Effectiveness of Psychiatric Nursing Intervention on Adherence to Medications and Quality of Life of Schizophrenic Patients
American Journal of Nursing Science
Volume 5, Issue 6, December 2016, Pages: 232-239
Received: Sep. 22, 2016; Accepted: Oct. 5, 2016; Published: Nov. 3, 2016
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Authors
Sabah Mohamed Ebrahem, Department of Psychiatric Nursing, Menofia University, Cairo, Egypt
Faten Hasan Alam, Department of Psychiatric Nursing, Menofia University, Cairo, Egypt
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Abstract
Medication adherence is a key determinant of the success of pharmacotherapy in patients with schizophrenia and can have an impact on the quality of life. The aim of the study was to evaluate the effect of a psychiatric nursing intervention on adherence to medications and quality of life of schizophrenic patients. A Quasi-experimental design (one group pretest-posttest) was used. The study was conducted at Outpatient Clinics of The Psychiatric and Addiction Treatment Hospital in MIT-Khalaf at Menoufia, Egypt. Non-probability sampling of 50 schizophrenic patients from the previously mentioned setting was recruited. Tools of the study include a structured interview questionnaire, the Medication Adherence Rating Scale and The world health organization quality of life (WHOQOL-BRIEF) scale. The study illustrated that, there was a statistically significant improvement in attitude toward medication and quality of life of patients with schizophrenia after implementation of a psychiatric nursing intervention. In conclusion: the psychiatric nursing intervention was effective in improvement of medication adherence and quality of life of schizophrenic patients. So, it was recommended that, the psychiatric hospital should utilize educational programs to all psychiatric inpatients and outpatients to improve their awareness about their disorder and their medications to improve their adherence and quality of life.
Keywords
Medication Adherence, Quality of Life, Schizophrenia
To cite this article
Sabah Mohamed Ebrahem, Faten Hasan Alam, Effectiveness of Psychiatric Nursing Intervention on Adherence to Medications and Quality of Life of Schizophrenic Patients, American Journal of Nursing Science. Vol. 5, No. 6, 2016, pp. 232-239. doi: 10.11648/j.ajns.20160506.11
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Copyright © 2016 Authors retain the copyright of this article.
This article is an open access article distributed under the Creative Commons Attribution License (http://creativecommons.org/licenses/by/4.0/) which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
References
[1]
ABC Project Team. (2014). Ascertaining barriers for compliance: policies for safe, effective and cost-effective use of medicines in Europe. Final report of the ABC project. Available from: http://abcproject.eu/img/ABC%20Final.pdf.
[2]
Fraser S. (2010).Concordance, compliance, preference or adherence. Patient Prefer Adherence.;4:95–6
[3]
Adelufosi, O., Adebowale, O., Abayomi, A., Mosanya, T. (2012). Medication adherence and quality of life among Nigerian outpatients with schizophrenia, General Hospital Psychiatry ;(34): 72-79
[4]
Mueser, K. T., Deavers, F., Penn, D. L., Cassisi, J. E. (2013). Psychosocial treatments for schizophrenia. Annu Rev Clin Psychol;9:465–497
[5]
Kane J. M. (2007). Treatment strategies to prevent relapse and encourage remission. J. Clin. Psychiatry; 68: 27-30
[6]
Morken G., Widen J. H., and Grawe R. W. (2008). Non-adherence to antipsychotic medication, relapse and rehospitalisation in recent-onset schizophrenia. BMC Psychiatry; 8:. 32
[7]
Galuppi A., Turola M. C., and Mazzoni P. (2012). Quality of life and personal and social functioning: new targets in schizophrenia treatment. In Sumiyoshi T. (eds): Schizophrenia Research: Recent Advances. Hauppauge, NY, USA: Nova Science Publishers; 45-59
[8]
Gaebel, W.(2011). Schizophrenia: Current Science and Clinical Practice. Hoboken, New Jersey, USA: Wiley-Blackwell.
[9]
APA Task Force on Evidence-Based Practice. (2006). Evidence-based practice in psychology. American Psychologist, 61, 271–285.
[10]
American Society on Aging, American Society of Consultant Pharmacists. (2011). Adult medication: overview of medication adherence. Available at: www.adultmeducation.com/OverviewofMedicationAdherence.html.
[11]
Magura, S., Rosenblum, A., Fong, C. (2011). Factors associated with medication adherence among psychiatric outpatients at substance abuse risk. Open Addiction Journal; 4: 58–64.
[12]
Lee, C. (2013). Improving medication adherence in patients with severe mental illness. Pharmacy Today.;19(6):69-80
[13]
Barcaccia, Barbara (2013). "Quality Of Life: Everyone Wants It, But What Is It?". Forbes/ Education. Retrieved 10 May 2016
[14]
Franz M. (2006). Possibilities and limitations of the use of quality of life as outcome-indicator in schizophrenic patients. Psychiatr Prax. ; 33(7):317-22.
[15]
Elmasri., Y. (2011). Effect of Educational Program on Insight into Illness and Attitudes toward Medications among Schizophrenic Patients. Journal of American Science; 7(3).
[16]
World Health Organization. (2013). Adherence to long-term therapies: evidence for action. Accessed at www.who.int/chp/knowledge/publications/adherence_full_report.pdf.
[17]
Bisbee, C., and Vickar, M. (2012). A Review of Psycho-education for Patients with Schizophrenia. Psychiatric Annals.; 42(6): 205-210
[18]
World Health Organization (WHO). (2014).Mental health, Available at:http://www.who.int/mental_health/management/schizophrenia/en/.
[19]
Bruijnzeel, D. and Tandon, R. (2011).The Concept of Schizophrenia: From the 1850s to the DSM-5. Psychiatr. Ann; 41: 289–295
[20]
Kassis,T., Ghuloum, S., Mousa, H., and Bener, A. (2014).Treatment non-compliance of psychiatric patients; are patients satisfied from their psychiatrist? British Journal of Medicine and Medical Research; 4(2): 785–796
[21]
Higashi, K., Medic, G., Littlewood, J., Diez, T and Granström, O. (2013). Medication adherence in schizophrenia: factors influencing adherence and consequences of nonadherence, a systematic literature review. Ther Adv Psychopharmacol; 3: 200–218
[22]
Kenfe, T., Girma, E., Negash, A., Tesfaye, M and Dehning, S.( 2013). Medication non-adherence among adult psychiatric outpatients in Jimma University Specialized Hospital, southwest Ethiopia. Ethiop J Health Sci.; 23(3): 227–236
[23]
Center for Health Transformation. (2013). The 21st Century Intelligent Pharmacy Project: the importance of medication adherence. Accessed at www.mirixa.com/uploads/pdfs/CHTMedAdhrWp.pdf.
[24]
Adelufosi, O., Ogunwale, A., Abayomi, O. and Mosanya, T. (2013).Socio-demographic and clinical correlates of subjective quality of life among Nigerian outpatients with schizophrenia. Psychiatry Res;209: 320–325
[25]
WHO. (2008). Policies and practices for mental health in Europe – meeting the challenges. World Health Organization, Regional Office for Europe, Copenhagen, Denmark.
[26]
Thompson, K., Kulkarni, et al. (2000). Reliability and validity of a new Medication Adherence Rating Scale (MARS) for the psychoses. Schizophrenia Research; 42: 241-247.
[27]
Skevington, S., Lotfy, M and O’Connell, K. (2004).The World Health Organization’s WHOQOL-BREF quality of life assessment: Psychometric properties and results of the international field trial A Report from the WHOQOL Group. Quality of Life Research; 13: 299–310
[28]
British Medical Association. (2010). British National Formulary (60). BMJ Publishing Group Ltd., RPS Publishing, London
[29]
Aldridge., M. (2011). Addressing non-adherence to antipsychotic medication: a harm-reduction approach. Journal of Psychiatric and Mental Health Nursing; 1:12
[30]
Barkhof, E., Meijer, J., Sonneville,. M., Linszen, H., and Haan, L. (2012). Interventions to improve adherence to antipsychotic medication in patients with schizophrenia: A review of the past decade. European Psychiatry; 27: 9–18.
[31]
Dibonaventura M, Gabriel S, Dupclay L, et al. (2012). A patient perspective of the impact of medication side effects on adherence: results of a cross-sectional nationwide survey of patients with schizophrenia. BMC Psychiatry;12:20
[32]
Dassa D, Boyer L, Benoit M, et al. (2010). Factors associated with medication non-adherence in patients suffering from schizophrenia: a cross-sectional study in a universal coverage health-care system. Aust N Z J Psychiatry; 44: 921–8
[33]
Yang J, Ko YH, Paik JW, et al. (2012).Symptom severity and attitudes toward medication: impacts on adherence in outpatients with schizophrenia. Schizophr Res; 134(23):226–31.
[34]
Kamali M., Kelly D, Clarke M., et al. (2006). A prospective evaluation of adherence to medication in first episode schizophrenia. Eur Psychiatry; 21: 29–33.
[35]
Ran, M., Xiang, C., Chan, J., Leff, P., Simpson,M., and Huang, L. (2003). Effectiveness of psycho educational intervention for rural Chinese families experiencing schizophrenia: A randomized controlled trial. Social Psychiatry; 38: 69-75
[36]
Chaiyajan, Y., Sitthimongkol, Y., and P. Klainin, (2009). Effects of Psycho Educational Program on Attitude toward Medication and Compliance with First Appointment after Discharge in Schizophrenic Patients. Journal of Nursing Science; 27: 73-81.
[37]
Dsouza R, Piskulic D, Sundram S, et al. (2010). A brief dyadic group based psycho-education program improves relapse rate in recently remitted bipolar disorder: a pilot randomized controlled trial. Journal of Affective Disorder; 120: 272–6
[38]
Baruah, A., and Reddemma, K. (2012). Effectiveness of educative intervention on drug compliance for patients with schizophrenia. Dysphrenia; 3: 74-79.
[39]
Puschner, B., Born, A., Giessler, A., Giebler, A., Helm H, Leese M, Bindman JP, Gray RJ, Schene A, Kikkert, M., Burti, L., Marrella, G and Becker, T. (2006). Adherence to medication and quality of life in people with schizophrenia: results of a European multicenter study. J. Nerv. Ment. Dis; 194 (10); 746-52
[40]
Mitchell, J and Selmes, T. (2007). Why don't patients attend their appointments? Maintaining engagement with psychiatric services. Adv Psychiatr. Treat; 13:423–34.
[41]
Puschner B, Angermeyer C, Graham L, Schene A, Kikkert, M., and Burti, L., et al. (2009). Course of adherence to medication and quality of life in people with schizophrenia. Psychiatry Res; 165: 224–33
[42]
Vreeland, B., Minsky, S., Yanos, T., Menza, M., Gara, M., Kim, E., Toto, M., and Allen, L. (2006). Efficacy of the team solutions program for educating patients about illness management and treatment. Psychiatric Services; 57: 822-828.
[43]
Huang.J, Sadetsky N. Penson.. F. (2010) .Health related quality of life for men treated for localized prostate cancer with long-term follow up, J Urol; 183: 2206–2212
[44]
Krok,L., Baker, A., McMillan C.(2013).Age differences in the presence of pain and psychological distress in younger and older cancer patients. J Hosp Palliat Nurs; 15: 107–113
[45]
Mahler C, Hermann K, Horne R, et al. (2010). Assessing reported adherence to pharmacological treatment recommendations: translation and evaluation of the Medication Adherence Report Scale (MARS) in Germany. J Eval Clin Pract; 16(3): 574–9
[46]
World Health Organization. (2013). Adherence to long-term therapies evidence for action. Accessed at www.who.int/chp/knowledge/ publications/adherence_full_report.
[47]
Sari P., Suttharangsee,W., and Chanchong, W. (2014). The effect of self-management with family participation on medication adherence among patients with schizophrenia in Indonesia: A pilot study. Songklanagarind Journal of Nursing; (34): 12-24
[48]
Kulhara P., Chakrabarti S., Avasthi A., Sharma A., and Sharma S. (2009). Psycho-educational intervention for caregivers of Indian patients with schizophrenia: a randomized-controlled trial. Acta Psychiatry Scand.; 119: 472-483
[49]
Leclerc E, Mansur, R. B., Brietzke, E. (2013). Determinants of adherence to treatment in bipolar disorder: a comprehensive review; J Affect Disord; 149(13): 247-52.
[50]
Cutler M, Everett W. (2010). Thinking outside the pillbox: medication adherence as a priority for health care reform; 362 (17): 1553-1555.
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