Haematological Profiles of Patients with Extra-pulmonary Tuberculosis
Clinical Medicine Research
Volume 9, Issue 1, January 2020, Pages: 20-24
Received: Aug. 11, 2019; Accepted: Oct. 23, 2019; Published: Feb. 18, 2020
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Authors
Silas Anayochukwu Ufelle, Department of Medical Laboratory Sciences, University of Nigeria Enugu Campus, Enugu, Nigeria
Kenechukwu Chibuike Onyekwelu, Department of Medical Biochemistry, University of Nigeria Enugu Campus, Enugu, Nigeria
Peter Uwadiegwu Achukwu, Department of Medical Laboratory Sciences, University of Nigeria Enugu Campus, Enugu, Nigeria
Augustine Chidi Ndubisi, Department of Medical Biochemistry, University of Nigeria Enugu Campus, Enugu, Nigeria
Richard Chukwunonye Ezeh, Department of Medical Biochemistry, ESUT College of Medicine, Parklane, Nigeria
Lorreta Nwakaego Nwokolo, Department of Medical Biochemistry, University of Nigeria Enugu Campus, Enugu, Nigeria
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Abstract
Tuberculosis (TB) is a disease caused by bacteria called Mycobacterium tuberculosis. We aimed to evaluate the complete blood count (CBC) and erythrocyte sedimentation rate (ESR) of confirmed extra-pulmonary tuberculosis (EPTB) patients attending clinic at the University of Nigeria Teaching Hospital (UNTH), Ituku-Ozalla, Enugu. A total of 90 confirmed extra-pulmonary tuberculosis patients consisting of male (n = 38) and female (n = 52), aged 15 to 60 years attending clinic participated in this study. CBC and ESR were analysed using Haematological Auto Analyzer and Westergren method respectively. Haemoglobin and haematocrit values across the three age groups (15-30, 31-45, 46-60 years) were significantly lower (p < 0.05) than the control value in both male and female extra-pulmonary tuberculosis patients. Erythrocyte sedimentation rate, white blood count, platelet and neutrophil values across the three were significantly higher (p < 0.05) than the control values in both male and female extra-pulmonary tuberculosis patients. Extra-pulmonary tuberculosis was observed more in females than the males and was relatively higher in older patients (above 46 years) than younger patients (below 46 years). This study was able to show that different haematological parameters such as haemoglobin, haematocrit, Erythrocyte sedimentation rate, white blood count, platelet and neutrophil could serve as hallmark and help in early diagnosis of extra-pulmonary tuberculosis.
Keywords
Extra-pulmonary Tuberculosis, Comzplete Blood Count, Erythrocyte Sedimentation Rate
To cite this article
Silas Anayochukwu Ufelle, Kenechukwu Chibuike Onyekwelu, Peter Uwadiegwu Achukwu, Augustine Chidi Ndubisi, Richard Chukwunonye Ezeh, Lorreta Nwakaego Nwokolo, Haematological Profiles of Patients with Extra-pulmonary Tuberculosis, Clinical Medicine Research. Vol. 9, No. 1, 2020, pp. 20-24. doi: 10.11648/j.cmr.20200901.14
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Copyright © 2020 Authors retain the copyright of this article.
This article is an open access article distributed under the Creative Commons Attribution License (http://creativecommons.org/licenses/by/4.0/) which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
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