Cervical Lymphadenopathy with Special Reference to Fine Needle Aspiration Cytology Corroborated with Histological Examination: A Cross Sectional Study

Sukdeb Biswas; Kaushik Ghosh; Sisir Chakraborty; Rajdip Hazra; Rabindra Nath Biswas; Susmita Ghosh; Kaushik Das; Niladri Sarkar

doi:doi:10.11648/j.cmr.20140302.12

Cervical Lymphadenopathy with Special Reference to Fine Needle Aspiration Cytology Corroborated with Histological Examination: A Cross Sectional Study

Sukdeb Biswas, Kaushik Ghosh, Sisir Chakraborty, Rajdip Hazra, Rabindra Nath Biswas, Susmita Ghosh, Kaushik Das, Niladri Sarkar

Published in Clinical Medicine Research (Volume 3, Issue 2)

Received: 6 January 2014 Accepted: Published: 20 February 2014

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Abstract

Introduction: Cervical lymphadenoparthy is a common presentation of many diseases, though it is mostly tubercular in origin in developing countries. This cross sectional study was done to corroborate fine needle aspiration cytology (FNAC) findings with histopathological examinations (HPE) in cervical lymphadenopathy. Materials and methods: 120 patients of both sexes attending the FNAC unit of Nilratan Sircar Medical College and Hospital, Kolkata were enrolled in this study. They were evaluated by thorough clinical examination followed by routine investigations, FNAC and histopathological examination (HPE). Results: There was maximum corroboration of FNAC and HPE reports in tubercular lymphadenitis (76 v/s 76) and Hodgkin’s disease (2 v/s 2) followed by metastatic carcinoma (20 v/s 16) and non specific lymphadenitis (14 v/s 5) respectively. Overall correlation was 88.4% (excluding 8 cases where FNAC results were inconclusive due to unsatisfactory smear). The sensitivity, specificity, positive predictive value and negative predictive value of FNAC to diagnose tubercular lymphadenopathies were 86.36%. 100.0%, 100.0% and 72.73% respectively. In case of metastatic CA, these were 100.0%, 96.15%, 80.0% and 100.0% respectively. Conclusion: FNAC is simple, safe, quick, cheap, acceptable yet accurate method of establishing the etiology in cases of cervical lymphadenopathy.

Published in	Clinical Medicine Research (Volume 3, Issue 2)
DOI	10.11648/j.cmr.20140302.12
Page(s)	17-20
Creative Commons	This is an Open Access article, distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution and reproduction in any medium or format, provided the original work is properly cited.
Copyright	Copyright © The Author(s), 2024. Published by Science Publishing Group

Keywords

Cervical Lymphadenopathy, Fine Needle Aspiration Cytology, Histopathology

References

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[2]	Young JE, Archibald SD, Shier KJ. Needle aspiration cytologic biopsy in head and neck masses. Am J Surg. 1981;142(4):484-9.
[3]	Mahbod G, Koasri F, Tafreshi MA. Fine needle aspiration cytology in diagnosis of nonthyroidal neck masses. Acta Medica Iranica. 2002;40(1):49-51.
[4]	Pandit AA, Candes FB, Khubchandhani SR. Fine needle aspiration cytology of lymph nodes. J Postgrad Med. 1987;33(3):134-6.
[5]	Carroll CM, Nazeer U, Timon CI. The accuracy of fine -needle aspiration biopsy in the diagnosis of head and neck masses. Ir J Med sci. 1998;167(3):149-51.
[6]	Bardales RH, Baker SJ, Mukunyadzi P. Fine- needle aspiration cytology findings in 214 cases of nonparotid lesion of the head. Diagn cytopathol. 2000;22(4):211-7.
[7]	Khiery J, Ahmed ME. Cervical lymphadenopathy in Khartoum. JTrop Med Hyg. I992;95(6):416-9.
[8]	AL-Khafaji BM, NestokBR, Katz RL. Fine needle aspiration of 154 parotid masses with histologic correlation: Ten -year experience at the university of Texas M.D.Anderson cancer center. Cancer. 1998;84(3):153-9.
[9]	Djupesland P, Sauer T, Ferng A. Puncture cytology in tumours of the head and neck region. Tidsskr Nor Laegeforen. 1993;113(16):1985-7.
[10]	Patt BS, Schaefer SD, Vuitch F. Role of fine-needle aspiration in the evaluation of neck masses. Med Clin North Am. 1993;77(3):611-23
[11]	McGuirt WF, McCabe BF. Significance of node biopsy before definitive treatment of cervical metastatic carcinoma. Laryngoscope. 1978;88(4):594-7.

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Sukdeb Biswas, Kaushik Ghosh, Sisir Chakraborty, Rajdip Hazra, Rabindra Nath Biswas, et al. (2014). Cervical Lymphadenopathy with Special Reference to Fine Needle Aspiration Cytology Corroborated with Histological Examination: A Cross Sectional Study. Clinical Medicine Research, 3(2), 17-20. https://doi.org/10.11648/j.cmr.20140302.12

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ACS Style

Sukdeb Biswas; Kaushik Ghosh; Sisir Chakraborty; Rajdip Hazra; Rabindra Nath Biswas, et al. Cervical Lymphadenopathy with Special Reference to Fine Needle Aspiration Cytology Corroborated with Histological Examination: A Cross Sectional Study. Clin. Med. Res. 2014, 3(2), 17-20. doi: 10.11648/j.cmr.20140302.12

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AMA Style

Sukdeb Biswas, Kaushik Ghosh, Sisir Chakraborty, Rajdip Hazra, Rabindra Nath Biswas, et al. Cervical Lymphadenopathy with Special Reference to Fine Needle Aspiration Cytology Corroborated with Histological Examination: A Cross Sectional Study. Clin Med Res. 2014;3(2):17-20. doi: 10.11648/j.cmr.20140302.12

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@article{10.11648/j.cmr.20140302.12,
  author = {Sukdeb Biswas and Kaushik Ghosh and Sisir Chakraborty and Rajdip Hazra and Rabindra Nath Biswas and Susmita Ghosh and Kaushik Das and Niladri Sarkar},
  title = {Cervical Lymphadenopathy with Special Reference to Fine Needle Aspiration Cytology Corroborated with Histological Examination: A Cross Sectional Study},
  journal = {Clinical Medicine Research},
  volume = {3},
  number = {2},
  pages = {17-20},
  doi = {10.11648/j.cmr.20140302.12},
  url = {https://doi.org/10.11648/j.cmr.20140302.12},
  eprint = {https://article.sciencepublishinggroup.com/pdf/10.11648.j.cmr.20140302.12},
  abstract = {Introduction: Cervical lymphadenoparthy is a common presentation of many diseases, though it is mostly tubercular in origin in developing countries. This cross sectional study was done to corroborate fine needle aspiration cytology (FNAC) findings with histopathological examinations (HPE) in cervical lymphadenopathy. Materials and methods: 120 patients of both sexes attending the FNAC unit of Nilratan Sircar Medical College and Hospital, Kolkata were enrolled in this study. They were evaluated by thorough clinical examination followed by routine investigations, FNAC and histopathological examination (HPE). Results: There was maximum corroboration of FNAC and HPE reports in tubercular lymphadenitis (76 v/s 76) and Hodgkin’s disease (2 v/s 2) followed by metastatic carcinoma (20 v/s 16) and non specific lymphadenitis (14 v/s 5) respectively. Overall correlation was 88.4% (excluding 8 cases where FNAC results were inconclusive due to unsatisfactory smear). The sensitivity, specificity, positive predictive value and negative predictive value of FNAC to diagnose tubercular lymphadenopathies were 86.36%. 100.0%, 100.0% and 72.73% respectively. In case of metastatic CA, these were 100.0%, 96.15%, 80.0% and 100.0% respectively. Conclusion: FNAC is simple, safe, quick, cheap, acceptable yet accurate method of establishing the etiology in cases of cervical lymphadenopathy.},
 year = {2014}
}

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TY  - JOUR
T1  - Cervical Lymphadenopathy with Special Reference to Fine Needle Aspiration Cytology Corroborated with Histological Examination: A Cross Sectional Study
AU  - Sukdeb Biswas
AU  - Kaushik Ghosh
AU  - Sisir Chakraborty
AU  - Rajdip Hazra
AU  - Rabindra Nath Biswas
AU  - Susmita Ghosh
AU  - Kaushik Das
AU  - Niladri Sarkar
Y1  - 2014/02/20
PY  - 2014
N1  - https://doi.org/10.11648/j.cmr.20140302.12
DO  - 10.11648/j.cmr.20140302.12
T2  - Clinical Medicine Research
JF  - Clinical Medicine Research
JO  - Clinical Medicine Research
SP  - 17
EP  - 20
PB  - Science Publishing Group
SN  - 2326-9057
UR  - https://doi.org/10.11648/j.cmr.20140302.12
AB  - Introduction: Cervical lymphadenoparthy is a common presentation of many diseases, though it is mostly tubercular in origin in developing countries. This cross sectional study was done to corroborate fine needle aspiration cytology (FNAC) findings with histopathological examinations (HPE) in cervical lymphadenopathy. Materials and methods: 120 patients of both sexes attending the FNAC unit of Nilratan Sircar Medical College and Hospital, Kolkata were enrolled in this study. They were evaluated by thorough clinical examination followed by routine investigations, FNAC and histopathological examination (HPE). Results: There was maximum corroboration of FNAC and HPE reports in tubercular lymphadenitis (76 v/s 76) and Hodgkin’s disease (2 v/s 2) followed by metastatic carcinoma (20 v/s 16) and non specific lymphadenitis (14 v/s 5) respectively. Overall correlation was 88.4% (excluding 8 cases where FNAC results were inconclusive due to unsatisfactory smear). The sensitivity, specificity, positive predictive value and negative predictive value of FNAC to diagnose tubercular lymphadenopathies were 86.36%. 100.0%, 100.0% and 72.73% respectively. In case of metastatic CA, these were 100.0%, 96.15%, 80.0% and 100.0% respectively. Conclusion: FNAC is simple, safe, quick, cheap, acceptable yet accurate method of establishing the etiology in cases of cervical lymphadenopathy.
VL  - 3
IS  - 2
ER  -

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Author Information

Sukdeb Biswas

Department of Pathology, Nilratan Sircar Medical College and Hospital, Kolkata, India
Kaushik Ghosh

Department of Medicine, Malda Medical College and Hospital, Malda, India
Sisir Chakraborty

Department of Medicine, College of Medicine and Sagore Dutta Hospital, Kolkata, India
Rajdip Hazra

Department of Anesthesiology, Nilratan Sircar Medical College and Hospital, Kolkata, India
Rabindra Nath Biswas

Department of Dermatology, Murshidabad Medical College and Hospital, Berhampore, India
Susmita Ghosh

Department of Anesthesiology, Bangur Institute of Neurosciences, Kolkata, India
Kaushik Das

Department of Medicine, Malda Medical College and Hospital, Malda, India
Niladri Sarkar

Department of Medicine, Burdwan Medical College, Burdwan, India

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APA Style

Sukdeb Biswas, Kaushik Ghosh, Sisir Chakraborty, Rajdip Hazra, Rabindra Nath Biswas, et al. (2014). Cervical Lymphadenopathy with Special Reference to Fine Needle Aspiration Cytology Corroborated with Histological Examination: A Cross Sectional Study. Clinical Medicine Research, 3(2), 17-20. https://doi.org/10.11648/j.cmr.20140302.12

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ACS Style

Sukdeb Biswas; Kaushik Ghosh; Sisir Chakraborty; Rajdip Hazra; Rabindra Nath Biswas, et al. Cervical Lymphadenopathy with Special Reference to Fine Needle Aspiration Cytology Corroborated with Histological Examination: A Cross Sectional Study. Clin. Med. Res. 2014, 3(2), 17-20. doi: 10.11648/j.cmr.20140302.12

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AMA Style

Sukdeb Biswas, Kaushik Ghosh, Sisir Chakraborty, Rajdip Hazra, Rabindra Nath Biswas, et al. Cervical Lymphadenopathy with Special Reference to Fine Needle Aspiration Cytology Corroborated with Histological Examination: A Cross Sectional Study. Clin Med Res. 2014;3(2):17-20. doi: 10.11648/j.cmr.20140302.12

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@article{10.11648/j.cmr.20140302.12,
  author = {Sukdeb Biswas and Kaushik Ghosh and Sisir Chakraborty and Rajdip Hazra and Rabindra Nath Biswas and Susmita Ghosh and Kaushik Das and Niladri Sarkar},
  title = {Cervical Lymphadenopathy with Special Reference to Fine Needle Aspiration Cytology Corroborated with Histological Examination: A Cross Sectional Study},
  journal = {Clinical Medicine Research},
  volume = {3},
  number = {2},
  pages = {17-20},
  doi = {10.11648/j.cmr.20140302.12},
  url = {https://doi.org/10.11648/j.cmr.20140302.12},
  eprint = {https://article.sciencepublishinggroup.com/pdf/10.11648.j.cmr.20140302.12},
  abstract = {Introduction: Cervical lymphadenoparthy is a common presentation of many diseases, though it is mostly tubercular in origin in developing countries. This cross sectional study was done to corroborate fine needle aspiration cytology (FNAC) findings with histopathological examinations (HPE) in cervical lymphadenopathy. Materials and methods: 120 patients of both sexes attending the FNAC unit of Nilratan Sircar Medical College and Hospital, Kolkata were enrolled in this study. They were evaluated by thorough clinical examination followed by routine investigations, FNAC and histopathological examination (HPE). Results: There was maximum corroboration of FNAC and HPE reports in tubercular lymphadenitis (76 v/s 76) and Hodgkin’s disease (2 v/s 2) followed by metastatic carcinoma (20 v/s 16) and non specific lymphadenitis (14 v/s 5) respectively. Overall correlation was 88.4% (excluding 8 cases where FNAC results were inconclusive due to unsatisfactory smear). The sensitivity, specificity, positive predictive value and negative predictive value of FNAC to diagnose tubercular lymphadenopathies were 86.36%. 100.0%, 100.0% and 72.73% respectively. In case of metastatic CA, these were 100.0%, 96.15%, 80.0% and 100.0% respectively. Conclusion: FNAC is simple, safe, quick, cheap, acceptable yet accurate method of establishing the etiology in cases of cervical lymphadenopathy.},
 year = {2014}
}

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TY  - JOUR
T1  - Cervical Lymphadenopathy with Special Reference to Fine Needle Aspiration Cytology Corroborated with Histological Examination: A Cross Sectional Study
AU  - Sukdeb Biswas
AU  - Kaushik Ghosh
AU  - Sisir Chakraborty
AU  - Rajdip Hazra
AU  - Rabindra Nath Biswas
AU  - Susmita Ghosh
AU  - Kaushik Das
AU  - Niladri Sarkar
Y1  - 2014/02/20
PY  - 2014
N1  - https://doi.org/10.11648/j.cmr.20140302.12
DO  - 10.11648/j.cmr.20140302.12
T2  - Clinical Medicine Research
JF  - Clinical Medicine Research
JO  - Clinical Medicine Research
SP  - 17
EP  - 20
PB  - Science Publishing Group
SN  - 2326-9057
UR  - https://doi.org/10.11648/j.cmr.20140302.12
AB  - Introduction: Cervical lymphadenoparthy is a common presentation of many diseases, though it is mostly tubercular in origin in developing countries. This cross sectional study was done to corroborate fine needle aspiration cytology (FNAC) findings with histopathological examinations (HPE) in cervical lymphadenopathy. Materials and methods: 120 patients of both sexes attending the FNAC unit of Nilratan Sircar Medical College and Hospital, Kolkata were enrolled in this study. They were evaluated by thorough clinical examination followed by routine investigations, FNAC and histopathological examination (HPE). Results: There was maximum corroboration of FNAC and HPE reports in tubercular lymphadenitis (76 v/s 76) and Hodgkin’s disease (2 v/s 2) followed by metastatic carcinoma (20 v/s 16) and non specific lymphadenitis (14 v/s 5) respectively. Overall correlation was 88.4% (excluding 8 cases where FNAC results were inconclusive due to unsatisfactory smear). The sensitivity, specificity, positive predictive value and negative predictive value of FNAC to diagnose tubercular lymphadenopathies were 86.36%. 100.0%, 100.0% and 72.73% respectively. In case of metastatic CA, these were 100.0%, 96.15%, 80.0% and 100.0% respectively. Conclusion: FNAC is simple, safe, quick, cheap, acceptable yet accurate method of establishing the etiology in cases of cervical lymphadenopathy.
VL  - 3
IS  - 2
ER  -

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