Milk Consumption is Not Affected by C/T-13910 Single Nucleotide Polymorphism in a Tajik Population in a Southern Region of Uzbekistan
International Journal of Nutrition and Food Sciences
Volume 2, Issue 6, November 2013, Pages: 332-336
Received: Dec. 4, 2013; Published: Dec. 30, 2013
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Authors
Sharaf Kasimov, Department of Continuing Medical Education for General Practitioners of the Tashkent Institute of Postgraduate Medical Education, Uzbekistan
Margus Lember, Department of Internal Medicine, University of Tartu and University Hospital, Tartu, Estonia
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Abstract
Objective: To determine the prevalence of adult-type hypolactasia in the Tajik population living in the south of Uzbekistan by genotyping of allelic variants C/T-13910 and identifying their tolerance to milk. Methods: 100 ethnic Tajik adults were examined for C/T-13910 single nucleotide polymorphisms using polymerase chain reaction/restriction fragment length polymorphism. Milk tolerance was analyzed by a questionnaire developed to assess dyspepsia after milk and dairy consumption. Results: A genetic marker of hypolactasia - C/C-13910 genotype was detected in 83% of the adult Tajik population. However, despite the high prevalence of lactose intolerance in the Tajik population, the majority consume between 100-200 ml of milk per day. Conclusion: The Tajik population is characterized by a high prevalence of hypolactasia. Milk consumption is not affected by the determined genotypes since people of Tajik ethnicity consume milk in small quantities.
Keywords
Hypolactasia, Milk Consumption, Tajik Population
To cite this article
Sharaf Kasimov, Margus Lember, Milk Consumption is Not Affected by C/T-13910 Single Nucleotide Polymorphism in a Tajik Population in a Southern Region of Uzbekistan, International Journal of Nutrition and Food Sciences. Vol. 2, No. 6, 2013, pp. 332-336. doi: 10.11648/j.ijnfs.20130206.21
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