Doppler Ultrasound Assessment in Women with Threatened Abortion
Clinical Medicine Research
Volume 2, Issue 3, May 2013, Pages: 24-28
Received: Apr. 10, 2013; Published: May 2, 2013
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Gustavo Romero-Gutiérrez, Dept. Obstetrics and Gynecology. UMAE. Hospital de Gineco-Pediatría Nº 48, IMSS, León, Guanajuato. México
Antonio Abraham Huebe-Martínez, Dept. Radiology. Hospital of Family Medicine N° 51, IMSS, León, Guanajuato, México
Immer Amaral-Navarro, Dept. Obstetrics and Gynecology. UMAE. Hospital de Gineco-Pediatría Nº 48, IMSS, León, Guanajuato. México
Armando Saúl Ruiz-Treviño, Dept. Obstetrics and Gynecology. UMAE. Hospital de Gineco-Pediatría Nº 48, IMSS, León, Guanajuato. México
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Objective: To determine which variables obtained by Doppler ultrasound are associated with the outcome of patients with threatened abortion. Study design: We carried out a cross-sectional study. The patient population included patients with pregnancy less than 20 weeks, who were hospitalized with the diagnosis of threatened abortion. Results: We followed the outcome of 223 patients and found 32 patients (14.3%) who aborted and 191 patients (85.7%) who did not abort. The fetal heart rate for the group who aborted was significantly lower than the group who did not abort (143 ± 2.9 vs. 154 ± 3.6 beats per minute, respectively), p = 0.002; the resistance index of uterine artery was higher (0.79 ± 0.07 vs. 0.76 ± 0.09, respectively), p = 0.018; and the resistance index of trophoblastic flow was higher (0.55 ± 0.04 vs. 0.50 ± 0.06, respectively), p = 0.041. The resistance index of umbilical artery and corpus luteum were not statistically different. Conclusion: Alterations of fetal heart rate, resistance index of uterine artery and trophoblastic flow are associated with adverse outcome in women with threatened abortion.
Doppler Ultrasound, Threatened Abortion, Resistance Index, Uterine Artery, Trophoblastic Flow
To cite this article
Gustavo Romero-Gutiérrez, Antonio Abraham Huebe-Martínez, Immer Amaral-Navarro, Armando Saúl Ruiz-Treviño, Doppler Ultrasound Assessment in Women with Threatened Abortion, Clinical Medicine Research. Vol. 2, No. 3, 2013, pp. 24-28. doi: 10.11648/j.cmr.20130203.11
Sotiriadis A, Papatheodorou S, Makrydimas G. Threatened miscarriage: evaluation and management. BMJ 2004; 329:152-155.
Bae S, Karnitis J. Triple ultrasound markers including fetal cardiac activity are related to miscarriage risk. Fertil Steril 2011; 96:1145-1148.
Papaioannou GI, Syngelaki A, Maiz N, Ross JA, Nicolaides KH. Ultrasonographic prediction of early miscarriage. Hum Reprod 2011; 26:1685-1692.
Benson CB, Doubilet PM. Slow embryonic heart rate in early first trimester: indicator of poor pregnancy outcome. Radiology 1994; 192:343-344.
Kurjak A, Crvenkovic G, Salihagic A, Zalud I, Miljan M. The assessment of normal early pregnancy by transvaginal color Doppler ultrasonography. J Clin Ultrasound 1993; 21:3-8.
Jaffe R, Dorgan A, Abramowicz JS. Color Doppler imaging of the uteroplacental circulation in the first trimester: value in predicting pregnancy failure or complication. ARJ Am J Roentgenol 1995; 164:1255-1258.
Alcázar JL, Laparte C, López-Garcia G. Corpus luteum blood flow in abnormal early pregnancy. J Ultrasound Med 1996; 15:645-649.
El-mashad AI, Mohamed MA, Farag MA, Ahmad MK, Ismail Y. Role of uterine artery Doppler velocimetry indices and plasma adrenomedullin level in women with unexplained recurrent pregnancy loss. J Obstet Gynaecol Res 2011; 37:51-57.
Pellizzari P, Pozzan C, Marchiori S, Zen T, Gangemi M. Assessment of uterine artery blood flow in normal first-trimester pregnancies and in those complicated by uterine bleeding. Ultrasound Obstet Gynecol 2002; 19:366-370.
Goslin RG, King DH. Ultrasound angiology. In: Marcus AW, Adamson L. Editors. Arteries and veins. Edimburg: Chur-chill-Livingstone, 1975: 61-98.
Leible S, Cumsille F, Walton R, Muñoz H, Jankelevich J, Sepulveda W. Discordant uterine artery velocity waveforms as a predictor of subsequent miscarriage in early viable pregnancies. Am J Obstet Gynecol 1998; 179:1587-1593.
Salim A, Zalud I, Farmakides G, Shulman H, Kurjak A, Latin V. Corpus luteum blood flow in normal and abnormal early pregnancy: evaluation with transvaginal color and pulsed Doppler sonography. J Ultrasound Med 1994; 13:971-975.
Arduini D, Rizzo G. Umbilical artery velocity waveforms in early pregnancy: A transvaginal color Doppler study. J Clin Ultrasound 1991; 19:335-339.
Alcázar JL. Intraobserver variability of pulsatility index measurements in three fetal vessels in the first trimester. J Clin Ultrasound 1997; 25:366-371.
Hamela-Olkowska A, Wiech K, Jalinik K, Zarviewski D, Kornatowski L, Dangel J. Evaluation of the embryonic and foetal heart rate at 6(+0) to 11(+6) weeks of gestation. Ginekol Pol 2009; 80:188-192.
Cooley SM, Donnelly JC, Walsh T, MacMahon C, Gillan J, Geary MP. The impact of umbilical and uterine artery Doppler indices on antenatal course, labor and delivery in a low risk primigravid population. J Perinat Med 2011; 39:143-149.
Iacovella C, Franchi M, Egbor M, Bhide A, Thilaganathan B. Relationship of first-trimester uterine artery Doppler to late stillbirth. Prenat Diagn 2012; 17:1-5.
Alcázar JL, Ruiz-Pérez ML. Uteroplacental circulation in patients with first-trimester threatened abortion. Fertil Steril 2000; 73:130-5.
Jauniaux E, Johns J, Burton GJ. The role of ultrasound imaging in diagnosing and investigating early pregnancy failure. Ultrasound Obstet Gynecol 2005; 25:613-624.
Yazawa H, Soeda S, Hiraiwa T, Takaiwa M, Hasegawa-Endo S, Kojima M, Fujimori K. Prospective evaluation of the incidence of uterine vascular malformations developing after abortion or delivery. J Minim Invasive Gynecol 2013. pii: S1553-4650(12)01381-7. doi: 10.1016/j.jmig.2012.12.008. [Epub ahead of print].
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