International Journal of Sensors and Sensor Networks
Volume 7, Issue 1, March 2019, Pages: 1-8
Received: Jul. 1, 2019;
Accepted: Jul. 25, 2019;
Published: Aug. 10, 2019
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Joshua Robert Harvey, Department of Biomedical Engineering, Worcester Polytechnic Institute, Worcester, USA
Yitzhak Mendelson, Department of Biomedical Engineering, Worcester Polytechnic Institute, Worcester, USA
The costs of pressure injury treatments continue to rise with a steadily aging population and consistent pressure injury incidence rates. Evidence suggests that the bioimpedance of living tissues changes in response to continuous pressure loading and may be useful as an indicator for the onset of pressure injuries. Therefore, the development of a low-cost, accurate, and portable sensor capable of measuring the bioimpedance of human skin has practical significance in the development of pressure injury prevention devices. This paper reports the design and characterization of a system for measuring skin impedance based on the AD5933 impedance analyzer. The sensor was tested for accuracy via measurements of a simplified electrical equivalent skin model. Long duration measurement stability was assessed over 24 hours and skin measurement repeatability was performed on the volar forearm. The power consumption was measured both during idle and when transmitting data for each major component. The sensor demonstrated accuracies similar to those reported for other AFE’s used in conjunction with the AD5933. Additionally, the sensor shows good stability over long measurement durations as well as good repeatability when measuring the skin bioimpedance on the volar forearm. Power consumption was as expected and future suggestions for lowering the overall circuit power consumption and size are presented.
Joshua Robert Harvey,
A Portable Sensor for Skin Bioimpedance Measurements, International Journal of Sensors and Sensor Networks.
Vol. 7, No. 1,
2019, pp. 1-8.
Van Gilder, C., et al., Results of the 2008-2009 International Pressure Ulcer Prevalence Survey and a 3-year, acute care, unit-specific analysis. Ostomy Wound Manage, 2009. 55(11): p. 39-45.
Brem, H., et al., High cost of stage IV pressure ulcers. Am J Surg, 2010. 200(4): p. 473-7.
Nakagami, G., et al., Predicting delayed pressure ulcer healing using thermography: a prospective cohort study. J Wound Care, 2010. 19(11): p. 465-6, 468, 470 passim.
Aoi, N., et al., Ultrasound assessment of deep tissue injury in pressure ulcers: possible prediction of pressure ulcer progression. Plast Reconstr Surg, 2009. 124(2): p. 540-50.
Baumgarten, M., et al., Validity of pressure ulcer diagnosis using digital photography. Wound Repair Regen, 2009. 17(2): p. 287-90.
Bates-Jensen, B. M., et al., Subepidermal moisture predicts erythema and stage 1 pressure ulcers in nursing home residents: a pilot study. J Am Geriatr Soc, 2007. 55(8): p. 1199-205.
Bates-Jensen, B. M., H. E. McCreath, and V. Pongquan, Subepidermal moisture is associated with early pressure ulcer damage in nursing home residents with dark skin tones: pilot findings. J Wound Ostomy Continence Nurs, 2009. 36(3): p. 277-84.
Swisher, S. L., et al., Impedance sensing device enables early detection of pressure ulcers in vivo. Nat Commun, 2015. 6: p. 6575.
Ching, C. T., et al., Tissue electrical properties monitoring for the prevention of pressure sore. Prosthet Orthot Int, 2011. 35(4): p. 386-94.
Noveletto F., B.-F. P., Dutra D., Analog Front-End for the Integrated Circuit AD5933 Used in Electrical Bioimpedance Measurements, in Latin American Conference on Bioimpedance IFMBE Proceedings. 2016, Springer: Singapore.
Aroom, K. R., et al., Bioimpedance analysis: a guide to simple design and implementation. J Surg Res, 2009. 153(1): p. 23-30.
Bouchaala, D., et al., A high accuracy voltage controlled current source for handheld bioimpedance measurement. 2013. 1-4.
Harder, R., et al., Smart Multi-Frequency Bioelectrical Impedance Spectrometer for BIA and BIVA Applications. IEEE Trans Biomed Circuits Syst, 2016. 10(4): p. 912-9.
Margo, C., et al., A four-electrode low frequency impedance spectroscopy measurement system using the AD5933 measurement chip. Physiol Meas, 2013. 34(4): p. 391-405.
Seoane, F., et al., Simple voltage-controlled current source for wideband electrical bioimpedance spectroscopy: Circuit dependences and limitations. Vol. 22. 2011. 115801.
Armstrong, L. E., et al., Bioimpedance spectroscopy technique: intra-, extracellular, and total body water. Med Sci Sports Exerc, 1997. 29(12): p. 1657-63.
Nescolarde, L., et al., Localized bioimpedance to assess muscle injury. Physiol Meas, 2013. 34(2): p. 237-45.
Khalil, S. F., M. S. Mohktar, and F. Ibrahim, The theory and fundamentals of bioimpedance analysis in clinical status monitoring and diagnosis of diseases. Sensors (Basel), 2014. 14(6): p. 10895-928.
Kyle, U. G., et al., Bioelectrical impedance analysis--part I: review of principles and methods. Clin Nutr, 2004. 23(5): p. 1226-43.
Wagner, D. R., et al., Bioelectrical impedance as a discriminator of pressure ulcer risk. Adv Wound Care, 1996. 9(2): p. 30-7.
Lukaski, H. C. and M. Moore, Bioelectrical impedance assessment of wound healing. J Diabetes Sci Technol, 2012. 6(1): p. 209-12.
Chang, Z. Y., G. M. Pop, and G. M. Meijer, A comparison of two- and four-electrode techniques to characterize blood impedance for the frequency range of 100 Hz to 100 MHz. IEEE Trans Biomed Eng, 2008. 55(3): p. 1247-9.
Schwan, H. P., Electrode polarization impedance and measurements in biological materials. Ann N Y Acad Sci, 1968. 148(1): p. 191-209.
Rosell, J., et al., Skin impedance from 1 Hz to 1 MHz. IEEE Trans Biomed Eng, 1988. 35(8): p. 649-51.
Kim, Y. and H. W. Woo, A prototype system and reconstruction algorithms for electrical impedance technique in medical body imaging. Clin Phys Physiol Meas, 1987. 8 Suppl A: p. 63-70.
Analog Devices. 1 MSPS, 12-Bit Impedance Converter, Network Analyzer. AD5933 datasheet 2017 May 1, 2019]; Available from: https://www.analog.com/media/en/technical-documentation/data-sheets/AD5933.pdf.
Cole, K. S. and R. H. Cole, Dispersion and Absorption in Dielectrics I. Alternating Current Characteristics. The Journal of Chemical Physics, 1941. 9(4): p. 341-351.
Geddes, L. A. and M. E. Valentinuzzi, Temporal changes in electrode impedance while recording the electrocardiogram with "dry" electrodes. Ann Biomed Eng, 1973. 1(3): p. 356-67.
Higashino, T., et al., Combination of thermographic and ultrasonographic assessments for early detection of deep tissue injury. Int Wound J, 2014. 11(5): p. 509-16.
Brienza, D. M., et al., The relationship between pressure ulcer incidence and buttock-seat cushion interface pressure in at-risk elderly wheelchair users. Arch Phys Med Rehabil, 2001. 82(4): p. 529-33.