Atrial Septal Aneurysm Is Always Linked To Right-Left Shunt and Cardio embolic Risk
Clinical Medicine Research
Volume 2, Issue 4, July 2013, Pages: 48-52
Received: May 13, 2013; Published: Jun. 20, 2013
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Authors
Sarah Mangiafico, Dept, Cardio-Thoraco-Vascular, AOU Policlinic University of Catania, Catania, Italy
Ines Paola Monte, Dept, Cardio-Thoraco-Vascular, AOU Policlinic University of Catania, Catania, Italy
Vincenzo Lavanco, Dept, Cardio-Thoraco-Vascular, AOU Policlinic University of Catania, Catania, Italy
Lucio Raffaello Tropea, Dept, Cardio-Thoraco-Vascular, AOU Policlinic University of Catania, Catania, Italy
Antonio Andrea Arcidiacono, Dept, Cardio-Thoraco-Vascular, AOU Policlinic University of Catania, Catania, Italy
Maria Concetta di Pasqua, Dept, Cardio-Thoraco-Vascular, AOU Policlinic University of Catania, Catania, Italy
Letizia Santonoceto, Dept, Cardio-Thoraco-Vascular, AOU Policlinic University of Catania, Catania, Italy
Giovanni Millan, Dept, Cardio-Thoraco-Vascular, AOU Policlinic University of Catania, Catania, Italy
Corrado Tamburino, Dept, Cardio-Thoraco-Vascular, AOU Policlinic University of Catania, Catania, Italy; Excellence through Newest Advances (ETNA)
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Abstract
Atrial septal aneurysm when associated to other cardiac abnormalities, such as patent foramen ovale, Chiari network or Eustachian Membrane, is a well-known recognised risk factor for cerebral embolism. Aim of study is to assess if isolated atrial septal aneurysm could be considered statistically related to cryptogenic stroke, considering the strong clinical impact that this association could have on these patients outcome. 579 patients were investigated for a suspected patent foramen ovale using transthoracic echocardiography, in order to evaluate the presence of atrial septal aneurysm and to identify other potential cardiac embolic sources. The patients with atrial septal aneurysm underwent transcranic echodoppler and transoesophageal echocardiography examination with contrast solution during Valsalva manoeuvre.209/579 (36%) patients where we made diagnosis of atrial septal aneurysm. In this cohort of patients transcranic echodoppler showed a patent foramen ovale in 114/209 (54%), whereas transoesophageal echocardiography in 111/209 (53%); 6/114 (5%) pa-tients with a positive transcranic echodoppler had a normal transoesophageal echocardiography examination and 3/95 (3%) with normal transcranic echodoppler had a positive transoesophageal echocardiography. Transcranic echodoppler vs. transoesophageal echocardiography sensibility was 97% and specificity 94%. Only 13/98 (13%) of patients with isolated atrial septal aneurysm and 23/111 (26%) with patent foramen ovale had history of cryptogenic stroke. According to our data, isolated atrial septal aneurysm could not be considered an independent risk factor for cryptogenic stroke.
Keywords
Atrial Septum Aneurysm, Stroke, Echocardiography
To cite this article
Sarah Mangiafico, Ines Paola Monte, Vincenzo Lavanco, Lucio Raffaello Tropea, Antonio Andrea Arcidiacono, Maria Concetta di Pasqua, Letizia Santonoceto, Giovanni Millan, Corrado Tamburino, Atrial Septal Aneurysm Is Always Linked To Right-Left Shunt and Cardio embolic Risk, Clinical Medicine Research. Vol. 2, No. 4, 2013, pp. 48-52. doi: 10.11648/j.cmr.20130204.12
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