International Journal of Nutrition and Food Sciences
Volume 2, Issue 4, July 2013, Pages: 196-199
Received: Jun. 17, 2013;
Published: Jul. 20, 2013
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Antonelli F., University of Rome “Tor Vergata” Department of Biology, Rome, Italy
Ferorelli P., University of Rome “Tor Vergata” Department of Biology, Rome, Italy ; IURS Santa Rita, Rome, Italy
De Martino A., IURS Santa Rita, Rome, Italy
Beninati S., University of Rome “Tor Vergata” Department of Biology, Rome, Italy
The level of alcohol in the blood is a problem not only for health but also for motorists during the driving. The search for dietary supplements capable of reducing the rate of alcohol was hectic and different products with dubious quality have been put on the market. In the present work, 60 healthy male individuals were subjected to two tests. The first included the administration of 15 mL of concentrated commercial mixture of vitamins and antioxidants called Citoethyl (CTH), 40 minutes prior drinking 80 mL of pure ethyl alcohol diluted in 200 mL of water. The second test was performed by administering 15 mL of concentrated CTH, 40 minutes after drinking 80 mL of pure ethyl alcohol diluted in 200 mL of water. The amount of alcohol ingested corresponded to 1600 mL of beer ( 5% v/v alcohol) or 535 mL of wine (15% v / v alcohol) or 200 mL of liquor (40% v / v alcohol). The breath alcohol test was performed on each individual in six ranges of time from the administration of alcohol. We report in this work that there is a net reduction of the breath test value for alcohol resulting from the intake of CTH, in all the conditions used for experimentation. Not guaranteeing the results presented for higher doses of alcohol and for a too short period of time of administration of the CTH. The present work does not pretend to suggest a product for making drunk driving safer, but simply reports the experimental data on a mixture of vitamins and antioxidants, that show its qualities in reducing the rate of breath alcohol levels in healthy subjects.
De Martino A.,
Reduction of Breath Alcohol Levels in Healthy Subjects by Citoethyl, International Journal of Nutrition and Food Sciences.
Vol. 2, No. 4,
2013, pp. 196-199.
Guenther RM. Role of nutritional therapy in alcoholism treatment. Int J Biosoc Res 1983;4:5–18.
Biery JR, Williford JH & McMullen EA. Alcohol craving in rehabilitation: assessment of nutrition therapy. J Am Diet Assoc 1991;91:463–466.
Cleary JP. Etiology and biological treatment of alcohol addiction. J Neuro Ortho Med Surg 1985;6:75–77.
Smith RF. A five-year field trial of massive nicotinic acid therapy of alcoholics in Michigan. J Orthomolec Psychiatry 1974;3:327–331.
O’Halloren P. Pyridine nucleotides in the prevention, diagnosis and treatment of problem drinkers. West J Surg Obstet Gynecol 1961;69:101–104.
Cosmetic Ingredient Review Expert Panel. "Final report of the safety assessment of niacinamide and niacin." Int J Toxicol. 2005;24 Suppl 5:1-31.
Eriksson CJP. Increase in hepatic NAD level its effect on the redox state and on ethanol and acetaldehyde metabolism. Fed Eur Biochem Soc 1974;40:3117–3120.
Baker H. A vitamin profile of alcoholism. Int J Vitam Nutr Res 1983;(suppl 24):179.
Schuckit MA. Alcohol and Alcoholism. In: Fauci AS, Braunwald E, Isselbacher KJ, et al, eds, Harrison’s Principles of Internal Medicine, 14th ed. New York: McGraw-Hill, 1998, 2503–2508.
Norton VP. Interrelationships of nutrition and voluntary alcohol consumption in experimental animals. Br J Addiction 1977;72:205–212.
Morgan MY & Levine JA. Alcohol and nutrition. Proc Natl Acad Sci 1988;47:85–98.
Chapman K, Prabhudesai M, Erdman JW. Vitamin A status of alcoholics upon admission and after two weeks of hospitalization. J Am Coll Nutr 1993;12:77–83.
Leo MA & Lieber CS. Alcohol, vitamin A, and beta-carotene: adverse interactions, including hepatotoxicity and carcinogenicity. Am J Clin Nutr 1999;69:1071–1085 [review].
Chen M, Boyce W & Hsu JM. Effect of ascorbic acid on plasma alcohol clearance. J Am Coll Nutr 1990;9:185–189.
Yuma-Guerrero PJ, Lawson KA, Velasquez MM, von Sternberg K, Maxson T & Garcia N. Screening, brief intervention, and referral for alcohol use in adolescents: a systematic review.Pediatrics. 2012 ;130(1):115-122.
Frezza M, DiPadova C, Pozzato G, Terpin M, Baraona E & Lieber CS High blood alcohol levels in women: The role of decreased gastric alcohol dehydrogenase and first-pass metabolism. New England J Medicine 1990:322(2):95-99.
Heil SH, Hungund BL, Zheng ZH, Jen KL & Subramanian MG. Ethanol and lactation: Effects of milk lipids and serum constituents. Alcohol 1999; 18: 43-48.
Mennella JA & Pepino MY. Breastfeeding and prolactin levels in lactating women with a family history of alcoholism. Pediatrics. 2010;125(5):e1162-1170.
Pearson RM, Heron J, Melotti R, Joinson C & Evans J. The impact of alcohol use during pregnancy on maternal responses after birth. Arch Womens Ment Health. 2012;15(6):433-443.
Bissett S, Wood S, Cox R, Scott D, & Cassell J. Calculating alcohol risk in a visualization tool for promoting healthy behavior. Patient Educ Couns. 2013:Jun 3. doi:pii: S0738-3991(13)00169-9.
Torricelli P., Ferorelli P., De Martino A., Antonelli F & Beninati S. The Influence of preventive multiple micronutrients supplementation on Liver Steatosis in High-Cholesterol Fed C57BL6/N mice. American Journal of Life Sciences. 2013: 1(2);55-60.