What is a Bioactive Compound? A Combined Definition for a Preliminary Consensus

Abdelkarim GUAADAOUI; Soumaya BENAICHA; Naima ELMAJDOUB; Mohammed BELLAOUI; Abdellah HAMAL

doi:doi:10.11648/j.ijnfs.20140303.16

| Peer-Reviewed

What is a Bioactive Compound? A Combined Definition for a Preliminary Consensus

Abdelkarim GUAADAOUI, Soumaya BENAICHA, Naima ELMAJDOUB, Mohammed BELLAOUI, Abdellah HAMAL

Published in International Journal of Nutrition and Food Sciences (Volume 3, Issue 3)

Received: 1 January 2014 Accepted: 7 May 2014 Published: 20 May 2014

Views: Downloads:

Download PDF

Share This Article

Twitter
Linked In
Facebook

Abstract

The definition of "bioactive compound" knowdynamism, because the scientific research on the bioactivity potential is booming nowadays. And since there is no unifying definition, attempts to find a consensus and some common elements of the concept associated with the term "bioactive" did not stop, even if vague definitions and repeated use of the operative word "bioactive" almost integrated the term in a category of magic words! This paper tried to find a combined definition which can be a platform to develop the "bioactive" concept, and reach a solid consensus on the term "bioactive compound". We use, for the first time, the term of "biocompounactive" tomore simplify the use of bioactive compound in relation with their physicochemical and biological properties.

Published in	International Journal of Nutrition and Food Sciences (Volume 3, Issue 3)
DOI	10.11648/j.ijnfs.20140303.16
Page(s)	174-179
Creative Commons	This is an Open Access article, distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution and reproduction in any medium or format, provided the original work is properly cited.
Copyright	Copyright © The Author(s), 2024. Published by Science Publishing Group

Keywords

Bioactive Compound, Biocompounactive, Secondary Metabolites, Phytochemicals, Food Components, Healthy Diet

References

[1]	Bernard G and DromardA; Book of etymology and medical terminology: Lexicon etymology (in French). Livretd’étymologieet de terminologiemédicale: Lexiqued’étymologie, 2011: 1-4.
[2]	Alain R ; Le Robert micro-poche (2nd Ed) (in french). 1994: 14 and 126.
[3]	Online Etymology Dictionary (website): http://www.etymonline.com; 2013.
[4]	Anonymous ; Larousse de poche (in french), Les Editions Françaises Inc. 1994 : 8.
[5]	Cammack R et al.; Oxford Dictionary of Biochemistry and Molecular Biology (2nd Ed). Oxford University Press, 2006: 74-75.
[6]	Dictionary of Food Science and Technology (2nd Ed). International Food Information Service (IFIS Editor), 2009: 47-48.
[7]	The American Heritage Medical Dictionary. Houghton Mifflin Company, 2007: 47.
[8]	Mosby's Dictionary of Medicine, Nursing and Health Professions (9th Ed). Mosby Creator, 2013: 83.
[9]	Miller-Keane and Marie TO; Miller-Keane Encyclopedia and Dictionary of Medicine, Nursing and Allied Health (7th Ed). Saunders, 2005: 62.
[10]	Bioactive compounds, Food Bioactives Centre, University of Gothenburg (website): http://www.chalmers.se/chem/fbac-en2012.
[11]	AkselB; A brief review on bioactive compounds in plants. In: Bioactive compounds in plants - benefits and risks for man and animals. Oslo: The Norwegian Academy of Science and Letters, 2010: 11-17.
[12]	Kris-Etherton PM and al.;Bioactive compounds in nutrition and health-research methodologies for establishing biological function: the antioxidant and anti-inflammatory effects of flavonoids on atherosclerosis. Annual Review of Nutrition, 2004, 24: 511-538.
[13]	Richard JW; Non-nutritional uses of nutrients. European Journal of Pharmacology, 2011, 668(1): S10–S15.
[14]	Guidelines for use of nutrition and health claims, CAC/GL 23-1997, Food and Agriculture Organization of the United Nations/ World Health Organization, Adopted in 1997. Revised in 2004. Amended in 2012: 2.
[15]	Studdert VP et al.; Saunders Comprehensive Veterinary Dictionary (4th Ed). Elsevier Health Sciences UK, 2011: 79.
[16]	Biesalski HK et al.; Bioactive compounds: Definition and assessment of activity. Nutrition, 2009, 25(11-12): 1202-1205.
[17]	Solomon HK and William WW; Bioactive Food Components, Encyclopedia of Food & Culture (2nd Ed). Acceptance to Food Politics, B Letter, Charles Scribner's Sons, 2003, 1: 201.
[18]	NahlerG; Dictionary of Pharmaceutical Medicine (3rd Ed), B letter, Springer-Verlag Wien, 2013: 19-28.
[19]	New data on bioactive compounds with putative health benefit (website): http://www.eurofir.net/publications/bioactive_compounds2011.
[20]	Kris-Etherton PM and al.;Bioactive compounds in foods: their role in the prevention of cardiovascular disease and cancer. American Journal of Medicine. 2002, 113(Suppl 9B): 71S-88S.
[21]	Schrezenmeir J et al.; Foreword. British Journal of Nutrition, 2000, 84(S1): 1.
[22]	Gry J et al.;EuroFIR-BASIS - a combined composition and biological activity database for bioactive compounds in plant-based foods. Trends in Food Science & Technology, 2007, 18(8): 434-444.
[23]	Anonymous; Waste: A source of bioactive compounds. Biotechnology Journal, 2008, 3(7) : 1.
[24]	NCI Dictionary of Cancer Terms, National Cancer Institute, Letter B, (website): http://www.cancer.gov/dictionary?cdrid=7032782013.
[25]	Dudareva N and PicherskyE; Biochemical and molecular genetic aspects of floral scent. Plant Physiology, 2000, 122(3): 627–633.
[26]	KarlovskyP; Secondary Metabolites in Soil Ecology, Part II Bacterial Metabolites, Springer, 2008: 93-127.
[27]	ReichenbachH;Myxobacteria, producers of novel bioactive substances. Journal of industrial microbiology & biotechnology, 2001, 27(3) : 149-156.
[28]	Xie Y and al.; Bioactive natural products from Lysobacter. Natural product reports, 2012, 29(11): 1277.
[29]	Rojas JL and al.; Bacterial diversity from benthic mats of Antarctic lakes as a source of new bioactive metabolites. Marine Genomics, 2009, 2(1): 33-41.
[30]	Jaiganesh R and Sampath-Kumar NS; Marine bacterial sources of bioactive compounds. Advances in food and nutrition research, 2012, 65: 389.
[31]	Zhou LL et al.; Effects on animal models of depression of bioactive compounds from entomogenous fungi, a novel antioxidant. Chinese Journal of Integrative Medicine, 2004, 10(3): 221-225.
[32]	Debbab A et al.; Bioactive secondary metabolites from endophytes and associated marine derived fungi. Fungal Diversity, 2011, 49(1): 1–12.
[33]	Peter CKC; Antitumor and Immunomodulatory Activities of Mushroom Polysaccharides: Mushrooms as Functional Foods. 2009: 147–198.
[34]	Liu JK; Bioactive Secondary Metabolites from Higher Fungi in China. PlantaMedica, 2010, 76(5): S17.
[35]	Suarez-Jimenez and al.;Bioactive peptides and depsipeptides with anticancer potential: sources from marine animals. Marine drugs, 2012, 10(5): 963–986.
[36]	Clare DA and SwaisgoodHE;Bioactive milk peptides: a prospectus. Journal of dairy science, 2000, 83(6): 1187.
[37]	Keizo A and MotokoO; Bioactive Compounds in Meat (Chapter 11). Meat Biotechnology, Springer, 2008: 231–249.
[38]	Rainer H et al.; Bioactive Egg Compounds. Springer-Verlag Berlin Heidelberg, 2007: 309p.
[39]	Anne P and Hannu K; Bioactive Peptides and Proteins. Advances in food and nutrition research, 2003, 47: 175- 276.
[40]	John JB and al.; Nature's bounty–drug discovery from the sea. Expert Opinion on Drug Discovery, 2007, 2(11): 1505-22.
[41]	Alphonse K; Secondary metabolites from marine microorganisms, Anais da Academia Brasileira de Ciências, 2002, 74(1): 151-170.
[42]	Maria H; Marine bioactive compounds: sources, characterization, and applications. Springer, 2012: 238p.
[43]	Bhatnagar I and Kim SK; Immense essence of excellence: marine microbial bioactive compounds.Marine drugs, 2010, 8(10): 2673-2701.
[44]	Elga Š and al.; Sea Buckthorn Vegetative Parts – A Good Source of Bioactive Compounds, Proceedings of the Latvian Academy of Sciences. Section B. Natural, Exact, and Applied Sciences, 2013, 2(67): 101-108.
[45]	Debbab A et al.; Bioactive Compounds from Marine Bacteria and Fungi. MicrobialBiotechnology, 2010, 3(5): 544–563.
[46]	CorradoT; Bioactive compounds from natural sources: isolation, characterization and biological properties.London; New York: Taylor & Francis, 2001: 693p.
[47]	CorradoT; Bioactive compounds from natural sources: natural products as lead compounds in drug discovery, Boca Raton: CRC Press (2nd Ed), 2012: 622p.
[48]	BeritSP;Highlights through the history of plant medicine. In: Bioactive compounds in plants – benefits and risks for man and animals. Oslo: The Norwegian Academy of Science and Letters, 2010: 23.
[49]	Arseniyadis S and CossyJ; Modern Tools for the Synthesis of Complex Bioactive Molecules (1st Ed), John Wiley & Sons, 2012: 581p.
[50]	JelenP; Book Review: Bioactive Components in Milk and Dairy Products. International Dairy Journal, 2010, 20(8): 560.
[51]	Goldberg G; Plants: Diet and Health. BNF (British Nutrition Foundation). Wiley & Sons (London), 2003: 2-4.
[52]	Biesalski HK et al.; Bioactive compounds: Safety and efficacy. Nutrition, 2009, 25(11-12): 1206-1211.
[53]	Bhatnagar A et al.; A review on recent advances in Coumarin derivatives with their multidisciplinary actions. Der Pharmacia Lettre, 2010, 2(4): 297-306.
[54]	Mehdi K et al.; Coumarin-Based Bioactive Compounds: Facile Synthesis and Biological Evaluation of Coumarin-Fused 1,4-Thiazepines. Chemical Biology & Drug Design, 2011, 78: 580–586.
[55]	Sadia R et al.; Synthesis and in-vitro antimicrobial screening of 3-cinnamoyl coumarin and 3-[3-(1H-indol-2-yl)-3-aryl-propanoyl]-2H-chromen-2-ones. Iranian Journal of Catalysis, 2013, 3(3): 171-176.
[56]	Borges F et al.; Simple Coumarins and Analogues in Medicinal Chemistry: Occurrence, Synthesis and Biological Activity. Current Medicinal Chemistry, 2005, 12(8): 887-916.
[57]	Kinza A et al.; Synthesis and applications of coumarin. Pakistan Journal of Pharmaceutical Sciences. 2010, 23(4): 449-454.
[58]	Nie J et al.; Simultaneous determination of 6-methylcoumarin and 7-methoxycoumarin in cosmetics using three-dimensional excitation–emission matrix fluorescence coupled with second-order calibration methods. Talanta, 2008, 75:1260–1268.
[59]	Konstantina CF et al.; Natural and Synthetic Coumarin Derivatives with Anti-Inflammatory/Antioxidant Activities. Current Pharmaceutical Design, 2004, 10(30): 3813-3833.
[60]	Liu RH; Health-promoting components of fruits and vegetables in the diet. Advances in Nutrition, 2013, 4(3): 384S-392S.
[61]	Walzem RL et al.; Whey components: millennia of evolution create functionalities for mammalian nutrition: what we know and what we may be overlooking. Critical Reviews in Food Science and Nutrition, 2002, 42: 353–375.
[62]	Niels PM et al.; Bioactive peptides and proteins from foods: indication for health effects, European Journal of Nutrition, 2008, 47:171–182.
[63]	Hernández-Ledesma B et al.; β-Lactoglobulin as source of bioactive peptides. Amino Acids, 2008, 35(2): 257-265.
[64]	Rocio CV et al.; Minor components of pulses and their potential impact on human health. Food Research International, 2010, 43(2): 461-482.
[65]	Spatafora C and TringaliC; Valorization of Vegetable Waste: Identification of Bioactive Compounds and Their Chemo-Enzymatic Optimization. The Open Agriculture Journal, 2012, 6: 9-16.
[66]	Barbosa-Pereira L et al. ; Fractionation and Purification of Bioactive Compounds Obtained from a Brewery Waste Stream. BioMed Research International, 2013: 1-11.
[67]	Gui-Fang D, Potential of Fruit Wastes as Natural Resources of Bioactive Compounds. International Journal of Molecular Sciences, 2012; 13(7): 8308–8323.

Cite This Article

Plain Text BibTeX RIS

APA Style

Abdelkarim GUAADAOUI, Soumaya BENAICHA, Naima ELMAJDOUB, Mohammed BELLAOUI, Abdellah HAMAL. (2014). What is a Bioactive Compound? A Combined Definition for a Preliminary Consensus. International Journal of Nutrition and Food Sciences, 3(3), 174-179. https://doi.org/10.11648/j.ijnfs.20140303.16

Copy | Download

ACS Style

Abdelkarim GUAADAOUI; Soumaya BENAICHA; Naima ELMAJDOUB; Mohammed BELLAOUI; Abdellah HAMAL. What is a Bioactive Compound? A Combined Definition for a Preliminary Consensus. Int. J. Nutr. Food Sci. 2014, 3(3), 174-179. doi: 10.11648/j.ijnfs.20140303.16

Copy | Download

AMA Style

Abdelkarim GUAADAOUI, Soumaya BENAICHA, Naima ELMAJDOUB, Mohammed BELLAOUI, Abdellah HAMAL. What is a Bioactive Compound? A Combined Definition for a Preliminary Consensus. Int J Nutr Food Sci. 2014;3(3):174-179. doi: 10.11648/j.ijnfs.20140303.16

Copy | Download

@article{10.11648/j.ijnfs.20140303.16,
  author = {Abdelkarim GUAADAOUI and Soumaya BENAICHA and Naima ELMAJDOUB and Mohammed BELLAOUI and Abdellah HAMAL},
  title = {What is a Bioactive Compound? A Combined Definition for a Preliminary Consensus},
  journal = {International Journal of Nutrition and Food Sciences},
  volume = {3},
  number = {3},
  pages = {174-179},
  doi = {10.11648/j.ijnfs.20140303.16},
  url = {https://doi.org/10.11648/j.ijnfs.20140303.16},
  eprint = {https://article.sciencepublishinggroup.com/pdf/10.11648.j.ijnfs.20140303.16},
  abstract = {The definition of "bioactive compound" knowdynamism, because the scientific research on the bioactivity potential is booming nowadays. And since there is no unifying definition, attempts to find a consensus and some common elements of the concept associated with the term "bioactive" did not stop, even if vague definitions and repeated use of the operative word "bioactive" almost integrated the term in a category of magic words! This paper tried to find a combined definition which can be a platform to develop the "bioactive" concept, and reach a solid consensus on the term "bioactive compound". We use, for the first time, the term of "biocompounactive" tomore simplify the use of bioactive compound in relation with their physicochemical and biological properties.},
 year = {2014}
}

Copy | Download

TY  - JOUR
T1  - What is a Bioactive Compound? A Combined Definition for a Preliminary Consensus
AU  - Abdelkarim GUAADAOUI
AU  - Soumaya BENAICHA
AU  - Naima ELMAJDOUB
AU  - Mohammed BELLAOUI
AU  - Abdellah HAMAL
Y1  - 2014/05/20
PY  - 2014
N1  - https://doi.org/10.11648/j.ijnfs.20140303.16
DO  - 10.11648/j.ijnfs.20140303.16
T2  - International Journal of Nutrition and Food Sciences
JF  - International Journal of Nutrition and Food Sciences
JO  - International Journal of Nutrition and Food Sciences
SP  - 174
EP  - 179
PB  - Science Publishing Group
SN  - 2327-2716
UR  - https://doi.org/10.11648/j.ijnfs.20140303.16
AB  - The definition of "bioactive compound" knowdynamism, because the scientific research on the bioactivity potential is booming nowadays. And since there is no unifying definition, attempts to find a consensus and some common elements of the concept associated with the term "bioactive" did not stop, even if vague definitions and repeated use of the operative word "bioactive" almost integrated the term in a category of magic words! This paper tried to find a combined definition which can be a platform to develop the "bioactive" concept, and reach a solid consensus on the term "bioactive compound". We use, for the first time, the term of "biocompounactive" tomore simplify the use of bioactive compound in relation with their physicochemical and biological properties.
VL  - 3
IS  - 3
ER  -

Copy | Download

Author Information

Abdelkarim GUAADAOUI

Département de Biologie, Laboratoire de Génétique & Biotechnologie (LGB), Faculté des Sciences – Oujda (FSO), Université Mohammed Premier – Oujda. BP 60000 – Morocco
Soumaya BENAICHA

Département de Biologie, Laboratoire de Génétique & Biotechnologie (LGB), Faculté des Sciences – Oujda (FSO), Université Mohammed Premier – Oujda. BP 60000 – Morocco
Naima ELMAJDOUB

Département de Biologie, Laboratoire de Génétique & Biotechnologie (LGB), Faculté des Sciences – Oujda (FSO), Université Mohammed Premier – Oujda. BP 60000 – Morocco
Mohammed BELLAOUI

Faculté de Médecine et de Pharmacie – Oujda, Université Mohammed Premier – Oujda. BP 60000 – Morocco
Abdellah HAMAL

Département de Biologie, Laboratoire de Génétique & Biotechnologie (LGB), Faculté des Sciences – Oujda (FSO), Université Mohammed Premier – Oujda. BP 60000 – Morocco

Download PDF

Sections

Plain Text BibTeX RIS

APA Style

Abdelkarim GUAADAOUI, Soumaya BENAICHA, Naima ELMAJDOUB, Mohammed BELLAOUI, Abdellah HAMAL. (2014). What is a Bioactive Compound? A Combined Definition for a Preliminary Consensus. International Journal of Nutrition and Food Sciences, 3(3), 174-179. https://doi.org/10.11648/j.ijnfs.20140303.16

Copy | Download

ACS Style

Abdelkarim GUAADAOUI; Soumaya BENAICHA; Naima ELMAJDOUB; Mohammed BELLAOUI; Abdellah HAMAL. What is a Bioactive Compound? A Combined Definition for a Preliminary Consensus. Int. J. Nutr. Food Sci. 2014, 3(3), 174-179. doi: 10.11648/j.ijnfs.20140303.16

Copy | Download

AMA Style

Abdelkarim GUAADAOUI, Soumaya BENAICHA, Naima ELMAJDOUB, Mohammed BELLAOUI, Abdellah HAMAL. What is a Bioactive Compound? A Combined Definition for a Preliminary Consensus. Int J Nutr Food Sci. 2014;3(3):174-179. doi: 10.11648/j.ijnfs.20140303.16

Copy | Download

@article{10.11648/j.ijnfs.20140303.16,
  author = {Abdelkarim GUAADAOUI and Soumaya BENAICHA and Naima ELMAJDOUB and Mohammed BELLAOUI and Abdellah HAMAL},
  title = {What is a Bioactive Compound? A Combined Definition for a Preliminary Consensus},
  journal = {International Journal of Nutrition and Food Sciences},
  volume = {3},
  number = {3},
  pages = {174-179},
  doi = {10.11648/j.ijnfs.20140303.16},
  url = {https://doi.org/10.11648/j.ijnfs.20140303.16},
  eprint = {https://article.sciencepublishinggroup.com/pdf/10.11648.j.ijnfs.20140303.16},
  abstract = {The definition of "bioactive compound" knowdynamism, because the scientific research on the bioactivity potential is booming nowadays. And since there is no unifying definition, attempts to find a consensus and some common elements of the concept associated with the term "bioactive" did not stop, even if vague definitions and repeated use of the operative word "bioactive" almost integrated the term in a category of magic words! This paper tried to find a combined definition which can be a platform to develop the "bioactive" concept, and reach a solid consensus on the term "bioactive compound". We use, for the first time, the term of "biocompounactive" tomore simplify the use of bioactive compound in relation with their physicochemical and biological properties.},
 year = {2014}
}

Copy | Download

TY  - JOUR
T1  - What is a Bioactive Compound? A Combined Definition for a Preliminary Consensus
AU  - Abdelkarim GUAADAOUI
AU  - Soumaya BENAICHA
AU  - Naima ELMAJDOUB
AU  - Mohammed BELLAOUI
AU  - Abdellah HAMAL
Y1  - 2014/05/20
PY  - 2014
N1  - https://doi.org/10.11648/j.ijnfs.20140303.16
DO  - 10.11648/j.ijnfs.20140303.16
T2  - International Journal of Nutrition and Food Sciences
JF  - International Journal of Nutrition and Food Sciences
JO  - International Journal of Nutrition and Food Sciences
SP  - 174
EP  - 179
PB  - Science Publishing Group
SN  - 2327-2716
UR  - https://doi.org/10.11648/j.ijnfs.20140303.16
AB  - The definition of "bioactive compound" knowdynamism, because the scientific research on the bioactivity potential is booming nowadays. And since there is no unifying definition, attempts to find a consensus and some common elements of the concept associated with the term "bioactive" did not stop, even if vague definitions and repeated use of the operative word "bioactive" almost integrated the term in a category of magic words! This paper tried to find a combined definition which can be a platform to develop the "bioactive" concept, and reach a solid consensus on the term "bioactive compound". We use, for the first time, the term of "biocompounactive" tomore simplify the use of bioactive compound in relation with their physicochemical and biological properties.
VL  - 3
IS  - 3
ER  -

Copy | Download