Evaluation of TSH, T4 and T3 in Human Serum: Standardization on Normal Individuals
American Journal of Modern Physics
Volume 2, Issue 4, July 2013, Pages: 202-207
Received: May 28, 2013; Published: Jun. 20, 2013
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Authors
M. A. Samad, Department of Physics, Faculty of Science, University of Rajshahi, Rajshahi-6205, Bangladesh
M. M. Haque, Department of Physics, Faculty of Science, University of Rajshahi, Rajshahi-6205, Bangladesh
M. K. Shah, Center for Nuclear Medicine & Ultrasound, Rajshahi Medical College Hospital, Rajshahi, Bangladesh
M. R. Islam, Center for Nuclear Medicine & Ultrasound, Rajshahi Medical College Hospital, Rajshahi, Bangladesh
M. C. Mia, Department of Physics, Faculty of Science, University of Rajshahi, Rajshahi-6205, Bangladesh
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Abstract
A cross-sectional study of thyrotropin (TSH), thyroxine (T4) and triiodothyronine (T3) in human serum was performed aiming to define their normal values. In total, 201 assays were performed on 70 normal individuals, 26 men and 44 women, with ages ranging from 2 to 84 years. Serum TSH was measured with a highly sensitive immunoradiometric assay (IRMA) kit and T4 & T3 were determined with commercially available radioimmunoassay (RIA) kits. The normal values of TSH, T4 and T3 observed in the present study were 0.5 - 5.0 mIU/L, 55 - 169 nmol/L and 1.2 - 3.4 nmol/L, respectively, and their means (±SD) were 2.06±1.08 mIU/L, 113.21±27.62 nmol/L and 1.96±0.54 nmol/L, respectively. The results obtained were found to be in excellent agreement with the previously reported series. It is, therefore, expected that the present study will contribute some useful data in literature to set up normal values of serum TSH, T4 and T3.
Keywords
Thyroid Functions, Thyrotropin, Thyroxine, Triiodothyronine, Standardization
To cite this article
M. A. Samad, M. M. Haque, M. K. Shah, M. R. Islam, M. C. Mia, Evaluation of TSH, T4 and T3 in Human Serum: Standardization on Normal Individuals, American Journal of Modern Physics. Vol. 2, No. 4, 2013, pp. 202-207. doi: 10.11648/j.ajmp.20130204.14
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