The present study was undertaken to evaluate the anti-obesity potential of a phenolic- rich herbal tea beverage produced in northern regions of Cameroon from the leaves of Stathmostelma sp. (Statroltea). The effect of Statroltea (5 mg/Kg/day) on lipid metabolism was assayed in male rats fed on either standard or high-fat diet for 60 days. Rats of both diet fed Statroltea presented significant (P < 0.05) reduced body weight than their controls with a rate of reduction varying from 5 to 15%. The consumption of Statroltea for 60 days significantly lowered abdominal fat index, blood total and LDL cholesterol, triglycerides and hepatic lipids (P < 0.05). Fecal lipids were found to be more excreted in all Statroltea fed rats. This is the first report on the effect of Stathmostelma sp. leaves on lipid metabolism and the study demonstrates that Statroltea, an herbal tea from Stathmostelma sp. leaves has a potential as anti-obesity functional food beverage.
| Published in | Journal of Food and Nutrition Sciences (Volume 2, Issue 4) |
| DOI | 10.11648/j.jfns.20140204.11 |
| Page(s) | 99-104 |
| Creative Commons |
This is an Open Access article, distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution and reproduction in any medium or format, provided the original work is properly cited. |
| Copyright |
Copyright © The Author(s), 2024. Published by Science Publishing Group |
Obesity, Lipid Metabolism, Statroltea, Herbal Tea, Functional Food Beverage
| [1] | G. Kopelman, “Obesity as a medical problem,” Nature, vol. 404, 2000, pp. 635–643. |
| [2] | WHO Global strategy on diet, physical activity and health. World Health Report Geneva (2004). |
| [3] | E. Kishino, T. Ito, K. Fujita and Y. Kiuchi, “A mixture of the Salacia reticulata (Kotala himbutu) aqueous extract and cyclodextrin reduces the accumulation of visceral fat mass in mice and rats with high-fat diet-induced obesity,” Journal of Nutrition, vol. 136, 2006, pp. 433–439. |
| [4] | L.-K. Han, Y. Kimura, M. Kawashima, T. Takaku, T. Taniyama, T. Hayashi, Y.-N. Zheng and H. Okuda, “Anti-obesity effects in rodents of dietary teasaponin, a lipase inhibitor,” International Journal of Obesity, vol. 25, 2001, pp. 1459–1464. |
| [5] | F. Martins, T. M. Noso, V. B. Porto, A. Curiel, A. Gambero, D. H. M. Bastos, M. L. Ri-beiro and P. O. Carvalho, “ Maté Tea Inhibits In Vitro Pancreatic Lipase activity and Has Hypolipidemic Effect on High-fat Diet-induced Obese Mice”, Obesity, vol. 18, 2010, pp. 42–47. |
| [6] | S. I. Koo and S. K. Noh, “Green tea as inhibitor of the intestinal absorption of lipids: potential mechanism for its lipid-lowering effect,” Journal of Nutritional Biochemistry, vol. 18, 2007, pp. 179- 183. |
| [7] | D. R. Feumba, E. G. F. Ngando, J. E. Oben and C. M. F. Mbofung, “A Phenolic-Rich Herbal Tea from Stathmostelma sp. (Statroltea) Inhibits In Vitro Pancreatic Lipase Activity,” Journal of Enzyme Research, vol. 4, 2013, pp. 50-53. |
| [8] | W. T. Friedewald, R. I. Levy and D. S. Fredrickson, “Estimation of the concentration of low-density lipoprotein cholesterol in plasma, without use of the preparative ultracentrifuge,” Clinical Chemistry, vol.18, 1972, pp. 499–502. |
| [9] | J. Folch, M. Lees and G. H. Sloane-Stanley, “A simple method for the isolation and purification of total lipids from animal tissues,” Journal of Biological Chemistry, vol. 226, 1957, pp. 497 - 509. |
| [10] | K. A. Amin and M. A. Nagy, “ Effect of Carnitine and herbal mixture extract on obesity induced by high fat diet in rats,” Diabetology & Metabolic Syndrome, vol. 1, 2009, pp. 1-14. |
| [11] | S. M. Grundy, J. I. Cleeman, S. R. Daniels, K. A. Donato, R. H. Eckel, B. A. Franklin, “Diagnosis and management of the metabolic syndrome: an American Heart Association/National Heart, Lung, and Blood Institute Scientific Statement,” Circulation, vol. 112, 2005, pp. 2735-2752. |
| [12] | M. Sogawa, T. Seura, S. Kohno, K. Hirasaka, Y. Yamaguchi, R. Takagaki, A. Harada, Y. Okumura, S. Yamamoto, K. Kishi and T. Nikawa, “ Awa (Tokushima) lactate-fermented tea as well as green tea enhance the effect of diet restriction on obesity in rats,” The Journal of Medical Investigation, vol. 56, 2009, pp. 42-48. |
| [13] | Hala, E. M. El-Kewawy, Farida, A. Al-Firdous and R. M. Nagib, “Beneficial effects of some beverage consumption and Orlistat drug on Diet Induced Obesity in Experimental Rate,” Life Science Journal, vol. 8, 2011, pp. 667-675. |
| [14] | Y. -H. Kao, R. A., Hiipakka and S. Liao, “Modulation of obesity by a green tea catechin,” American Journal of Clinical Nutrition, vol. 72, 2000, pp. 1232 –1234. |
| [15] | Y. -H. Kao, R. A., Hiipakka and S. Liao, “Modulation of Endocrine Systems and Food Intake by Green Tea Epigallocatechin Gallate,” Endocrinology, vol. 141, 2000, pp. 980–987. |
| [16] | J. Bajerska, M. Wozniewicz, J. Jeszka, S. Drzymala-Czyz and J. Walkowiak, “Green tea aqueous extract reduces visceral fat and decreases protein availability in rats fed with a high-fat diet,” Nutrition Re-search, vol. 31, 2011, pp. 157-164. |
| [17] | Y. Nakamura, A. Kaihara, K. Yoshii, Y. Tsumura, S. Ishimitsu and Y. Tonogai, “Effects of the Oral Administration of Green Tea Polyphenol and Tannic Acid on Serum and Hepatic Lipid Contents and Fecal Steroid Excretion in Rats,” Journal of Health Science, vol. 47, 2001, pp. 107-111. |
| [18] | Ikeda, R. Ha-mamoto, K. Uzu, K. Imaizumi, K. Nagao, T. Yanagita, Y. Suzuki, M. Kobayashi and T. Kakuda, “Dietary Gallate Esters of Tea Catechins Reduce Deposition of Visceral Fat, Hepatic Triacylglycerol and Activities of Hepatic Enzymes Related to Fatty Acid Synthesis in Rats,” Bioscience Biotechnology & Biochemistry, vol. 69, 2005, pp. 1049–1053. |
| [19] | Toki-mitsu, “Effects of tea catechins on lipid metabolism and body fat accumulation,” Biofac, vol. 22, 2004, pp. 141-143. |
| [20] | Y. Ito, T. Ichikawa, Y. Morohoshi, T. Nakamura, Y. Saegusa and K. Ishihara, “Effect of tea catechins on body fat accumulation in rats fed a normal diet,” Biomedical Research, vol. 29, 2008, pp. 27-32. |
| [21] | M. N. Woo, S. H. Bok and M. S. Choi, “Hypolipidemic and body fat –lowering effects of Fatclean in rats fed a high-fat diet,” Food and Chemical Toxicology, vol. 47, 2009, pp. 2076-2082. |
| [22] | Z. Zdunczyk, S. Frejnagel, M. Wroblewska, J. Juskiewicz, J. Oszmianski and I. Estrella, “Biological activity of polyphenol extracts from different plant sources,” Food Research International, vol. 35, 2002, pp. 183-186. |
| [23] | Lipid Research Clinics Program, “The lipid research clinics coronary primary prevention trial results: 11. The relationship of reduction in incidence of coronary heart disease to cholesterol lowering,” Journal of American Medical Association, vol. 251, 1984, pp. 365–374. |
| [24] | G. Ramadan, N. M. El-Beih and E. A. Abd El-Ghffar, “Modulatory effects of black v. green tea aqueous extract on hyperglycaemia, hyperlipidaemia and liver dysfunction in diabetic and obese rat models,” British Journal of Nutrition, vol. 102, 2009, pp. 1611–1619. |
| [25] | P. W. F. Wilson, “High density lipoprotein, low density lipoprotein and coronary heart disease,” American Journal of Cardiology, vol. 66, 1990, pp.7A–10A. |
| [26] | R. Devi and D. K. Sharma, “Hypolipidemic effect of different extracts of Clerodendron colebrookianum Walp in normal and high-fat diet fed rats,” Journal of Ethnopharmacology, vol. 90, 2004, pp. 63–68. |
| [27] | L. De la Garza, F. I. Milagro, N. Boque, J. Campion and J. A. Martinez, “Natural inhibitors of Pancreatic Lipase as new players in obesity treatment,” Planta Medica, vol. 77, 2011, pp. 773 -785. |
| [28] | S. Uchiyama, Y. Taniguchi, B. A. Saka, A. Yoshida and H. Yajima, “Prevention of di-et-induced obesity by dietary black tea polyphenols extract in vitro and in vivo,” Nutrition, vol. 27, 2011, pp. 287–292. |
| [29] | T. Murase, A. Nagasawa, J. Suzuki, T. Hase and I. Tokimitsu, “Beneficial effects of tea catechins on diet-induced obesity: stimulation of lipid catabolism in the liver,” International Journal of Obesity, vol. 26, 2002, pp. 1459–1464. |
| [30] | S. De Vos and R. De Schrijver, “Lipid metabolism, intestinal fermentation and mineral absorption in rats consuming black tea”, Nutrition Research, vol. 23, 2003, pp. 527 –537. |
| [31] | S. Nishikawa, K. Doi, H. Nakayama and K. Uetsuka, “The Effect of Fasting on Hepatic Lipid Accumulation and Transcriptional Regulation of Lipid Metabolism Differs between C57BL/6J and BALB/cA Mice Fed a High-fat Diet”, Toxicologic Pathology, vol. 36, 2008, pp. 850-857. |
| [32] | K. Kobayashi-Hattori, A. Mogi, Y. Matsumoto and T. Takita, “Effect of caffeine on the body fat and lipid metabolism of rats fed on a high-fat diet”, Bioscience Biotechnology & Biochemistry, vol. 69, 2005, pp. 2219-223. |
| [33] | T.-F. Hsu, A. Kusumoto, K. Abe, K. Hosoda, Y. Kiso, M.-F. Wang and S. Yamamoto, “Polyphe-nol-enriched oolong tea increases fecal lipid excretion,” European Journal of Clinical Nutrition, vol. 60, 2006, pp. 1330-1336. |
APA Style
Feumba Dibanda Romelle, Oben Julius Eyong, Mbofung Carl Moses. (2014). Effect of Statroltea on Lipid Metabolism in Rats Fed on High-Fat Diet. Journal of Food and Nutrition Sciences, 2(4), 99-104. https://doi.org/10.11648/j.jfns.20140204.11
ACS Style
Feumba Dibanda Romelle; Oben Julius Eyong; Mbofung Carl Moses. Effect of Statroltea on Lipid Metabolism in Rats Fed on High-Fat Diet. J. Food Nutr. Sci. 2014, 2(4), 99-104. doi: 10.11648/j.jfns.20140204.11
AMA Style
Feumba Dibanda Romelle, Oben Julius Eyong, Mbofung Carl Moses. Effect of Statroltea on Lipid Metabolism in Rats Fed on High-Fat Diet. J Food Nutr Sci. 2014;2(4):99-104. doi: 10.11648/j.jfns.20140204.11
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Download@article{10.11648/j.jfns.20140204.11,
author = {Feumba Dibanda Romelle and Oben Julius Eyong and Mbofung Carl Moses},
title = {Effect of Statroltea on Lipid Metabolism in Rats Fed on High-Fat Diet},
journal = {Journal of Food and Nutrition Sciences},
volume = {2},
number = {4},
pages = {99-104},
doi = {10.11648/j.jfns.20140204.11},
url = {https://doi.org/10.11648/j.jfns.20140204.11},
eprint = {https://article.sciencepublishinggroup.com/pdf/10.11648.j.jfns.20140204.11},
abstract = {The present study was undertaken to evaluate the anti-obesity potential of a phenolic- rich herbal tea beverage produced in northern regions of Cameroon from the leaves of Stathmostelma sp. (Statroltea). The effect of Statroltea (5 mg/Kg/day) on lipid metabolism was assayed in male rats fed on either standard or high-fat diet for 60 days. Rats of both diet fed Statroltea presented significant (P < 0.05) reduced body weight than their controls with a rate of reduction varying from 5 to 15%. The consumption of Statroltea for 60 days significantly lowered abdominal fat index, blood total and LDL cholesterol, triglycerides and hepatic lipids (P < 0.05). Fecal lipids were found to be more excreted in all Statroltea fed rats. This is the first report on the effect of Stathmostelma sp. leaves on lipid metabolism and the study demonstrates that Statroltea, an herbal tea from Stathmostelma sp. leaves has a potential as anti-obesity functional food beverage.},
year = {2014}
}
TY - JOUR T1 - Effect of Statroltea on Lipid Metabolism in Rats Fed on High-Fat Diet AU - Feumba Dibanda Romelle AU - Oben Julius Eyong AU - Mbofung Carl Moses Y1 - 2014/06/20 PY - 2014 N1 - https://doi.org/10.11648/j.jfns.20140204.11 DO - 10.11648/j.jfns.20140204.11 T2 - Journal of Food and Nutrition Sciences JF - Journal of Food and Nutrition Sciences JO - Journal of Food and Nutrition Sciences SP - 99 EP - 104 PB - Science Publishing Group SN - 2330-7293 UR - https://doi.org/10.11648/j.jfns.20140204.11 AB - The present study was undertaken to evaluate the anti-obesity potential of a phenolic- rich herbal tea beverage produced in northern regions of Cameroon from the leaves of Stathmostelma sp. (Statroltea). The effect of Statroltea (5 mg/Kg/day) on lipid metabolism was assayed in male rats fed on either standard or high-fat diet for 60 days. Rats of both diet fed Statroltea presented significant (P < 0.05) reduced body weight than their controls with a rate of reduction varying from 5 to 15%. The consumption of Statroltea for 60 days significantly lowered abdominal fat index, blood total and LDL cholesterol, triglycerides and hepatic lipids (P < 0.05). Fecal lipids were found to be more excreted in all Statroltea fed rats. This is the first report on the effect of Stathmostelma sp. leaves on lipid metabolism and the study demonstrates that Statroltea, an herbal tea from Stathmostelma sp. leaves has a potential as anti-obesity functional food beverage. VL - 2 IS - 4 ER -
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