The Association of Meat Consumption and Breast Cancer Risk: A Case Control Study in a Population of Iranian Women
American Journal of Life Sciences
Volume 3, Issue 2-1, March 2015, Pages: 6-11
Received: Nov. 12, 2014; Accepted: Nov. 14, 2014; Published: Nov. 22, 2014
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Authors
Zeinab Karimi, Faculty of Nutrition Sciences and Food Technology, National Nutrition and Food Technology Research Institute, Shahid Beheshti University of Medical Sciences, Tehran, Iran
Zahra Bahadoran, Nutrition and Endocrine Research Center, and Obesity Research Center, Research Institute for Endocrine Sciences, Shahid Beheshti University of Medical Sciences, Tehran, Iran
Anahita Houshiar-rad, National Nutrition and Food Technology Research Institute, Shahid Beheshti University of Medical Sciences, Tehran, Iran
Hamid-Reza Mirzayi, Department of Radiation Oncology, Faculty of Medicine, Shahid Beheshti University of Medical Sciences, Tehran, Iran
Bahram Rashidkhani, Department of Community Nutrition, National Nutrition and Food Technology Research Institute, Faculty of Nutrition Sciences and Food Technology, Shahid Beheshti University of Medical Sciences, Tehran, Iran
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Abstract
Objective: Epidemiologic data do not provide consistent evidence for an association between consumption of meat and breast cancer risk. We conducted a hospital-based case-control study during April and July 2010 among Iranian women to investigate associations between dietary meat intake, its types and breast cancer risk. Methods: One-hundred consecutively recruited cases with newly diagnosed breast cancer were frequency matched to 175 controls by age. Dietary intake was assessed by using a validated semi-quantitative food frequency questionnaire. Odds ratios and 95% confidence interval were obtained by using multiple logistic regression models adjusted for various potentially confounding variables. Results: The mean age of participant was 46.2±8.9 and 45.9±9.4 y in cases and controls, respectively. After adjustment of potential confounders, no association was found between total meat intake and the odds of breast cancer, but the risk of breast cancer in the forth quartile of red meat intake, compared with first quartile, significantly increased (OR=2.43, 95% CI=1.11-5.32). Consumption of poultry > 212 g/week significantly decreased the risk of breast cancer. Higher intake of fish meat decreased the odds of breast cancer (P for trend<0.05), whereas higher intake of processed meat was accompanied with increased the risk of breast cancer (P for trend<0.05). Conclusion: We found a positive association between dietary intake of red meat and processed meat products with the odds of breast cancer, as well as protective effects of fish and poultry intake with breast cancer.
Keywords
Breast Cancer, Meat, Red Meat, Poultry, Fish, Processed Meat
To cite this article
Zeinab Karimi, Zahra Bahadoran, Anahita Houshiar-rad, Hamid-Reza Mirzayi, Bahram Rashidkhani, The Association of Meat Consumption and Breast Cancer Risk: A Case Control Study in a Population of Iranian Women, American Journal of Life Sciences. Special Issue:Nutrition and Cancer. Vol. 3, No. 2-1, 2015, pp. 6-11. doi: 10.11648/j.ajls.s.2015030201.12
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