Hematological Malignancies: Analysis of Myelogram Results over 21 Years in Lome Teaching Hospitals
Clinical Medicine Research
Volume 4, Issue 4, July 2015, Pages: 111-115
Received: May 17, 2015; Accepted: Jun. 7, 2015; Published: Jul. 4, 2015
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Authors
Irenee Messanh Kueviakoe, Faculty of Health Sciences, University of Lome, Lome, Togo; Hematology Laboratory of Campus Teaching Hospital of Lome, Lome, Togo; Hematology Laboratory of Sylvanus Olympio Teaching Hospital of Lome, Lome, Togo
Essohana Padaro, Faculty of Health Sciences, University of Lome, Lome, Togo; Hematology Laboratory of Campus Teaching Hospital of Lome, Lome, Togo
Kossi Agbetiafa, Faculty of Health Sciences, University of Lome, Lome, Togo; Hematology Laboratory of Campus Teaching Hospital of Lome, Lome, Togo
Yao Layibo, Hematology Laboratory of Campus Teaching Hospital of Lome, Lome, Togo
Malewe Kolou, Faculty of Health Sciences, University of Lome, Lome, Togo; Hematology Laboratory of Campus Teaching Hospital of Lome, Lome, Togo
Ahoefa Vovor, Faculty of Health Sciences, University of Lome, Lome, Togo; Hematology Laboratory of Sylvanus Olympio Teaching Hospital of Lome, Lome, Togo
Akuete Yvon Segbena, Faculty of Health Sciences, University of Lome, Lome, Togo; Hematology Laboratory of Campus Teaching Hospital of Lome, Lome, Togo
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Abstract
Objectives: Determine the frequency of malignancies diagnosed in myelogram seen in hematology services of Campus and Sylvanus Olympio Teaching Hospitals in Lome from 1992 to 2013. Study the epidemiology profile of these diseases. Materials and methods: It was an analytical retrospective study of 469 cases of malignancies diagnosed in 1511 myelograms during 21 years in both teaching hospital of Lome. Results: Blood disorders represent 31.70% of the results of myelogram performed during 21 years in the Teaching Hospital of Lome. Each year, there is an average of 22.3 cases diagnosed hematological malignancies. The most hematological malignancies were Kahler's disease (28.57%), chronic myeloid leukemia (24.52%), chronic lymphocytic leukemia (22.17%), acute lymphoblastic leukemia (12.58%) and acute myeloid leukemia (8.10%). Other (4.05%) were represented by the essential hypereosinophilic syndrome (4 cases), hairy cell leukemia (4 cases), Sezary lymphoma (3 cases), essential thrombocythemia (3 cases), Waldenstrom's disease (2 cases), acute myelomonocytic leukemia (1 case), prolymphocytic leukemia (1 case) and plasma cell leukemia (1 case). By gender, the CLL is most predominant in women against CML in men. Hemopathies were observed at all ages of life. Conclusion: Hematological malignancies are diagnosed in the Teaching Hospital of Campus and Sylvanus Olympio in Lome with a high relatively frequency. This prevalence must be higher if all cases of malignancies diagnosed in Togo were recorded in a national cancer register. This study aims to knowledge of epidemiological aspects of hematological malignancies and improve the care of patients with hematological malignancies by the provision of adequate anti-mitotic drugs.
Keywords
Hematological Malignancies, Frequency, Epidemiology, Togo
To cite this article
Irenee Messanh Kueviakoe, Essohana Padaro, Kossi Agbetiafa, Yao Layibo, Malewe Kolou, Ahoefa Vovor, Akuete Yvon Segbena, Hematological Malignancies: Analysis of Myelogram Results over 21 Years in Lome Teaching Hospitals, Clinical Medicine Research. Vol. 4, No. 4, 2015, pp. 111-115. doi: 10.11648/j.cmr.20150404.14
References
[1]
Mahon F-X. Leucémie myéloïde chronique et inhibition de la tyrosine kinase. Rev Med Interne 2001; 22: 894-9
[2]
Bories D. Physiopathologie moléculaire de la leucémie myéloïde chronique. Hématologie 2001;7:6-12.
[3]
Lokrou A, Toutou T, Diallo A, Groga-Bada, Ouedraogo Y, Koutouan A, Tea N, Niamkey E, Soubeyrand J, Beda Y. Leucose et Lymphomes dans un service de Médecine Interne à Abidjan. Med; Afr. Noire, 1988, 35 (4), 305-310.
[4]
Toutou T. Contribution à l’étude du myélome multiple en milieu africain. A propos de 24 cas dont 22 autochtones. Thèse : Méd : Abidjan : 1981 ; 313.
[5]
Segbena A.Y. Contribution à l’étude des hémopathies lymphoïdes malignes chez le Noir Africain. Thèse : Abidjan : 1991, 1261.
[6]
Koffi K.G, Sanogo I, Trazo D, Toure A.H, Tolo A, N'Guessan K, Danho N.C, Kouakou N, Sangare A. Caractéristiques du myélome multiple du noir africain. Expérience de la Côte d'Ivoire, Méd. Afr. Noire, 2000, vol. 47, n° 10 , pp. 430 – 435.
[7]
Marie J.P, Delmer A, Herait P. Hématologie pratique Impact–Internat 1992,139-203
[8]
Atinoto K. Profil clinique, biologique et thérapeutique de la leucémie lymphoïde chronique dans les CHU de Lomé. Mém Ass Med : Lomé 2000 ; pp 25-47.
[9]
Guihot F. Chronic myeloid leukaemia. Textbook of malignant haematology (1999).
[10]
Dokekias E.A, Malanda F. La leucémie myéloïde chronique quel avenir thérapeutique en Afrique noire ? Revue : Tunisie médicale. [Tunis. méd.] , 2003, vol. 81, no 3, pp. 172 – 179
[11]
Zittoun R, Samama M, Marie J.P. Leucémies et états apparentés In : Manuel d’Hématologie Paris : Doin : 1988 ; 397-427.
[12]
Yao T, Tea D.N, Rain J.D. Leucémie lymphoïde chronique en Côte d’Ivoire. Méd. Trop. 51,4, oct.-déc. 1991, 417-420.
[13]
Tea D, Yao T, Rain J D. Aspects particuliers de la leucémie lymphoïde chronique (L.L.C.) en Côte d’Ivoire Rev. Méd. Côte d’Ivoire, 1982, 16, (57), 37-40.
[14]
Carli P M, Milan C, Bordes M, Bonhomme J. Etude de l’incidence de la leucémie lymphoïde chronique dans le département de la Côte d’Or. Nouv. Rev. Fr. hémato, 1986, 28, 23-26.
[15]
Dighiero G, Travade P, Chevret S, Fenaux P, Chastang C, Binet J L. The French Cooperative Group on CLL: B-cell chronic lymphocytic leukaemia. Present status and future direction. Blood 1991; 78: 1901.
[16]
Desablens B. Leucémie lymphoïde chronique. Diagnostic, évolution et pronostic. Rev. Prat. (Paris), 1990, 40, (23), 2195-2198.
[17]
Vernant J.P, Brun B. Leucémies aiguës. In : Hématologie Paris : Flammarion : 1986 ; pp. 471-504.
[18]
Dokekias E.A, Bidzouta-Matingou P, Malanda F, Ntsihou D, Nzingoula S, SANOGO L. Configuration épidémiologique et cytologique des leucémies aiguës au Centre Hospitalier et Universitaire de Brazzaville, Revue : Tunisie médicale. [Tunis. méd.], 2004, vol. 82, no 11, pp. 1019 – 1025.
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