hcy and lipids participate in the occurrence and development process of hyperthyroidism and subclinical hyperthyroidism. Monitoring the change of related indexes is helpful to predict the transformation of subclinical hyperthyroidism to hyperthyroidism and the occurrence of cardiovascular disease.

Published in American Journal of Life Sciences (Volume 7, Issue 1)
DOI 10.11648/j.ajls.20190701.15
Page(s) 27-30
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This is an Open Access article, distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution and reproduction in any medium or format, provided the original work is properly cited.

Copyright

Copyright © The Author(s), 2024. Published by Science Publishing Group

Keywords

Hyperthyroidism, Subclinical Hyperthyroidism, Hcy, ET, Blood Lipids

References
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  • APA Style

    Xu Qian, Zhang Jing-yu, Li Hong-yan, Hou Jian-zhang. (2019). Analysis of the Levels of Endothelin, Homocysteine and Blood Lipid in Patients with Clinical and Subclinical Hyperthyroidism. American Journal of Life Sciences, 7(1), 27-30. https://doi.org/10.11648/j.ajls.20190701.15

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    ACS Style

    Xu Qian; Zhang Jing-yu; Li Hong-yan; Hou Jian-zhang. Analysis of the Levels of Endothelin, Homocysteine and Blood Lipid in Patients with Clinical and Subclinical Hyperthyroidism. Am. J. Life Sci. 2019, 7(1), 27-30. doi: 10.11648/j.ajls.20190701.15

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    AMA Style

    Xu Qian, Zhang Jing-yu, Li Hong-yan, Hou Jian-zhang. Analysis of the Levels of Endothelin, Homocysteine and Blood Lipid in Patients with Clinical and Subclinical Hyperthyroidism. Am J Life Sci. 2019;7(1):27-30. doi: 10.11648/j.ajls.20190701.15

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  • @article{10.11648/j.ajls.20190701.15,
      author = {Xu Qian and Zhang Jing-yu and Li Hong-yan and Hou Jian-zhang},
      title = {Analysis of the Levels of Endothelin, Homocysteine and Blood Lipid in Patients with Clinical and Subclinical Hyperthyroidism},
      journal = {American Journal of Life Sciences},
      volume = {7},
      number = {1},
      pages = {27-30},
      doi = {10.11648/j.ajls.20190701.15},
      url = {https://doi.org/10.11648/j.ajls.20190701.15},
      eprint = {https://article.sciencepublishinggroup.com/pdf/10.11648.j.ajls.20190701.15},
      abstract = {[Objective] To discuss the changes of endothelin (ET), homocysteine (Hcy) and blood lipids levels in patients with hyperthyroidism and subclinical hyperthyroidism, and to explore their clinical significance. [Methods] The authors choose 251 cases of hyperthyroidism, 242 cases of subclinical hyperthyroidism and 130 cases of the control group to test ET, Hcy, TC, TG, HDL, LDL and LPa. [Results] The level of ET of Hyperthyroidism group is higher than subclinical hyperthyroidism group and the control group. The level of ET of subclinical Hyperthyroidism group is higher than the control group(P<0.05). The level of Hcy of Hyperthyroidism group and subclinical Hyperthyroidism group was lower than the control group(P<0.05). The level of TG, TC, LDL, LPa of subclinical Hyperthyroidism group are lower than the control group(P<0.05). The level of TG, TC, HDL, LDL, LPa of Hyperthyroidism group are lower than the control group and subclinical hyperthyroidism group (P<0.05). [Conclusions] All of ET, Hcy and lipids participate in the occurrence and development process of hyperthyroidism and subclinical hyperthyroidism. Monitoring the change of related indexes is helpful to predict the transformation of subclinical hyperthyroidism to hyperthyroidism and the occurrence of cardiovascular disease.},
     year = {2019}
    }
    

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  • TY  - JOUR
    T1  - Analysis of the Levels of Endothelin, Homocysteine and Blood Lipid in Patients with Clinical and Subclinical Hyperthyroidism
    AU  - Xu Qian
    AU  - Zhang Jing-yu
    AU  - Li Hong-yan
    AU  - Hou Jian-zhang
    Y1  - 2019/04/28
    PY  - 2019
    N1  - https://doi.org/10.11648/j.ajls.20190701.15
    DO  - 10.11648/j.ajls.20190701.15
    T2  - American Journal of Life Sciences
    JF  - American Journal of Life Sciences
    JO  - American Journal of Life Sciences
    SP  - 27
    EP  - 30
    PB  - Science Publishing Group
    SN  - 2328-5737
    UR  - https://doi.org/10.11648/j.ajls.20190701.15
    AB  - [Objective] To discuss the changes of endothelin (ET), homocysteine (Hcy) and blood lipids levels in patients with hyperthyroidism and subclinical hyperthyroidism, and to explore their clinical significance. [Methods] The authors choose 251 cases of hyperthyroidism, 242 cases of subclinical hyperthyroidism and 130 cases of the control group to test ET, Hcy, TC, TG, HDL, LDL and LPa. [Results] The level of ET of Hyperthyroidism group is higher than subclinical hyperthyroidism group and the control group. The level of ET of subclinical Hyperthyroidism group is higher than the control group(P<0.05). The level of Hcy of Hyperthyroidism group and subclinical Hyperthyroidism group was lower than the control group(P<0.05). The level of TG, TC, LDL, LPa of subclinical Hyperthyroidism group are lower than the control group(P<0.05). The level of TG, TC, HDL, LDL, LPa of Hyperthyroidism group are lower than the control group and subclinical hyperthyroidism group (P<0.05). [Conclusions] All of ET, Hcy and lipids participate in the occurrence and development process of hyperthyroidism and subclinical hyperthyroidism. Monitoring the change of related indexes is helpful to predict the transformation of subclinical hyperthyroidism to hyperthyroidism and the occurrence of cardiovascular disease.
    VL  - 7
    IS  - 1
    ER  - 

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Author Information
  • Department of Medical Technology of Cangzhou Medical College, Cangzhou, China; Cangzhou Thyroid Disease Engineering Research Center, Cangzhou, China

  • Laboratory Department of Cangzhou Hospital Integrated of Chinese and Western Medicine, Cangzhou, China

  • Department of Medical Technology of Cangzhou Medical College, Cangzhou, China; Cangzhou Thyroid Disease Engineering Research Center, Cangzhou, China

  • Cangzhou People's Hospital, Cangzhou, China

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