Pb(II) Complexes of Schiff Bases Derived from Benzoylhydrazine as the Antibacterial Agents
Volume 3, Issue 1-1, January 2015, Pages: 7-14
Received: Dec. 20, 2014;
Accepted: Dec. 23, 2014;
Published: Jan. 27, 2015
Views 3226 Downloads 326
Mohammad Nasir Uddin, Department of Chemistry, University of Chittagong, Chittagong-4331, Bangladesh
Md. Abdus Salam, Department of Chemistry, University of Chittagong, Chittagong-4331, Bangladesh
Jannat Sultana, Department of Chemistry, University of Chittagong, Chittagong-4331, Bangladesh
Some Pb(II) complexes of dibasic tridentate Schiff base ligands derived from aldehydes/ketones and benzoylhydrazine have been synthesized and characterized by some physico-chemical studies; elemental, spectral (IR, UV, NMR, Mass), magnetic, and conductance analyses. The CHN elemental analysis data showed the formation of 1:1 [M:L] complexes. The obtained molar conductance values revealed non-electrolytic nature. The results of magnetic moment measurements supported diamagnetic phenomenon for the complexes. The infrared spectral data displayed the main coordination sites of ligands towards Pb2+ ions. The electronic spectral results of the complexes showed π→π* (phenyl ring), n→π* (HC=N), CT transition. Based on analytical data trigonal pyramidal geometry for the prepared complexes has been proposed. The antibacterial activity of the prepared complexes was also studied against some gram positive and gram negative bacteria. It is found that some of the complexes are quite effective against tested bacteria.
Mohammad Nasir Uddin,
Md. Abdus Salam,
Pb(II) Complexes of Schiff Bases Derived from Benzoylhydrazine as the Antibacterial Agents, Modern Chemistry. Special Issue: Synthesis and Microbial Screening of Coordination and Organic Compounds.
Vol. 3, No. 1-1,
2015, pp. 7-14.
Syamal, A. & Maurya, M. R. (1986). Synthesis and characterisation of nickel(II), cobalt(II), manganese(II), copper(II), zinc(II), dioxouranium(VI) and dioxomolybdenum(VI) complexes of tridentate dibasic ONO donor Schiff bases derived from 2-benzothiazolecarbohydrazide and salicylaldehyde/2-hydroxy-1-naphthaldehyde. Transition Metal Chem., 11(6), 201-205.
Syamal, A., & Maurya, M. R. (1986). Dioxomolybdenum(VI) complexes with tridentate dibasic Schiff bases derived from various hydrazides. Transition Metal Chem., 11(6), 235-238.
Syamal, A. & Maurya, M. R. (1986). Synthesis and characterization of new dioxomolybdenum(VI) complexes of ONS donor Schiff bases derived from thiosemicarbazide, S-methyldithiocarbazate, S-benzyldithiocarbazate and o-hydroxy-aromatic aldehydes/ketones. Transition Metal Chem, 11(7), 255-258.
Aliyu, H. N. & Ado, I. (2010) Studies of Mn(II), and Ni(II) complexes with Schiff base derived form 2 amino benzoic acid and salicylaldehyde. Bayero J. Pure Appl. Sci., 3(1), 245 – 249.
Johari, R., Kumar, G., Kumar, D. & Singh, S. (2009). Synthesis and antibacterial activity of M (II) Schiff base complex. J. Ind. Council Chem., 26(1), 23-27.
Mounika, K., Anupama, B., Pragathi, J. & Gyanakumari, C. (2010). Synthesis¸ characterization and biological activity of a Schiff base derived from 3-ethoxy salicylaldehyde and 2-amino benzoic acid and its transition metal complexes. J. Sci. Res. 2(3), 513-524.
Samanta, B., Chakraborty, J., Dey, D. K., Gramlich, V. & Mitra, S. (2007). Synthesis, characterization and structural aspects of a new diorganotin(IV) complex with N-(5-bromo-2-hydroxybenzylidene) benzoylhydrazone ligand. Struct Chem., 18, 287–293.
Lalia-Kantouri, M., Tzavellas, L. & Paschalidis, D. (2008). Novel lanthanide complexes with di-2-pyridyl ketone-p-chloro-benzoylhydrazone, Thermal investigation by simultaneous TG/DTG-DTA and IR spectroscopy. J. Thermal Anal. Calori., 91(3), 937–942.
Jang, Y. J., Lee, U. K. & Koo, B. K. (2005). Synthesis and crystal structures of Mn(II), Co(II), Ni(II), Cu(II), and Zn(II) metal complexes with NNO functionalized ligands. Bull. Korean Chem. Soc., 26(6), 925-929.
Ghosh, T., Bandyopadhyay, C., Bhattacharya, S. & Mukherjee, G. (2004). Synthesis, spectral and electrochemical studies of mixed-ligand oxovanadium(IV) and oxovanadium(V) complexes incorporating the tridentate ONO donor schiff base derived from acetylacetone and benzoylhydrazine. Transition metal chem., 29(4), 444-450.
Chowdhury, D. A., Uddin, M. N. & Sarker, M. A. H. (2008). Synthesis and characterization of dioxo-uranium(VI) complexes of some aroylhydrazines and their Schiff bases with acetone. Chiang Mai J. Sci. 35(3), 483-494.
El-Ajaily, M. M., Abdlseed, F. A. & Gweirif, B. (2007). Preparation, characterization and antibacterial activity of some metal ion complexes. E-Journal of Chem., 4, 461-466.
Abdlseed, F. A. & El-ajaily, M. M. (2009). Preparation and spectroscopic investigation of a Schiff base metal complexes. Inter. J. Pharm Tech Res., 1(4), 1097-1103.
McGaryey, B. R., Ozarowski, A., Tian, Z. & Tuck, D. G. (1995). Tin and lead derivatives of a Schiff Base-bis(orthoquinone) ligand. Can. J. Chem. 73, 1213-1222.
Liu, J., Zhang, B., Bowan, W. U., Zhang, K. & Shenli, H. U. (2007). The direct electrochemical synthesis of Ti(II), Fe(II), Cd(II), Sn(II), and Pb(II) complexes with N, N-bis(Salicylidene)-o-phenylenediamine. Turk J Chem, 31, 623-629.
Shaker, S. A. (2010). Preparation and study of some Mn(II), Co(II), Ni(II), Cu(II), Cd(II) and Pb(II) complexes containing heterocyclic nitrogen donor ligands. E-Journal of Chem., 7(4), 1598-1604.
Subudhi, B. B., Panda, P. K. & Sahoo, S. (2007). Synthesis and Evaluation of Antimicrobial Activity of Metal Complexes of 4-(2'-Hydroxy Phenyl Imino)Phenyl Sulphonamide. Iranian J. Pharm. Sci., 3(4), 245.
Malik, S., Kumari, M., Chauhan, S. & Sharma, D. K. (2010). Sulfur-containing Schiff base complexes of iron(III) and lead(II): Synthesis, characterization, antimicrobial activity, and their electrochemical behaviors. Phosphorus, Sulfur, and Silicon and Related Elements, 185(8), 1759 – 1771.
Bhattacharyya, P., Parr, J., Ross, A.T. & Slawin, A. M. Z. (1998). First synthesis of a unique dilead Schiff base complex. J. Chem. Soc., Dalton Trans., 19, 3149-3150.
Zhao, P. S., Li, R. Q., Song, J. & Guo, M. P. (2008) Quantum chemical studies on nicotinato lead(II) complex [Pb(II)(C5H4NCOO)2], Bull. Korean Chem. Soc., 29(3), 546-550.
Gaydos, J. M. & Harrington, B. J. (1982). Agar disk diffusion for the quality control testing of Autobac elution disks. Antimicrob Agents Chemother. 21(3), 516–518.
Chowdhury, D. A., Uddin, M. N. & Lucky, N. (2003). Antimicrobial activities of some dithiocarbamates and their Titanium(IV) complexes. Bull. Pure Appl. Sci., 22C(1), 39-45.
Chowdhury, D. A., Uddin, M. N., Islam, M. T., & Haque, F. (2012). Evaluation of biological activity of dioxouranium complexes of some Schiff base and dithiocarbamate ligands. Orbital-The electronic J. Chem., 4(4), 273-287.