Preparation, Physical Characterization and Antibacterial Activity of Ni (II), Cu (II), Co (II), Cd (II), Zn (II) and Cr (III) Schiff Base Complex Compounds
Science Journal of Chemistry
Volume 6, Issue 2, April 2018, Pages: 17-23
Received: Jun. 13, 2018;
Accepted: Jun. 27, 2018;
Published: Jul. 23, 2018
Views 1108 Downloads 228
Md. Motahar Hossain, Department of Chemistry, University of Rajshahi, Rajshahi, Bangladesh
Md. Abul Bashar, Department of Textile Engineering, Khwaja Yunus Ali University, Sirajganj, Bangladesh
Md. Nuruzzaman Khan, Department of Chemistry, Begum Rokeya University, Rangpur, Rangpur, Bangladesh
Pijush Kanti Roy, Department of Chemistry, Mawlana Bhashani Science and Technology University, Santosh, Tangail, Bangladesh
Md. Siddik Ali, Department of Chemistry, University of Rajshahi, Rajshahi, Bangladesh
Md. Akhter Farooque, Department of Chemistry, University of Rajshahi, Rajshahi, Bangladesh
A Schiff base (SB) derived from p-hydroxy benzaldehyde and 4-aminobenzoic acid. The transition metal complexes of Ni (II), Cu (II), Co (II), Cd (II), Zn (II) and Cr (III) were prepared separately with the Schiff base (SB), which were used as ligand. Several physical tools, in particular; elemental analysis, molar conductivity, magnetic susceptibility, infrared spectroscopy (IR), electronic absorption spectroscopy (ESR) to investigate the chemical structure of the prepared transition metal complexes. The elemental analysis data show the formation of 1:2 [M1:2L] and 1:3 [M2:3L] complexes of the formula of M2+L2 and M3+L3, respectively where M2+ =Ni (II), Cu (II), Co (II), Cd (II), Zn (II) and M3+= Cr (III) and L = Schiff base (SB). The molar conductance (conductivity) measurements were revealed that all the complexes are nonelectrolyte in nature. The infrared (IR) spectral studies indicated the binding sites of the Schiff base ligand with the transition metal ions. The magnetic susceptibility measurements and electronic spectral results supported the predicted coordination geometry of the complexes and magnetic properties (para or dia-magnetic nature) of the complex compounds. The free Schiff base and its complexes have been tested for their antimicrobial activities against several human pathogenic (two gram-positive and two gram-negative) bacteria. The obtained results showed that the complex compounds exhibit moderate to strong antimicrobial activity compared with kanamycin and ampicillin.
Md. Motahar Hossain,
Md. Abul Bashar,
Md. Nuruzzaman Khan,
Pijush Kanti Roy,
Md. Siddik Ali,
Md. Akhter Farooque,
Preparation, Physical Characterization and Antibacterial Activity of Ni (II), Cu (II), Co (II), Cd (II), Zn (II) and Cr (III) Schiff Base Complex Compounds, Science Journal of Chemistry.
Vol. 6, No. 2,
2018, pp. 17-23.
Alim, A., Zahan, M. K. E., Haque, M. M. and Tarafder, M. T. H., Synthesis and Characterization of Some Metal Complexes of Cu (II), Ni (II), Zn (II), Cd (II), Sn (II), Co (II), Sb (III) AND Fe (III) Containing Bidentate Schiff Base of Smdtc, Science Journal of Chemistry, 2015; 3 (3): 35-39.
Banu, L. A., Islam, M. S., Al-Bari, M. A. A. and Zahan, M. K. E., Synthesis and Characterization with Antibacterial, Antifungal, Cytotoxicity Studies on the Co (II), Ni (II) and Cu (II) complexes of Tridentate ONO Coordinating Schiff Bases and Heterocyclic Amines, International Journal of Recent Advances in Multidisciplinary Research, 2015; 02 (01): 145-148.
Shampa, J. A., Islam, M. R., Hossain, M. S., Rahman, G. T., Zakaria, C. M. and Zahan, M. K. E., Physiochemical and Antibacterial Activity Investigation on Noble Schiff Base Cu (II) Complex, American Journal of Heterocyclic Chemistry, 2017; 3 (4): 37-41.
Hossain, M. S., Islam, M. A., Zakaria, C. M., Haque, M. M., Mannan, M. A. and Md. Zahan, M. K. E., Synthesis, Spectral and Thermal Characterization with Antimicrobial Studies on Mn (II), Fe (II), Co (II) and Sn (II) Complexes of Tridentate N, O Coordinating Novel Schiff Base Ligand, J. Chem. Bio. Phy. Sci. Sec. A, 2017; 7 (1): 041-052.
Hossain, M. S., Sarker, S., Shaheed, A. S. M. E., Hossain, M. M., Bari, A. A., Karim, M. R., Zakaria, C. M., and Zahan, M. K. E., Thermal and Spectral Characterization of Cr (III), Co (II) and Cd (II) Metal Complexes Containing Bis Imine Novel Schiff Base Ligand Towards Potential Biological Application, Chemical and Biomolecular Engineering, 2017; 2 (1): 41-50.
Patel, K. M., Patel, K. N., Patel N. H. and Patel M. N., Synthesis, characterization, and antimicrobial activities of some transition metal complexes with a tridentate dibasic Schiff base and bidentate 2, 2’-bipyridylamine. Synth. React. Inorg. Met-Org. Chem., 2001; 239.
Temel H., Cakir Ü., Ugras H. I. and Sekerci M., The Synthesis, Characterization and Conductance Studies of New Co (III), Cu (II), Ni (II) and Zn (II) Complexes with Schiff Base Derived from 1, 2-bis- (o-aminophenoxy) Ethane and Salicylaldehyde. Journal of Coord. Chem., 2003; 56: 943-951.
Liang Y., SU, B., Zhao I. and Sun W., The Synthesis of New Asymmetric Double Schiff Bases Containing a New o‐Amino Benzoic Acid Derivative. Synthesis Communications, 2004; 34: 3235-3242.
Venkataraman, N. S., Kuppuraj, G. and Rajajopal, S., Metal-salen complexes as efficient catalysts for the oxygenation of heteroatom containing organic compounds-synthetic and mechanistic aspects. Coord. Chem. Rev., 2005; 249: 1249-1268.
Mohamed, G. G., Omar, M. M. and Hindy, A. M., Metal complexes of Schiff bases: preparation, characterization and biological activity. J. Turk. Chem., 2006; 30: 361-382.
Diego, M., Veronica, D., Claudia, P., Jean, P. T. and Sandra, S., Synthesis, characterization and antioxidant activity of water soluble Mn (III) complexes of sulphonato-substituted Schiff base ligands. Journal of inorganic Biochemistry, 2010; 104: 496-502.
Khalil, M., Ismail, E., Mohamed, G., Zayed E. and Badr, A., Synthesis and characterization of a novel schiff base metal complexes and their application in determination of iron in different types of natural water. Open J. Inorg. Chem., 2012; 2: 13-21.
Abu-El-Wafa, S. M., El-Wakiel, N. A., Issa R. M., and Mansour, R. A., Formation of novel mono-and multi-nuclear complexes of Mn (II), Co (II) and Cu (II) with bisazo-dianils containing the pyrimidine moiety: Thermal, magnetic and spectral studies. J. Coord. Chem., 2005; 58: 683-694.
Etaiw S. H., Abd El-Aziz D. M., Abd El-Zaher E. H. and Ali E. A., Synthesis, spectral, antimicrobial and antitumor assessment of Schiff base derived from 2-aminobenzothiazole and its transition metal complexes, Spectrochim. Acta A., 2011; 79: 1331–1337.
Ueda J. I., Takai N. and Shiazue Y., Reactive Oxygen Species Generated from the Reaction of Copper (II) Complexes with Biological Reductants Cause DNA Strand Scission. Arch. Biochem. Biophys., 1998; 357: 231-239.
Radhakrishnan P. K., Complexes of lanthanide perchlorates with 4-N- (2′-hydroxy-1′-naphthylidene) aminoantipyrine, Polyhedron. 1986; 5: 995-998.
Maurya R. C., Mishra D. D., Pandey M., Shukla P. and Rathour R., Synthesis and spectral studies of octacoordinated dioxouranium (VI) complexes with some Schiff bases derived from 4-Acetyl-2, 3-Dimethyl-l- (4-Methylphenyl)-3-Pyrazoline-5-One and aromatic amines. Synth. React. Inorg. Met. Org. Chem., 1993; 23: 161-174.
Kudrat-E- Z. M., Islam, M. S. and Bashar M. A., Synthesis, Characterization and antimicrobial activity of Some Metal Complexes of Mn (II), Fe (III) Co (II), Ni (II), Cu (II) and Sb (III) Containing Bidentate Schiff base of SMDTC. Russian Journal of general chemistry, 2015; 85 (3): 667-672.
Geary, W. J., The use of conductivity measurements in organic solvents for the characterization of coordination compounds, Coord. Chem. Rev., 1971; 7: 81-122.
Shamsuddin, A. A. K., Benui:, K. Dey., Zainul, S. A., and datta:, M., J. Bang. Chem. Soc., 1999; 12 (1): 25.
Md. Saddam Hossain, C. M. Zakaria, M. M. Haque, and Md. Kudrat-E- Zahan, (2016) Spectral and Thermal Characterization with Antimicrobial Activity on Cr (III) and Sn (II) Complexes containing N, O Donor Novel Schiff Base Ligand. International Journal of Chemical Studie, 2016; 4 (6): 08-11.
Hutchinson, B., Takemoto J. and Nakamoto, K., Metal isotope effect on metal-ligand vibration. II. Tris complexes of 2, 2/-bipyridine and 1, 10-phenanthroline, J. Am. Chem. Soc., 1970, 92: 3335.
Saito, Y., Takemoto, J., Hutchinson B. and Nakamoto, K., Infrared studies of coordination compounds containing low-oxidation state metals. I. Tris (2,-2/-bipyridine) and tris (1, 10-phenanthroline) complexes, Inorg. Chem., 1972, 11: 2003.
Nakamoto, K., Infrared spectra of inorganic and coordination compounds. John Wiley and Sons. New York, 1963, 112: 227.
Lever, A. B. P., Inorganic Electronic Spectroscopy, 2nd Edn. Elsevier (1984).
Md. Saddam Hossain, Shudeepta Sarker, A. S. M. Elias Shaheed, Md. Mamun Hossain, Abdul Alim-Al-Bari, Md. Rabiul Karim, C. M. Zakaria, Md. Kudrat-E-Zahan. (2017) Thermal and Spectral Characterization of Cr (III), Co (II) and Cd (II) Metal Complexes Containing Bis-Imine Novel Schiff Base Ligand Towards Potential Biological Application. Chemical and Biomolecular Engineering., 2017, 2 (1): 41-50.
El-ajaily, M. M., Maihub, A. A., Hudere S. S. & Ben Saber S. M. (2006). Nickel II Chelate of Schiff base derived from 4-dimethyl-amino-benzaaldehyde with Systeine. Asian Journal of Chemistry Society, 2006; 18 (4): 2427- 2430.
F. M. Morad, F. M., M. M. EL. ajaily, M. M. EL. and Gweirif, S. B., Preparation, Physical Characterization and Antibacterial Activity of Ni (II) Schiff Base Complex, Journal of Science and Its Applications, 2007; 1 (1): 72-78.