Antioxidant/Anti-Inflammatory Activities and Chemical Composition of Extracts from the Mushroom Trametes Versicolor
International Journal of Nutrition and Food Sciences
Volume 2, Issue 2, March 2013, Pages: 85-91
Received: Apr. 9, 2013; Published: Mar. 10, 2013
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Masumi Kamiyama, Department of Environmental Toxicology, University of California, Davis, CA 95616, USA
Takayuki Shibamoto, Department of Environmental Toxicology, University of California, Davis, CA 95616, USA
Masahiro Horiuchi, Takata Koryo Co. Ltd., 7-22-2 Tsukaguchihonmachi, Amagasaki-Shi, Hyogo, 661-0001 Japan
Katsumi Umano, Takata Koryo Co. Ltd., 7-22-2 Tsukaguchihonmachi, Amagasaki-Shi, Hyogo, 661-0001 Japan
Kazuo Kondo, Institute of Environmental Science for Human Life, Ochanomizu University, Bunkyo-ku, Tokyo, 112-8610 Japan
Yuzuru Otsuka, Institute of Environmental Science for Human Life, Ochanomizu University, Bunkyo-ku, Tokyo, 112-8610 Japan
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The mushroom, Trametes versicolor is commonly used as a traditional Chinese medicine and is known to exhibit various biological activities. However, its antioxidant activity has remained unknown. In the present study, various extracts obtained from the Trametes versicolor mushroom were examined for antioxidant and anti-inflammatory activities. Among the extracts obtained with Soxhlet extraction, the extract from acetone exhibited the highest antioxidant activity (50.9%), followed by the extracts from methanol (33.9%), n-hexane (29.5%), and chloroform (15.2%) at the level of 500 g/mL. This acetone fraction displayed a dose-dependent anti-inflammatory activity or lipoxygenase inhibitory activity by 76.4% at 500 µg/mL, 55.6% at 200 µg/mL, and 37.0% at 100 µg/mL. Among a total of 76 compounds identified in this acetone extract, hexadecanoic acid was the largest component (18.11 mg/kg), followed by 5-hydroxy-2-pentanone (17.33 mg/kg), lactic acid (3.25 mg/kg), and acetic acid (3.21 mg/kg). The following possible principles of antioxidant activity were identified: furfural (1.48 mg/kg), -butyrolactone (0.51 mg/kg), furfuryl alcohol (0.49 mg/kg), 2-methoxy-4-vinylphenol (0.49 mg/kg), and 2,6-dimetoxy-4-vinylphenol (0.33 mg/kg), and benzaldehyde (0.15 mg/kg).
Trametes Versicolor Mushroom, Medicinal Plants, Antioxidant, Anti-Inflammatory, Lipoxygenase Inhibitor
To cite this article
Masumi Kamiyama, Takayuki Shibamoto, Masahiro Horiuchi, Katsumi Umano, Kazuo Kondo, Yuzuru Otsuka, Antioxidant/Anti-Inflammatory Activities and Chemical Composition of Extracts from the Mushroom Trametes Versicolor, International Journal of Nutrition and Food Sciences. Vol. 2, No. 2, 2013, pp. 85-91. doi: 10.11648/j.ijnfs.20130202.19
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