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Effect of Conservative Treatment for Refracture in Cemented Vertebrae After Percutaneous Vertebroplasty: A Long Term Follow-up

Received: 15 March 2016    Accepted: 5 April 2016    Published: 26 April 2016
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Abstract

By a long term follow-up, we evaluated the effects of conservative treatment for refracture of cemented vertebrae after percutaneous vertebroplasty (PVP). 12 patients of 324 patients who underwent PVP from January 2012 to August 2014, with back pain, were confirmed refracture in cemented vertebrae. 7 patients got conservative treatment: the usage of analgesics, osteoporosis medication, brace and physical therapy. Visual analogue seale (VAS) and Oswestry disability index (ODI) were evaluated at 7 days, 1, 3 and 12 months after treatment. Patients were followed up for 21.3 ± 11.2 months. Compared with that before treatment, VAS and ODI scores were significantly decreased after treatment (P < 0.05). VAS and ODI scores were also decreased significantly among 7 days, 1 and 3 months after treatment (P < 0.05). No remarkable difference was found between 3 and 12 month (P > 0.05). Further, there were no complications happened, such as leg phlebothrombosis, decubitus and hypostatic pneumonia. Thus, the results of our conservative treatment were optimal. Accordingly, the ratio of refracture in cemented vertebrae after PVP is low, but it is critical for back pain after PVP which should be pay enough attention for clinicians. Conservative treatment can relieve pain and improve spine function, without obvious complications.

Published in Clinical Medicine Research (Volume 5, Issue 3)
DOI 10.11648/j.cmr.20160503.11
Page(s) 20-23
Creative Commons

This is an Open Access article, distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution and reproduction in any medium or format, provided the original work is properly cited.

Copyright

Copyright © The Author(s), 2024. Published by Science Publishing Group

Keywords

Percutaneous Vertebroplasty, Refracture in Cemented Vertebrae, Conservative Treatment, Long Term Follow-up

References
[1] Wang, D., W. X. Dai, J. Feng, C. Ma, and D. H. Wu, [Efficacy evaluation of percutaneous vertebroplasty via an extra-pedicular approach for osteoporotic compression fracture]. Zhonghua Yi Xue Za Zhi, 2013, 93(11): 845-8.
[2] Tang, H., J. Zhao, and C. Hao, Osteoporotic vertebral compression fractures: surgery versus non-operative management. J Int Med Res, 2011, 39(4): 1438-47.
[3] Huang, H., S. He, W. Fang, H. Zhu, J. Guo, G. Deng, G. Zhu, Y. Qin, and G. Teng, [Percutaneous vertebroplasty for treatment of painful osteoporotic vertebral compression fractures: a retrospective analysis of clinical efficacy]. Zhonghua Yi Xue Za Zhi, 2014, 94(27): 2119-22.
[4] Li, Y. A., C. L. Lin, M. C. Chang, C. L. Liu, T. H. Chen, and S. C. Lai, Subsequent vertebral fracture after vertebroplasty: incidence and analysis of risk factors. Spine (Phila Pa 1976), 2012, 37(3): 179-83.
[5] Blasco, J., A. Martinez-Ferrer, J. Macho, L. San Roman, J. Pomes, J. Carrasco, A. Monegal, N. Guanabens, and P. Peris, Effect of vertebroplasty on pain relief, quality of life, and the incidence of new vertebral fractures: a 12-month randomized follow-up, controlled trial. J Bone Miner Res, 2012, 27(5): 1159-66.
[6] Ahn, Y., J. H. Lee, H. Y. Lee, S. H. Lee, and S. H. Keem, Predictive factors for subsequent vertebral fracture after percutaneous vertebroplasty. J Neurosurg Spine, 2008, 9(2): 129-36.
[7] Heo, D. H., D. K. Chin, Y. S. Yoon, and S. U. Kuh, Recollapse of previous vertebral compression fracture after percutaneous vertebroplasty. Osteoporos Int, 2009, 20(3): 473-80.
[8] He, S. C., G. J. Teng, G. Deng, W. Fang, J. H. Guo, G. Y. Zhu, and G. Z. Li, Repeat vertebroplasty for unrelieved pain at previously treated vertebral levels with osteoporotic vertebral compression fractures. Spine (Phila Pa 1976), 2008, 33(6): 640-7.
[9] Chiu, Y. C., S. C. Yang, H. S. Chen, Y. H. Kao, Y. K. Tu, and K.C. Chung, Clinical evaluation of repeat percutaneous vertebroplasty for symptomatic cemented vertebrae. J Spinal Disord Tech, 2012, 25(8): E245-53.
[10] Guo, J. B., Y. Zhu, B. L. Chen, B. Xie, W. Y. Zhang, Y. J. Yang, Y. S. Yue, and X. Q. Wang, Surgical versus non-surgical treatment for vertebral compression fracture with osteopenia: a systematic review and meta-analysis. PLoS One, 2015, 10(5): e0127145.
[11] Chang, X., Y. F. Lv, B. Chen, H. Y. Li, X. B. Han, K. Yang, W. Zhang, Y. Zhou, and C. Q. Li, Vertebroplasty versus kyphoplasty in osteoporotic vertebral compression fracture: a meta-analysis of prospective comparative studies. Int Orthop, 2015, 39(3): 491-500.
[12] Shengzhong, M., W. Dongjin, W. Shiqing, S. Yang, R. Peng, M. Wanli, and G. Chunzheng, Modification of percutaneous vertebroplasty for painful old osteoporotic vertebral compression fracture in the elderly: preliminary report. Injury, 2012, 43(4): 486-9.
[13] Ma, X. L., D. Xing, J. X. Ma, W. G. Xu, J. Wang, and Y. Chen, Balloon kyphoplasty versus percutaneous vertebroplasty in treating osteoporotic vertebral compression fracture: grading the evidence through a systematic review and meta-analysis. Eur Spine J, 2012, 21(9): 1844-59.
[14] Huang, Z., S. Wan, L. Ning, and S. Han, Is unilateral kyphoplasty as effective and safe as bilateral kyphoplasties for osteoporotic vertebral compression fractures? A meta-analysis. Clin Orthop Relat Res, 2014, 472(9): 2833-42.
[15] Chen, H., P. Tang, Y. Zhao, Y. Gao, and Y. Wang, Unilateral versus bilateral balloon kyphoplasty in the treatment of osteoporotic vertebral compression fractures. Orthopedics, 2014, 37(9): e828-35.
[16] Kearney, P. M., C. Baigent, J. Godwin, H. Halls, J. R. Emberson, and C. Patrono, Do selective cyclo-oxygenase-2 inhibitors and traditional non-steroidal anti-inflammatory drugs increase the risk of atherothrombosis? Meta-analysis of randomised trials. BMJ, 2006, 332(7553): 1302-8.
[17] Browning, R., J. L. Jackson, and P. G. O'Malley, Cyclobenzaprine and back pain: a meta-analysis. Arch Intern Med, 2001, 161(13): 1613-20.
[18] Wong, C. C. and M. J. McGirt, Vertebral compression fractures: a review of current management and multimodal therapy. J Multidiscip Healthc, 2013, 6: 205-14.
[19] Dai, L. Y., L. S. Jiang, and S. D. Jiang, Conservative treatment of thoracolumbar burst fractures: a long-term follow-up results with special reference to the load sharing classification. Spine (Phila Pa 1976), 2008, 33(23): 2536-44.
[20] Gnanenthiran, S. R., S. Adie, and I. A. Harris, Nonoperative versus operative treatment for thoracolumbar burst fractures without neurologic deficit: a meta-analysis. Clin Orthop Relat Res, 2012, 470(2): 567-77.
Cite This Article
  • APA Style

    Jing Wang, Min Chen, Jiang Du. (2016). Effect of Conservative Treatment for Refracture in Cemented Vertebrae After Percutaneous Vertebroplasty: A Long Term Follow-up. Clinical Medicine Research, 5(3), 20-23. https://doi.org/10.11648/j.cmr.20160503.11

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    ACS Style

    Jing Wang; Min Chen; Jiang Du. Effect of Conservative Treatment for Refracture in Cemented Vertebrae After Percutaneous Vertebroplasty: A Long Term Follow-up. Clin. Med. Res. 2016, 5(3), 20-23. doi: 10.11648/j.cmr.20160503.11

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    AMA Style

    Jing Wang, Min Chen, Jiang Du. Effect of Conservative Treatment for Refracture in Cemented Vertebrae After Percutaneous Vertebroplasty: A Long Term Follow-up. Clin Med Res. 2016;5(3):20-23. doi: 10.11648/j.cmr.20160503.11

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  • @article{10.11648/j.cmr.20160503.11,
      author = {Jing Wang and Min Chen and Jiang Du},
      title = {Effect of Conservative Treatment for Refracture in Cemented Vertebrae After Percutaneous Vertebroplasty: A Long Term Follow-up},
      journal = {Clinical Medicine Research},
      volume = {5},
      number = {3},
      pages = {20-23},
      doi = {10.11648/j.cmr.20160503.11},
      url = {https://doi.org/10.11648/j.cmr.20160503.11},
      eprint = {https://article.sciencepublishinggroup.com/pdf/10.11648.j.cmr.20160503.11},
      abstract = {By a long term follow-up, we evaluated the effects of conservative treatment for refracture of cemented vertebrae after percutaneous vertebroplasty (PVP). 12 patients of 324 patients who underwent PVP from January 2012 to August 2014, with back pain, were confirmed refracture in cemented vertebrae. 7 patients got conservative treatment: the usage of analgesics, osteoporosis medication, brace and physical therapy. Visual analogue seale (VAS) and Oswestry disability index (ODI) were evaluated at 7 days, 1, 3 and 12 months after treatment. Patients were followed up for 21.3 ± 11.2 months. Compared with that before treatment, VAS and ODI scores were significantly decreased after treatment (P  0.05). Further, there were no complications happened, such as leg phlebothrombosis, decubitus and hypostatic pneumonia. Thus, the results of our conservative treatment were optimal. Accordingly, the ratio of refracture in cemented vertebrae after PVP is low, but it is critical for back pain after PVP which should be pay enough attention for clinicians. Conservative treatment can relieve pain and improve spine function, without obvious complications.},
     year = {2016}
    }
    

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    AU  - Jing Wang
    AU  - Min Chen
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    Y1  - 2016/04/26
    PY  - 2016
    N1  - https://doi.org/10.11648/j.cmr.20160503.11
    DO  - 10.11648/j.cmr.20160503.11
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    AB  - By a long term follow-up, we evaluated the effects of conservative treatment for refracture of cemented vertebrae after percutaneous vertebroplasty (PVP). 12 patients of 324 patients who underwent PVP from January 2012 to August 2014, with back pain, were confirmed refracture in cemented vertebrae. 7 patients got conservative treatment: the usage of analgesics, osteoporosis medication, brace and physical therapy. Visual analogue seale (VAS) and Oswestry disability index (ODI) were evaluated at 7 days, 1, 3 and 12 months after treatment. Patients were followed up for 21.3 ± 11.2 months. Compared with that before treatment, VAS and ODI scores were significantly decreased after treatment (P  0.05). Further, there were no complications happened, such as leg phlebothrombosis, decubitus and hypostatic pneumonia. Thus, the results of our conservative treatment were optimal. Accordingly, the ratio of refracture in cemented vertebrae after PVP is low, but it is critical for back pain after PVP which should be pay enough attention for clinicians. Conservative treatment can relieve pain and improve spine function, without obvious complications.
    VL  - 5
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Author Information
  • Department of Orthopedics, the First Affiliated Hospital of Jinan University, Guangzhou, China

  • Department of Orthopedics, the First Affiliated Hospital of Jinan University, Guangzhou, China

  • Department of Orthopedics, the First Affiliated Hospital of Jinan University, Guangzhou, China

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