American Journal of Life Sciences

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Sensitivity Factors and Human Pathology Related to Infections of Producing Escherichia Coli of Shiga-Toxin

Received: 28 November 2016    Accepted: 11 January 2017    Published: 15 April 2017
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Abstract

Escherichia coli O157: H7 is the main serotype E. coli responsible for disease in humans. STEC strains (Shiga-toxin-producing E. coli) are all strains with genes encoding Stx toxin cytotoxic for Vero cell cultures (kidney cell of African green monkey), hence the name "verotoxin"also called"Shiga toxin"because of its great similarity to a toxin produced by Shigella dysenteriae. Infections caused by EHEC (Enterohemorrhagic E. coli) are a major problem due to the extreme severity of the clinical manifestations they can generate. These translate into a banal or bloody diarrhea may develop in 5-8% of cases, mainly in young children, to a serious complication hemolytic uremic syndrome (HUS) or thrombotic thrombocytopenic purpura (TTP) in adults. The identification of susceptibility factors of clinical interest because it may allow early specific treatment of patients at risk of complications.

DOI 10.11648/j.ajls.s.2017050301.19
Published in American Journal of Life Sciences (Volume 5, Issue 3-1, May 2017)

This article belongs to the Special Issue Environmental Toxicology

Page(s) 60-66
Creative Commons

This is an Open Access article, distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution and reproduction in any medium or format, provided the original work is properly cited.

Copyright

Copyright © The Author(s), 2024. Published by Science Publishing Group

Keywords

Enterohemorrhagic E. coli, Factors of Susceptibility, Hemolytic Uremic Syndrome, Shiga-toxin-Producing E. coli, Shigatoxin

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Author Information
  • Laboratory of Applied Microbiology Department of Biology, Faculty of Sciences, Ibn Tofail University, Kenitra, Morocco

  • Laboratory of Medical Analysis, Hospital Hassan II, Agadir, Morocco

  • High Institute of Nursing Professions and Health Techniques, ISPITS, Agadir, Morocco

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  • APA Style

    Saїd Oulkheir, Khadija Ounine, Mohamed Aghrouch, Smail Chadli. (2017). Sensitivity Factors and Human Pathology Related to Infections of Producing Escherichia Coli of Shiga-Toxin. American Journal of Life Sciences, 5(3-1), 60-66. https://doi.org/10.11648/j.ajls.s.2017050301.19

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    ACS Style

    Saїd Oulkheir; Khadija Ounine; Mohamed Aghrouch; Smail Chadli. Sensitivity Factors and Human Pathology Related to Infections of Producing Escherichia Coli of Shiga-Toxin. Am. J. Life Sci. 2017, 5(3-1), 60-66. doi: 10.11648/j.ajls.s.2017050301.19

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    AMA Style

    Saїd Oulkheir, Khadija Ounine, Mohamed Aghrouch, Smail Chadli. Sensitivity Factors and Human Pathology Related to Infections of Producing Escherichia Coli of Shiga-Toxin. Am J Life Sci. 2017;5(3-1):60-66. doi: 10.11648/j.ajls.s.2017050301.19

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  • @article{10.11648/j.ajls.s.2017050301.19,
      author = {Saїd Oulkheir and Khadija Ounine and Mohamed Aghrouch and Smail Chadli},
      title = {Sensitivity Factors and Human Pathology Related to Infections of Producing Escherichia Coli of Shiga-Toxin},
      journal = {American Journal of Life Sciences},
      volume = {5},
      number = {3-1},
      pages = {60-66},
      doi = {10.11648/j.ajls.s.2017050301.19},
      url = {https://doi.org/10.11648/j.ajls.s.2017050301.19},
      eprint = {https://download.sciencepg.com/pdf/10.11648.j.ajls.s.2017050301.19},
      abstract = {Escherichia coli O157: H7 is the main serotype E. coli responsible for disease in humans. STEC strains (Shiga-toxin-producing E. coli) are all strains with genes encoding Stx toxin cytotoxic for Vero cell cultures (kidney cell of African green monkey), hence the name "verotoxin"also called"Shiga toxin"because of its great similarity to a toxin produced by Shigella dysenteriae. Infections caused by EHEC (Enterohemorrhagic E. coli) are a major problem due to the extreme severity of the clinical manifestations they can generate. These translate into a banal or bloody diarrhea may develop in 5-8% of cases, mainly in young children, to a serious complication hemolytic uremic syndrome (HUS) or thrombotic thrombocytopenic purpura (TTP) in adults. The identification of susceptibility factors of clinical interest because it may allow early specific treatment of patients at risk of complications.},
     year = {2017}
    }
    

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    T1  - Sensitivity Factors and Human Pathology Related to Infections of Producing Escherichia Coli of Shiga-Toxin
    AU  - Saїd Oulkheir
    AU  - Khadija Ounine
    AU  - Mohamed Aghrouch
    AU  - Smail Chadli
    Y1  - 2017/04/15
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    N1  - https://doi.org/10.11648/j.ajls.s.2017050301.19
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    JF  - American Journal of Life Sciences
    JO  - American Journal of Life Sciences
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    AB  - Escherichia coli O157: H7 is the main serotype E. coli responsible for disease in humans. STEC strains (Shiga-toxin-producing E. coli) are all strains with genes encoding Stx toxin cytotoxic for Vero cell cultures (kidney cell of African green monkey), hence the name "verotoxin"also called"Shiga toxin"because of its great similarity to a toxin produced by Shigella dysenteriae. Infections caused by EHEC (Enterohemorrhagic E. coli) are a major problem due to the extreme severity of the clinical manifestations they can generate. These translate into a banal or bloody diarrhea may develop in 5-8% of cases, mainly in young children, to a serious complication hemolytic uremic syndrome (HUS) or thrombotic thrombocytopenic purpura (TTP) in adults. The identification of susceptibility factors of clinical interest because it may allow early specific treatment of patients at risk of complications.
    VL  - 5
    IS  - 3-1
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