The Correlation of Symptoms Severity and Objective Measures in Patients with Lower Urinary Tract Symptoms

Basri Cakiroglu; Ramazan Gozukucuk; Orhun Sinanoglu; Suleyman Hilmi Aksoy; Tuncay Tas; Seyit Erkan Eyyupoglu; Bekir Sami Uyanik

doi:doi:10.11648/j.cmr.20130206.14

The Correlation of Symptoms Severity and Objective Measures in Patients with Lower Urinary Tract Symptoms

Basri Cakiroglu, Ramazan Gozukucuk, Orhun Sinanoglu, Suleyman Hilmi Aksoy, Tuncay Tas, Seyit Erkan Eyyupoglu, Bekir Sami Uyanik

Published in Clinical Medicine Research (Volume 2, Issue 6)

Received: 11 September 2013 Accepted: Published: 20 October 2013

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Abstract

Purpose: To evaluate the correlation between international prostate symptom score (IPSS) and objective measures of lower urinary tract symptoms to estimate the grade of infravesical obstruction in benign prostatic hyperplasia (BPH). Methods: The data of 152 male patients examined in urology outpatient clinic with lower urinary tract symptoms (LUTS) were retrospectively rewieved between January 2010 and December 2011. Prostate volume, detrusor wall thickness (DWT) and post voiding residue (PVR) were evaluated with suprapubic ultrasound. The patients were distributed in three groups according to IPSS values; 1st, lower IPSS group (n=39), 2nd, moderate IPSS group (n=80) and 3rd, .higher IPSS group (n=33). IPSS, BWT, prostate volume, postvoiding residue (PVR), and maximum urine flow (Qmax) values were compared. Results: The mean age was 52.9 ±9.0 years. There were significant differences between the three groups for total PSA, in terms of prostate volume, DWT, PVR, Qmax, Qave values. There was a significant correlation between IPSS questionnaire results and PVR, Qmax and Qave (P< 0.05). PVR, Qmax and PVR values revealed especially strong positive correlations with symptoms severity or IPSS (Pearson /Spearman’s correlation coefficients were 0.441; p < 0.000 and 0.446; p < 0.000 respectively; Table 3). Conclusions: There are significant correlations between symptoms severity (IPSS) and objective BPH-related parameters, such as age, PSA, prostate volume, DWT, PVR, Qmax, Qave and QoL. The measurements of especially DWT, PVR and Qmax are promising noninvasive tools to predict the grade of LUTS in men and is reflected in IPSS severity.

Published in	Clinical Medicine Research (Volume 2, Issue 6)
DOI	10.11648/j.cmr.20130206.14
Page(s)	135-139
Creative Commons	This is an Open Access article, distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution and reproduction in any medium or format, provided the original work is properly cited.
Copyright	Copyright © The Author(s), 2024. Published by Science Publishing Group

Keywords

Uroflowmetry, Prostate Volume, PSA, IPSS, DWT, BPH, LUTS

References

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[2]	AUA Practice Guidelines Committee. AUA guideline on management of benign prostatic hyperplasia (2003). Chapter 1: diagnosis and treatment recommendations. J Urol, 2003. 170: p. 530-547.
[3]	Belal M, Abrams P. Noninvasive methods of diagnosing bladder outlet obstruction in men. Part 1. Non-urodynamic approach. J Urol, 2006. 176: p. 22–28.
[4]	Wang JY, et al., Relationship between lower urinary tract symptoms and objective measures of benign prostatic hyperplasia: a Chinese survey. Chin Med J (Engl), 2008. 20; 121(20): p. 2042-5.
[5]	Wu SL, et al., Natural history of benign prostatic hyperplasia. Chin Med J, 2006. 119: p. 2085-2089.
[6]	Barry MJ, et al., The American Urological Association symptom index for benign prostatic hyperplasia. The Measurement Committee of the American Urological Association. J Urol, 1992. 148: p. 1549-1557.
[7]	Madersbacher S, et al., Is obstruction predictable by clinical evaluation in patients with lower urinary tract symptoms? Br J Urol, 1997. 80: p. 72-77.
[8]	Kezzeldin LA, et al., Correlation between uroflowmetry, prostate volume, postvoid residue, and lower urinary tract symptoms as measured by the international prostate symptom score. Urology, 1996. 48: p. 393-397.
[9]	Tubaroa A, Vecchia CA. The relation of lower urinary tract symptoms with life-style factors and objective measures of benign prostatic enlargement and obstruction: an Italian survey. Eur Urol, 2004. 45: p. 767-772.
[10]	Wang JY, et al., Relationship between lower urinary tract symptoms and objective measures of benign prostatic hyperplasia: a Chinese survey Chin Med J, 2008. 121(20): p. 2042-2045
[11]	Tokgoz O, et al., Diagn Interv Radiol, 2012. 18: p. 277–281.
[12]	Li MK, et al., An Asian multinational prospective observational registry of patients with benign prostatic hyperplasia, with a focus on comorbidities, lower urinary tract symptoms and sexual function. BJU Int, 2008. 101: p. 197-202.
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[14]	Tubaro A, Miano L. Managing the consequences of obstruction. Eur Urol Suppl, 2002. 1: p. 21–27.
[15]	Oelke M, et al., Increase in detrusor wall thickness indicates bladder outlet obstruction (BOO) in men. World J Urol, 2002. 19: p. 443–452.
[16]	Levent Işıkay, et al., Lower urinary tract symptoms, prostate volume, uroflowmetry, residual urine volume and bladder wall thickness in Turkish men: a comparative analysis. Int Urol Nephrol, 2007. 39: p. 1131–1135.
[17]	Kessler TM, et al., Ultrasound assessment of detrusor thickness in men. Can it predict bladder outlet obstruction and replace pressure flow study? J Urol, 2006. 175: p. 2170–2173.

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APA Style

Basri Cakiroglu, Ramazan Gozukucuk, Orhun Sinanoglu, Suleyman Hilmi Aksoy, Tuncay Tas, et al. (2013). The Correlation of Symptoms Severity and Objective Measures in Patients with Lower Urinary Tract Symptoms. Clinical Medicine Research, 2(6), 135-139. https://doi.org/10.11648/j.cmr.20130206.14

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ACS Style

Basri Cakiroglu; Ramazan Gozukucuk; Orhun Sinanoglu; Suleyman Hilmi Aksoy; Tuncay Tas, et al. The Correlation of Symptoms Severity and Objective Measures in Patients with Lower Urinary Tract Symptoms. Clin. Med. Res. 2013, 2(6), 135-139. doi: 10.11648/j.cmr.20130206.14

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AMA Style

Basri Cakiroglu, Ramazan Gozukucuk, Orhun Sinanoglu, Suleyman Hilmi Aksoy, Tuncay Tas, et al. The Correlation of Symptoms Severity and Objective Measures in Patients with Lower Urinary Tract Symptoms. Clin Med Res. 2013;2(6):135-139. doi: 10.11648/j.cmr.20130206.14

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@article{10.11648/j.cmr.20130206.14,
  author = {Basri Cakiroglu and Ramazan Gozukucuk and Orhun Sinanoglu and Suleyman Hilmi Aksoy and Tuncay Tas and Seyit Erkan Eyyupoglu and Bekir Sami Uyanik},
  title = {The Correlation of Symptoms Severity and Objective Measures in Patients with Lower Urinary Tract Symptoms},
  journal = {Clinical Medicine Research},
  volume = {2},
  number = {6},
  pages = {135-139},
  doi = {10.11648/j.cmr.20130206.14},
  url = {https://doi.org/10.11648/j.cmr.20130206.14},
  eprint = {https://article.sciencepublishinggroup.com/pdf/10.11648.j.cmr.20130206.14},
  abstract = {Purpose: To evaluate the correlation between international prostate symptom score (IPSS) and objective measures of lower urinary tract symptoms to estimate the grade of infravesical obstruction in benign prostatic hyperplasia (BPH). Methods: The data of 152 male patients examined in urology outpatient clinic with lower urinary tract symptoms (LUTS) were retrospectively rewieved between January 2010 and December 2011. Prostate volume, detrusor wall thickness (DWT) and post voiding residue (PVR) were evaluated with suprapubic ultrasound. The patients were distributed in three groups according to IPSS values; 1st, lower IPSS group (n=39), 2nd, moderate IPSS group (n=80) and 3rd, .higher IPSS group (n=33). IPSS, BWT, prostate volume, postvoiding residue (PVR), and maximum urine flow (Qmax) values were compared. Results: The mean age was 52.9 ±9.0 years. There were significant differences between the three groups for total PSA, in terms of prostate volume, DWT, PVR, Qmax, Qave values. There was a significant correlation between IPSS questionnaire results and PVR, Qmax and Qave (P< 0.05). PVR, Qmax and PVR values revealed especially strong positive correlations with symptoms severity or IPSS (Pearson /Spearman’s correlation coefficients were 0.441; p < 0.000 and 0.446; p < 0.000 respectively; Table 3). Conclusions: There are significant correlations between symptoms severity (IPSS) and objective BPH-related parameters, such as age, PSA, prostate volume, DWT, PVR, Qmax, Qave and QoL. The measurements of especially DWT, PVR and Qmax are promising noninvasive tools to predict the grade of LUTS in men and is reflected in IPSS severity.},
 year = {2013}
}

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TY  - JOUR
T1  - The Correlation of Symptoms Severity and Objective Measures in Patients with Lower Urinary Tract Symptoms
AU  - Basri Cakiroglu
AU  - Ramazan Gozukucuk
AU  - Orhun Sinanoglu
AU  - Suleyman Hilmi Aksoy
AU  - Tuncay Tas
AU  - Seyit Erkan Eyyupoglu
AU  - Bekir Sami Uyanik
Y1  - 2013/10/20
PY  - 2013
N1  - https://doi.org/10.11648/j.cmr.20130206.14
DO  - 10.11648/j.cmr.20130206.14
T2  - Clinical Medicine Research
JF  - Clinical Medicine Research
JO  - Clinical Medicine Research
SP  - 135
EP  - 139
PB  - Science Publishing Group
SN  - 2326-9057
UR  - https://doi.org/10.11648/j.cmr.20130206.14
AB  - Purpose: To evaluate the correlation between international prostate symptom score (IPSS) and objective measures of lower urinary tract symptoms to estimate the grade of infravesical obstruction in benign prostatic hyperplasia (BPH). Methods: The data of 152 male patients examined in urology outpatient clinic with lower urinary tract symptoms (LUTS) were retrospectively rewieved between January 2010 and December 2011. Prostate volume, detrusor wall thickness (DWT) and post voiding residue (PVR) were evaluated with suprapubic ultrasound. The patients were distributed in three groups according to IPSS values; 1st, lower IPSS group (n=39), 2nd, moderate IPSS group (n=80) and 3rd, .higher IPSS group (n=33). IPSS, BWT, prostate volume, postvoiding residue (PVR), and maximum urine flow (Qmax) values were compared. Results: The mean age was 52.9 ±9.0 years. There were significant differences between the three groups for total PSA, in terms of prostate volume, DWT, PVR, Qmax, Qave values. There was a significant correlation between IPSS questionnaire results and PVR, Qmax and Qave (P< 0.05). PVR, Qmax and PVR values revealed especially strong positive correlations with symptoms severity or IPSS (Pearson /Spearman’s correlation coefficients were 0.441; p < 0.000 and 0.446; p < 0.000 respectively; Table 3). Conclusions: There are significant correlations between symptoms severity (IPSS) and objective BPH-related parameters, such as age, PSA, prostate volume, DWT, PVR, Qmax, Qave and QoL. The measurements of especially DWT, PVR and Qmax are promising noninvasive tools to predict the grade of LUTS in men and is reflected in IPSS severity.
VL  - 2
IS  - 6
ER  -

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Author Information

Basri Cakiroglu

Hisar Intercontinental Hospital, Department of Urology, 34768 Umraniye, Istanbul, Turkey
Ramazan Gozukucuk

Hisar Intercontinental Hospital, Department of Infectious and Clinical Microbiology, 34768 Umraniye, Istanbul, Turkey
Orhun Sinanoglu

Maltepe University, Medical School Department of Urology, 34857 Maltepe, Istanbu,Turkey
Suleyman Hilmi Aksoy

Hisar Intercontinental Hospital, Department of Radiology, 34768 Umraniye, Istanbul,Turkey
Tuncay Tas

Taksim Training and Research Hospital, Department of Urology, 34433 Taksim, Istanbul, Turkey
Seyit Erkan Eyyupoglu

Sabuncuoglu Serefettin Training and Research Hospital, Department of Urology, 05200 Amasya, Turkey
Bekir Sami Uyanik

Hisar Intercontinental Hospital, Department of Clinical Biochemistry, 34768 Umraniye, Istanbul, Turkey

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APA Style

Basri Cakiroglu, Ramazan Gozukucuk, Orhun Sinanoglu, Suleyman Hilmi Aksoy, Tuncay Tas, et al. (2013). The Correlation of Symptoms Severity and Objective Measures in Patients with Lower Urinary Tract Symptoms. Clinical Medicine Research, 2(6), 135-139. https://doi.org/10.11648/j.cmr.20130206.14

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ACS Style

Basri Cakiroglu; Ramazan Gozukucuk; Orhun Sinanoglu; Suleyman Hilmi Aksoy; Tuncay Tas, et al. The Correlation of Symptoms Severity and Objective Measures in Patients with Lower Urinary Tract Symptoms. Clin. Med. Res. 2013, 2(6), 135-139. doi: 10.11648/j.cmr.20130206.14

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AMA Style

Basri Cakiroglu, Ramazan Gozukucuk, Orhun Sinanoglu, Suleyman Hilmi Aksoy, Tuncay Tas, et al. The Correlation of Symptoms Severity and Objective Measures in Patients with Lower Urinary Tract Symptoms. Clin Med Res. 2013;2(6):135-139. doi: 10.11648/j.cmr.20130206.14

Copy | Download

@article{10.11648/j.cmr.20130206.14,
  author = {Basri Cakiroglu and Ramazan Gozukucuk and Orhun Sinanoglu and Suleyman Hilmi Aksoy and Tuncay Tas and Seyit Erkan Eyyupoglu and Bekir Sami Uyanik},
  title = {The Correlation of Symptoms Severity and Objective Measures in Patients with Lower Urinary Tract Symptoms},
  journal = {Clinical Medicine Research},
  volume = {2},
  number = {6},
  pages = {135-139},
  doi = {10.11648/j.cmr.20130206.14},
  url = {https://doi.org/10.11648/j.cmr.20130206.14},
  eprint = {https://article.sciencepublishinggroup.com/pdf/10.11648.j.cmr.20130206.14},
  abstract = {Purpose: To evaluate the correlation between international prostate symptom score (IPSS) and objective measures of lower urinary tract symptoms to estimate the grade of infravesical obstruction in benign prostatic hyperplasia (BPH). Methods: The data of 152 male patients examined in urology outpatient clinic with lower urinary tract symptoms (LUTS) were retrospectively rewieved between January 2010 and December 2011. Prostate volume, detrusor wall thickness (DWT) and post voiding residue (PVR) were evaluated with suprapubic ultrasound. The patients were distributed in three groups according to IPSS values; 1st, lower IPSS group (n=39), 2nd, moderate IPSS group (n=80) and 3rd, .higher IPSS group (n=33). IPSS, BWT, prostate volume, postvoiding residue (PVR), and maximum urine flow (Qmax) values were compared. Results: The mean age was 52.9 ±9.0 years. There were significant differences between the three groups for total PSA, in terms of prostate volume, DWT, PVR, Qmax, Qave values. There was a significant correlation between IPSS questionnaire results and PVR, Qmax and Qave (P< 0.05). PVR, Qmax and PVR values revealed especially strong positive correlations with symptoms severity or IPSS (Pearson /Spearman’s correlation coefficients were 0.441; p < 0.000 and 0.446; p < 0.000 respectively; Table 3). Conclusions: There are significant correlations between symptoms severity (IPSS) and objective BPH-related parameters, such as age, PSA, prostate volume, DWT, PVR, Qmax, Qave and QoL. The measurements of especially DWT, PVR and Qmax are promising noninvasive tools to predict the grade of LUTS in men and is reflected in IPSS severity.},
 year = {2013}
}

Copy | Download

TY  - JOUR
T1  - The Correlation of Symptoms Severity and Objective Measures in Patients with Lower Urinary Tract Symptoms
AU  - Basri Cakiroglu
AU  - Ramazan Gozukucuk
AU  - Orhun Sinanoglu
AU  - Suleyman Hilmi Aksoy
AU  - Tuncay Tas
AU  - Seyit Erkan Eyyupoglu
AU  - Bekir Sami Uyanik
Y1  - 2013/10/20
PY  - 2013
N1  - https://doi.org/10.11648/j.cmr.20130206.14
DO  - 10.11648/j.cmr.20130206.14
T2  - Clinical Medicine Research
JF  - Clinical Medicine Research
JO  - Clinical Medicine Research
SP  - 135
EP  - 139
PB  - Science Publishing Group
SN  - 2326-9057
UR  - https://doi.org/10.11648/j.cmr.20130206.14
AB  - Purpose: To evaluate the correlation between international prostate symptom score (IPSS) and objective measures of lower urinary tract symptoms to estimate the grade of infravesical obstruction in benign prostatic hyperplasia (BPH). Methods: The data of 152 male patients examined in urology outpatient clinic with lower urinary tract symptoms (LUTS) were retrospectively rewieved between January 2010 and December 2011. Prostate volume, detrusor wall thickness (DWT) and post voiding residue (PVR) were evaluated with suprapubic ultrasound. The patients were distributed in three groups according to IPSS values; 1st, lower IPSS group (n=39), 2nd, moderate IPSS group (n=80) and 3rd, .higher IPSS group (n=33). IPSS, BWT, prostate volume, postvoiding residue (PVR), and maximum urine flow (Qmax) values were compared. Results: The mean age was 52.9 ±9.0 years. There were significant differences between the three groups for total PSA, in terms of prostate volume, DWT, PVR, Qmax, Qave values. There was a significant correlation between IPSS questionnaire results and PVR, Qmax and Qave (P< 0.05). PVR, Qmax and PVR values revealed especially strong positive correlations with symptoms severity or IPSS (Pearson /Spearman’s correlation coefficients were 0.441; p < 0.000 and 0.446; p < 0.000 respectively; Table 3). Conclusions: There are significant correlations between symptoms severity (IPSS) and objective BPH-related parameters, such as age, PSA, prostate volume, DWT, PVR, Qmax, Qave and QoL. The measurements of especially DWT, PVR and Qmax are promising noninvasive tools to predict the grade of LUTS in men and is reflected in IPSS severity.
VL  - 2
IS  - 6
ER  -

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