Neo-Revascularization as the Potential Treatment for Patient Suffering from Pulmonary Arterial Hypertension (Myth or Reality)
Clinical Medicine Research
Volume 2, Issue 3, May 2013, Pages: 32-36
Received: Apr. 28, 2013; Published: May 30, 2013
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Authors
Aris Lacis, Clinic of Pediatric Cardiology and Cardiac Surgery, University Children Hospital, Riga, Latvia
Inguna Lubaua, Riga Stradins University, Riga, Latvia
Valts Ozolins, Clinic of Pediatric Cardiology and Cardiac Surgery, University Children Hospital, Riga, Latvia
Eriks Jekabsons, Pauls Stradins Clinical University Hospital, Riga, Latvia
Andis Lacis, Riga Stradins University, Riga, Latvia
Mara Ratniece, Pauls Stradins Clinical University Hospital, Riga, Latvia
Andrejs Erglis, Latvian Institute of Cardiology, Riga, Latvia
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Abstract
Pulmonary arterial hypertension (APAH, IPAH) is a devastating, progressive disease with increasingly debilitating symptoms [1,2].Intrapulmonary delivery of autologous stem cells could be beneficial for pathogenetic treatment for patients with severe pulmonary arterial hypertension.Two patients with severe pulmonary artery hypertension received intrapulmonary autologous mesenchymal (mononuclear) stem cell transplantation and stem cell transplantation in pulmonary arteries. Patients were examined by scintigraphy of lungs during the periods 12, 14 and 27 months after stem cell transplantation. We find out that perfusion in all lung segments were improved after 14 and 27 months.
Keywords
Stem Cell Transplantation, Intrapulmonary Delivery, Pulmonary Artery Hypertension, Pulmonary Vascular Resistance
To cite this article
Aris Lacis, Inguna Lubaua, Valts Ozolins, Eriks Jekabsons, Andis Lacis, Mara Ratniece, Andrejs Erglis, Neo-Revascularization as the Potential Treatment for Patient Suffering from Pulmonary Arterial Hypertension (Myth or Reality), Clinical Medicine Research. Vol. 2, No. 3, 2013, pp. 32-36. doi: 10.11648/j.cmr.20130203.13
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