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A Novel Biosensor for Determination of Glucose Based on MWCNTs/ZrO2-Pt Nanocomposite

Received: 12 March 2017    Accepted: 8 April 2017    Published: 20 September 2017
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Abstract

Multiwalled carbon nanotubes/ZrO2-Pt(MWCNTs/ZrO2-Pt) composite was synthesized by a chemical route. The structure and composition of the MWCNTs/ZrO2-Pt composite were confirmed by means of transmission electron microscopy, and Raman spectroscopy. Due to the good electrochemical activity property of MWCNTs/ZrO2-Pt composite, a glucose biosensor was constructed by absorbing glucose oxidase (GOD) on the hybrid material. A direct electron transfer process is observed at the MWCNTs/ZrO2-Pt/GOD-modified glassy carbon electrode. The glucose biosensor has a linear range from 4.0 to 24.0 mM, which is suitable for glucose determination by real samples. It should be worthwhile noting that, from 4.0 to 12.0mM, the cathodic peak currents of the biosensor decrease linearly with increasing the glucose concentrations in human blood. Meanwhile, the resulting biosensor can also prevent the effects of interfering species. Moreover, the biosensor exhibits satisfying reproducibility, good operational stability and storage stability. Therefore, the MWCNTs/ZrO2-Pt /GOD biocomposite could be promisingly applied to determine blood sugar concentration in the practical clinical analysis.

Published in Advances in Materials (Volume 6, Issue 5)
DOI 10.11648/j.am.20170605.13
Page(s) 66-72
Creative Commons

This is an Open Access article, distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution and reproduction in any medium or format, provided the original work is properly cited.

Copyright

Copyright © The Author(s), 2024. Published by Science Publishing Group

Keywords

Multiwalled Carbon Nanotubes, Electrochemical Biosensors, Platinum Nanoparticles

References
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Cite This Article
  • APA Style

    Mohamed Abdelfattah Ibrahim, Meshari A. Al-Sharif, Ali A. Keshk. (2017). A Novel Biosensor for Determination of Glucose Based on MWCNTs/ZrO2-Pt Nanocomposite. Advances in Materials, 6(5), 66-72. https://doi.org/10.11648/j.am.20170605.13

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    ACS Style

    Mohamed Abdelfattah Ibrahim; Meshari A. Al-Sharif; Ali A. Keshk. A Novel Biosensor for Determination of Glucose Based on MWCNTs/ZrO2-Pt Nanocomposite. Adv. Mater. 2017, 6(5), 66-72. doi: 10.11648/j.am.20170605.13

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    AMA Style

    Mohamed Abdelfattah Ibrahim, Meshari A. Al-Sharif, Ali A. Keshk. A Novel Biosensor for Determination of Glucose Based on MWCNTs/ZrO2-Pt Nanocomposite. Adv Mater. 2017;6(5):66-72. doi: 10.11648/j.am.20170605.13

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  • @article{10.11648/j.am.20170605.13,
      author = {Mohamed Abdelfattah Ibrahim and Meshari A. Al-Sharif and Ali A. Keshk},
      title = {A Novel Biosensor for Determination of Glucose Based on MWCNTs/ZrO2-Pt Nanocomposite},
      journal = {Advances in Materials},
      volume = {6},
      number = {5},
      pages = {66-72},
      doi = {10.11648/j.am.20170605.13},
      url = {https://doi.org/10.11648/j.am.20170605.13},
      eprint = {https://article.sciencepublishinggroup.com/pdf/10.11648.j.am.20170605.13},
      abstract = {Multiwalled carbon nanotubes/ZrO2-Pt(MWCNTs/ZrO2-Pt) composite was synthesized by a chemical route. The structure and composition of the MWCNTs/ZrO2-Pt composite were confirmed by means of transmission electron microscopy, and Raman spectroscopy. Due to the good electrochemical activity property of MWCNTs/ZrO2-Pt composite, a glucose biosensor was constructed by absorbing glucose oxidase (GOD) on the hybrid material. A direct electron transfer process is observed at the MWCNTs/ZrO2-Pt/GOD-modified glassy carbon electrode. The glucose biosensor has a linear range from 4.0 to 24.0 mM, which is suitable for glucose determination by real samples. It should be worthwhile noting that, from 4.0 to 12.0mM, the cathodic peak currents of the biosensor decrease linearly with increasing the glucose concentrations in human blood. Meanwhile, the resulting biosensor can also prevent the effects of interfering species. Moreover, the biosensor exhibits satisfying reproducibility, good operational stability and storage stability. Therefore, the MWCNTs/ZrO2-Pt /GOD biocomposite could be promisingly applied to determine blood sugar concentration in the practical clinical analysis.},
     year = {2017}
    }
    

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  • TY  - JOUR
    T1  - A Novel Biosensor for Determination of Glucose Based on MWCNTs/ZrO2-Pt Nanocomposite
    AU  - Mohamed Abdelfattah Ibrahim
    AU  - Meshari A. Al-Sharif
    AU  - Ali A. Keshk
    Y1  - 2017/09/20
    PY  - 2017
    N1  - https://doi.org/10.11648/j.am.20170605.13
    DO  - 10.11648/j.am.20170605.13
    T2  - Advances in Materials
    JF  - Advances in Materials
    JO  - Advances in Materials
    SP  - 66
    EP  - 72
    PB  - Science Publishing Group
    SN  - 2327-252X
    UR  - https://doi.org/10.11648/j.am.20170605.13
    AB  - Multiwalled carbon nanotubes/ZrO2-Pt(MWCNTs/ZrO2-Pt) composite was synthesized by a chemical route. The structure and composition of the MWCNTs/ZrO2-Pt composite were confirmed by means of transmission electron microscopy, and Raman spectroscopy. Due to the good electrochemical activity property of MWCNTs/ZrO2-Pt composite, a glucose biosensor was constructed by absorbing glucose oxidase (GOD) on the hybrid material. A direct electron transfer process is observed at the MWCNTs/ZrO2-Pt/GOD-modified glassy carbon electrode. The glucose biosensor has a linear range from 4.0 to 24.0 mM, which is suitable for glucose determination by real samples. It should be worthwhile noting that, from 4.0 to 12.0mM, the cathodic peak currents of the biosensor decrease linearly with increasing the glucose concentrations in human blood. Meanwhile, the resulting biosensor can also prevent the effects of interfering species. Moreover, the biosensor exhibits satisfying reproducibility, good operational stability and storage stability. Therefore, the MWCNTs/ZrO2-Pt /GOD biocomposite could be promisingly applied to determine blood sugar concentration in the practical clinical analysis.
    VL  - 6
    IS  - 5
    ER  - 

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Author Information
  • Department of Chemistry, Faculty of Science, University of Tabuk, Tabuk, Saudi Arabia; Department of Chemistry, Faculty of Science, El-Arish University, El-Arish, North Sinai, Egypt

  • Department of Chemistry, Faculty of Science, University of Tabuk, Tabuk, Saudi Arabia

  • Department of Chemistry, Faculty of Science, University of Tabuk, Tabuk, Saudi Arabia

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