Screening of Potential Sources of Tannin and Its Therapeutic Application
International Journal of Nutrition and Food Sciences
Volume 4, Issue 2-1, March 2015, Pages: 26-29
Received: Nov. 18, 2014; Accepted: Dec. 4, 2014; Published: Mar. 21, 2015
Views 2840      Downloads 152
Mamta Kumari, Polytechnic in Home Science, Junagadh Agricultural University, Keriya Road, Amreli, Gujarat-365601, India
Shashi Jain, Department of Foods & Nutrition, College of Home Science, MPUAT, Udaipur, Rajasthan-313001, India
Article Tools
Follow on us
Tannins are a unique category of plant phytochemicals especially in terms of their vast potential health-benefiting properties. Researchers have described the capacity of tannins to enhance glucose uptake and inhibit adipogenesis, thus being potential drugs for the treatment of non-insulin dependent diabetes mellitus. Thus, the present research was conducted to find out tannin content of food products. The percentage of tannin in various analyzed sources ranged from 0.0 to 108.53%; highest in kathaa and lowest in ker and mango bark. The percentage of tannins present in the plants, however, varies. Numerous studies have confirmed that the naturally occurring polyphenols are key factor for the beneficial effects of the herbal medicines. Isolation and identification of active constituents from plants, preparation of standardized dose & dosage regimen can play a significant role in improving the hypoglycaemic action.
Tannins, Diabetes, Polyphenols, Antioxidant, Hypoglycemia
To cite this article
Mamta Kumari, Shashi Jain, Screening of Potential Sources of Tannin and Its Therapeutic Application, International Journal of Nutrition and Food Sciences. Special Issue:Functional Foods and Nutraceuticals for Management of Type 2 Diabetes. Vol. 4, No. 2-1, 2015, pp. 26-29. doi: 10.11648/j.ijnfs.s.2015040201.15
Spencer JP, Abd El Mohsen MM, Minihane AM & Mathers JC, Biomarkers of the intake of dietary polyphenols: Strengths, limitations and application in nutrition research, Br J Nutr, 99 (2008)12-22.
Beckman CH, Phenolic-storing cells: keys to programmed cell death and periderm formation in wilt disease resistance and in general defence responses in plants, Physiol Mol Plant Pathol 57 (2000) 101-10.
Manach C, Scalbert A, Morand C, Rémésy C & Jimenez L, Polyphenols: food sources and bioavailability, Am J Clin Nutr 79 (2004) 727-47.
Kashiwada Y, Huang L, Kilkuskie RE, Bodner AJ and Lee KH, Bioorg Med Chem Lett 2 (1992) 235.
Khanbabaee K & Van Ree T, Tannins: Classification and definition, Nat Prod Rep 18 (2001) 641-649.
Bennick A, Interaction of plant polyphenols with salivary proteins, Crit Rev Oral Biol Med 13 (2002) 184-196.
The international Pharmacopoeia, World Health Organization, 3rd ed., v. 5, Geneva, 2003.
AOAC, Official Method, Spectrophotometric Method, 1965.
Beecher GR, Phytonutrients’ role in metabolism: effects on resistance to degenerative processes, Nutr Rev, 9(Part II) (1999) S3-S6.
Hines E, New nutritive substances: beyond the ABCs, Food Quality 6 (1999) 39-43.
Rhodes M & Price KR, Phytochemicals: classification and occurrence, In: Encyclopedia of Human Nutrition, Academic Press/Harcourt Brace & Company Publishers New York, NY, 1999, 1539-1549
Pinent M, Blay M, Blade ML, Salvado MJ, Arola L & Ardevol A, Grape seed derived procyanidins have an antihyperglycemic effect in Streptozotocin induced Diabetic rats and insulinmimetic activity in insulin sensitive cell lines, Endocrinology, 145 (11) (2004) 4985-4990.
Shimizu M, Kobayashi K, Suzuki M, Satsu H & Miyamoto Y, Regulation of intestinal glucose transport by tea catechins, Biofactors, 13 (2000) 61-65.
Terril TH, Rowan AM, Douglas GB & Barry TN, Determination of extractable and bound condensed tannin concentrations in forage plants, protein concentrate meals and cereal grains, J Sci Food Agric 58 (1992) 321-329.
Van Soest PJ, Nutritional ecology of the ruminant, 2nd ed. Cornell Univ Press, Ithaca, NY, USA, 1994, 476
Álvarez Del Pino MC, Frutos P, Hervás G, Gómez A, Giráldez FJ & Mantecón AR, Efecto del contenido de taninos en la degradación ruminal in vitro de varios órganos de especies arbustivas, ITEA, Prod Anim 22 (2001) 355-357.
Rhoades DF, Evolution of plant chemical defense against herbivores. In: Herbivores: their interactions with secondary plant metabolites (Rosenthal G.A. and Janzen D.H., eds.), Academic Press, NY, USA, 1979, 3-54.
Bravo L, Polyphenols: chemistry, dietary sources, metabolism and nutritional significance, Nutrition Reviews, 56 (1998) 317-333.
Schroeter H, Boyd C, Spencer JP, Williams RJ, Cadenas E & Rice-Evans C, MAPK signaling in neurodegeneration: influences of flavonoids and of nitric oxide, Neurobiol Aging 23 (2002) 861-880.
Spencer JP, Rice-Evans C & Williams RJ, Modulation of pro-survival Akt/protein kinase B and ERK1/2 signaling cascades by quercetin and its in vivo metabolites underlie their action on neuronal viability, J Biol Chem, 278 (2003) 34783-34793.
Agullo G, Gamet-Payrastre L, Manenti S, Viala C, Rémésy C, Chap H & Payrastre B, Relationship between flavonoid structure and inhibition of phosphatidylinositol 3-kinase: a comparison with tyrosine kinase and protein kinase C inhibition, Biochem Pharmacol, 53 (1997) 1649-1657.
Vlahos CJ, Matter WF, Hui KY & Brown RF, A specific inhibitor of phosphatidylinositol 3-kinase, 2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one (LY294002), J Biol Chem, 269 (1994) 5241-5248.
Gamet-Payrastre L, Manenti S, Gratacap MP, Tulliez J, Chap H & Payrastre B, Flavonoids and the inhibition of PKC and PI 3-kinase, Gen Pharmacol, 32 (1999) 279-286.
Williams RJ, Spencer JP & Rice-Evans C, Flavonoids: antioxidants or signaling molecules, Free Radic Biol Med, 36 (2004) 838-849.
Heim KE, Tagliaferro AR & Bobilya DJ, Flavonoid antioxidants: chemistry, metabolism and structure-activity relationships, J Nutr Biochem, 13 (2002) 572-584.
Science Publishing Group
1 Rockefeller Plaza,
10th and 11th Floors,
New York, NY 10020
Tel: (001)347-983-5186