International Journal of Nutrition and Food Sciences

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Rhizome Extract of White Ginger (Zingiber officinale Roxb) Maintains Testicular Function of Aging Mice

Received: 27 March 2016    Accepted: 05 April 2016    Published: 26 April 2016
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Abstract

Ginger is recognized as antioxidants and chemoprotective. Therefore the rhizome extract of this plant could allegedly reverse aging process. The study is intended to investigate the possible effects of rhizome extract of white ginger (Zingiber officinale Roxb.) on the testicular function of aging male mice (Mus musculus Linn.). Male albino mice aged 12-14 months, grouped into three consisted of 12 mice, were given extract orally as follows: 0 mg/kg (as a control), 50mg/kg and 100 mg/kg daily for 70 days. The testicular function parameters assessed were: the number of spermatogenic cells, the number and quality of sperm. Compared to control group, male mice treated with ginger extract showed significant high quality of sperm count, viability, motility and morphology (P<0.001). Histological parameters of the testis: pre-leptotene as well as pachytene spermatocytes and spermatids cells also significantly higher in the treated group (P <0.01) than that of control. In conclusion, rhizome extract of ginger effectively maintain function of reproductive system of male mice in aging process and, thus, ginger is potentially as the fertility and anti-aging herbs.

DOI 10.11648/j.ijnfs.20160503.14
Published in International Journal of Nutrition and Food Sciences (Volume 5, Issue 3, May 2016)
Page(s) 175-178
Creative Commons

This is an Open Access article, distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution and reproduction in any medium or format, provided the original work is properly cited.

Copyright

Copyright © The Author(s), 2024. Published by Science Publishing Group

Keywords

Ginger, Testicular Function, Anti-aging, Antioxidants

References
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[16] Chandrashekar V., Dawson C. R., Martin E. R., Rocha J. S., Bartke A. and Kopchick J. J. (2007). Age-Related Alterations in Pituitary and Testicular Functions in Long-Lived Growth Hormone Receptor Gene-Disrupted Mice. Endocrinology, 148(12): 6019–6025.
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Author Information
  • Department of Biology, Faculty of Mathematics and Natural Sciences University of Lampung, Bandar Lampung, Indonesia

  • Department of Biology, Faculty of Mathematics and Natural Sciences University of Lampung, Bandar Lampung, Indonesia

  • Department of Biology, Faculty of Mathematics and Natural Sciences University of Lampung, Bandar Lampung, Indonesia

  • Department of Anatomical Pathology, Faculty of Medicine, University of Lampung, Bandar Lampung, Indonesia

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    Sutyarso, Hendri Busman, Mohammad Kanedi, Muhartono. (2016). Rhizome Extract of White Ginger (Zingiber officinale Roxb) Maintains Testicular Function of Aging Mice. International Journal of Nutrition and Food Sciences, 5(3), 175-178. https://doi.org/10.11648/j.ijnfs.20160503.14

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    ACS Style

    Sutyarso; Hendri Busman; Mohammad Kanedi; Muhartono. Rhizome Extract of White Ginger (Zingiber officinale Roxb) Maintains Testicular Function of Aging Mice. Int. J. Nutr. Food Sci. 2016, 5(3), 175-178. doi: 10.11648/j.ijnfs.20160503.14

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    AMA Style

    Sutyarso, Hendri Busman, Mohammad Kanedi, Muhartono. Rhizome Extract of White Ginger (Zingiber officinale Roxb) Maintains Testicular Function of Aging Mice. Int J Nutr Food Sci. 2016;5(3):175-178. doi: 10.11648/j.ijnfs.20160503.14

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  • @article{10.11648/j.ijnfs.20160503.14,
      author = {Sutyarso and Hendri Busman and Mohammad Kanedi and Muhartono},
      title = {Rhizome Extract of White Ginger (Zingiber officinale Roxb) Maintains Testicular Function of Aging Mice},
      journal = {International Journal of Nutrition and Food Sciences},
      volume = {5},
      number = {3},
      pages = {175-178},
      doi = {10.11648/j.ijnfs.20160503.14},
      url = {https://doi.org/10.11648/j.ijnfs.20160503.14},
      eprint = {https://download.sciencepg.com/pdf/10.11648.j.ijnfs.20160503.14},
      abstract = {Ginger is recognized as antioxidants and chemoprotective. Therefore the rhizome extract of this plant could allegedly reverse aging process. The study is intended to investigate the possible effects of rhizome extract of white ginger (Zingiber officinale Roxb.) on the testicular function of aging male mice (Mus musculus Linn.). Male albino mice aged 12-14 months, grouped into three consisted of 12 mice, were given extract orally as follows: 0 mg/kg (as a control), 50mg/kg and 100 mg/kg daily for 70 days. The testicular function parameters assessed were: the number of spermatogenic cells, the number and quality of sperm. Compared to control group, male mice treated with ginger extract showed significant high quality of sperm count, viability, motility and morphology (P<0.001). Histological parameters of the testis: pre-leptotene as well as pachytene spermatocytes and spermatids cells also significantly higher in the treated group (P <0.01) than that of control. In conclusion, rhizome extract of ginger effectively maintain function of reproductive system of male mice in aging process and, thus, ginger is potentially as the fertility and anti-aging herbs.},
     year = {2016}
    }
    

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  • TY  - JOUR
    T1  - Rhizome Extract of White Ginger (Zingiber officinale Roxb) Maintains Testicular Function of Aging Mice
    AU  - Sutyarso
    AU  - Hendri Busman
    AU  - Mohammad Kanedi
    AU  - Muhartono
    Y1  - 2016/04/26
    PY  - 2016
    N1  - https://doi.org/10.11648/j.ijnfs.20160503.14
    DO  - 10.11648/j.ijnfs.20160503.14
    T2  - International Journal of Nutrition and Food Sciences
    JF  - International Journal of Nutrition and Food Sciences
    JO  - International Journal of Nutrition and Food Sciences
    SP  - 175
    EP  - 178
    PB  - Science Publishing Group
    SN  - 2327-2716
    UR  - https://doi.org/10.11648/j.ijnfs.20160503.14
    AB  - Ginger is recognized as antioxidants and chemoprotective. Therefore the rhizome extract of this plant could allegedly reverse aging process. The study is intended to investigate the possible effects of rhizome extract of white ginger (Zingiber officinale Roxb.) on the testicular function of aging male mice (Mus musculus Linn.). Male albino mice aged 12-14 months, grouped into three consisted of 12 mice, were given extract orally as follows: 0 mg/kg (as a control), 50mg/kg and 100 mg/kg daily for 70 days. The testicular function parameters assessed were: the number of spermatogenic cells, the number and quality of sperm. Compared to control group, male mice treated with ginger extract showed significant high quality of sperm count, viability, motility and morphology (P<0.001). Histological parameters of the testis: pre-leptotene as well as pachytene spermatocytes and spermatids cells also significantly higher in the treated group (P <0.01) than that of control. In conclusion, rhizome extract of ginger effectively maintain function of reproductive system of male mice in aging process and, thus, ginger is potentially as the fertility and anti-aging herbs.
    VL  - 5
    IS  - 3
    ER  - 

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