Exploring the Nigerian Medicinal Plants with Anticancer Activities: A Pharmacological Review
Volume 6, Issue 2, June 2018, Pages: 35-38
Received: Jun. 8, 2018;
Accepted: Aug. 13, 2018;
Published: Sep. 28, 2018
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Abdullahi Danbaba Abdullahi, Department of Chemistry, School of Science Education, Sa’adatu Rimi College of Education, Kumbotso, Nigeria
Rabiatu Kabir Mustapha, Department of Chemistry, Faculty of Science, Yusuf Maitama Sule University, Kofar Nasarawa, Nigeria
Sani Yau, Child Development Centre, Sa’adatu Rimi College of Education, Kumbotso, Nigeria; Consultancy Unit, Sa’adatu Rimi College of Education, Kumbotso, Nigeria
Mustapha Sani Adam, Department of Chemistry, School of Science Education, Sa’adatu Rimi College of Education, Kumbotso, Nigeria
Cancer has become one of the most dangerous diseases and is the leading cause of death in economically developed countries and the second leading cause of death in developing countries. Many indigenous plants are used in herbal medicine to cure various diseases and heal injuries. The use of medicinal plants has become essential due to the presence of several bioactive substances and their availability. Most chemotherapeutic drugs for cancer treatment are molecules identified and isolated from plants or their synthetic derivatives. Anticancer agents from plants currently in clinical use are categorized into four main classes of compounds including; epipodophylltoxins, taxanes camptothecins, and vinca alkaloids. This paper discussed the factors responsible for, different forms of cancer, as well as organs or parts it affect. The paper also explored some Nigerian medicinal plants with anticancer agents. Seventeen medicinal plants were mentioned and confirmed to possess bioactive constituents responsible for cancer therapy.
Abdullahi Danbaba Abdullahi,
Rabiatu Kabir Mustapha,
Mustapha Sani Adam,
Exploring the Nigerian Medicinal Plants with Anticancer Activities: A Pharmacological Review, Modern Chemistry.
Vol. 6, No. 2,
2018, pp. 35-38.
Chavan S. S. et al., (2013). Traditional medicinal plants for anticancer activity. International Journal of Current Pharmaceutical Research, 5(4): 50-54.
Madhuri S. and Pandey G. (2009). Ethnomedicinal plants for prevention and treatment of tumours. International Journal of Green Pharmacy, 3(1):2-5.
Prakash O. M. et al., (2013). Anticancer potential of plants and natural products: A review. American Journal of Pharmacological Sciences, 1(6): 104-115.
Kainsa S. et al., (2012). Medicinal plants of Asian origin having anticancer potential: short review. Asian Journal of Biomedical and Pharmaceutical Sciences, 2(10): 1-7.
Umadevi M. et al., (2013). Traditionally used anticancer herbs in India. Journal of Medicinal Plants Studies, 1(3): 56-
Joshi R. A. (2017). Antrodia camphorata with potential anti-cancerous activities: A review. Journal of Medicinal Plants Studies, 5(1): 284-291.
Amri E. (2014). The role of selected plants families with dietary Ethnomedicinal species used as anticancer. Journal of Medicinal Plants Studies, 2(1): 28-39.
Sultana S. et al., (2014). Medicinal plants combating against cancer- a green anticancer approach. Asian Pacific Journal of Cancer Prevention, 15: 4385-4394.
Hussein A. et al., (2014). Antioxidant and cytotoxic activities of Gmelina arborea ROXB. leaves. British Journal of Pharmaceutical Research, 4(1):125-144.
Ibikunle G. F. et al., (2017). Cytotoxic agents from Nigerian plants: A case study of Spondias mombin Linn (Anacardiaceae) leaves. FUW Trends in Science and Technology Journal, 2(1b): 510-513.
Solowey E. et al., (2014). Evaluating medicinal plants for anticancer activity. The Scientific World Journal, 1-13.
Priya L. M. et al., (2015). Herbal and medicinal plants molecules towards treatment of cancer: A mini review. American Journal of Ethnomedicine, 2(2): 136-142.
Verma S. (2017). Phytochemical and pharmacological study on Argemone mexicana Linn (Papaveraceae). International Journal of Pharmacy, 7(1): 90-93.
Omale J. and Okafor P. N. (2009). Cytotoxicity and antioxidant screening of some selected Nigerian medicinal plants. Asian Journal of Pharmaceutical and Clinical Research, 2(4): 48-53.
Sakarkar D. M. and Deshmukh V. N. (2011). Ethnopharmacological review of traditional medicinal plants for anticancer activity. International Journal of PharmTech Research, 3(1):
Merina N. et al., (2012). Medicinal plants with potential anticancer activities: A review. International Research Journal of Pharmacy, 3(6): 26-30.
Mbhele N. et al., (2015). In vitro studies on the antimicrobial, antioxidant, and antidiabetic potential of Cephalaria gigantea. Bangladdesh Journal of Pharmacol, 10: 214-221.
Ahmad H. A. (2017). A Phyto pharmacological review on a medicinal plants: Holarrhena floribunda. Journal of Medicinal Plants Studies, 5(6): 26-29.
Gulzar H. et al., (2015). Phytochemical screening, antimicrobial and anticancerous activities of two plants extract. Journal of Medicinal Plants Studies, 3(6): 76-81.
Okorondu S. I. et al., (2015). Review on medicinal plants. Nigerian Journal of Microbiology, 29: 3167-3183.
Mushtaq S. (2017). Evaluation of anticancer and antimicrobial activities of selected medicinal plants of Kashmir Himalayas, India. Indian Journal of Traditional Knowledge, 16(1): 141-145.
Rumana A. et al., (2015). Evaluation of In-vitro anticancer activity of stem of Tinospora cordifolia against human breast cancer and vero cell lines. Journal of Medicinal Plants Studies, 3(4): 33-37.
Tiwary B. K. et al., (2015). The in vitro cytotoxic activity of ethnopharmacological important plants of Darjeeling district of west Bengal against different human cancer cell lines. BMC Complementary and Alternative Medicine, 15(22): 1-10.
Nwankwo J. O. (2017). Anticancer potentials of phytochemicals from some indigenous food and medicinal plants of west Africa. Advances in Cancer Prevention, 2(3): 1-7.
Mohanraj R. and Subha S. (2015). Production of 4-ipomeanol, an anticancer agent from the root tuber and rhizogenic callus of Ipomoea batatas Lam: A comparative study. Indian Journal of Experimental Biology, 53: 297-304.
Mohanraj R. and Subha S. (2014). Sweet potato (Ipomoea batatas [L.] Lam) - A valuable Medicinal food: A Review. Journal of Medicinal Food, 17(7): 733-741
Kaushik P. et al., (2014). A comprehensive review on medicinal plants with anticancer activity. Global Journal of Pharmaceutical Education and Research, 3(1-2): 1-13.
Singh D. K. and Luqman S. (2014). Lawsonia inermis (L.): A perspective on anticancer potential of Mehndi/Henna. Biomedical Research and Therapy, 1(4): 112-120.
Hayashi K. et al., (2004). Evaluation of Scopadulciol-Related Molecules for their stimulatory effect on the cytotoxicity of acyclovir and gancyclovir against herpes simplex virus type I Thimidine kinase gene Transfected HeLa cells. Chem. Pharm. Bull. 58(2):1015-1017.
Liu J. (2005). Oleanolic acid and Ursolic acid: Research perspectives. Journal of Ethnopharmacology, 100(1-2): 92-94.
Akram M. et al., (2010). Curcuma longa and Curcumin: A review article. Romanian Journal of Biology and Plant Biology, 5(2):65-70.
Polu P. et al., (2015). Herbal medicinal plants as an anticancer agent. Annals of Phytomedicine, 4(1): 37-45.
Reddy C. M. B. and Reddy G. V. S. (2012). Validated method for vinblastine by spectromphotometry in bulk drug and pharmaceutical formulations. Journal of Chemical and Pharmaceutical Research, 4(7): 3703-707.
Umashanker M. and Shruti S. (2011). Traditional indian herbal medicine used as antipyretic, antiulcer, antidiabetic and anticancer: A review. International Journal of Research in Pharmacy and Chemistry, 1(4): 1152-1159.