Hypervitaminia B12: An Unknown Endocrine Marker
Journal of Food and Nutrition Sciences
Volume 3, Issue 2, March 2015, Pages: 32-34
Received: Aug. 1, 2014;
Accepted: Feb. 10, 2015;
Published: Feb. 16, 2015
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Zulfiqar A. A., Department of Internal Medicine and Geriatrics, University Hospital of Reims, Reims, France
Sebaux A., Department of Internal Medicine and Geriatrics, University Hospital of Reims, Reims, France
Andrès E., Department of Internal Medicine, University of Strasbourg, Strasbourg, France
Novella J. L., Department of Internal Medicine and Geriatrics, University Hospital of Reims, Reims, France
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Measurement of serum cobalamin (vitamin B12) is routinely used in Endocrinology/Metabolism in order to diagnose or rule out a suspected Cobalamin deficiency. Hypervitaminemia B12 or high serum level of cobalamin B12 is a clinical underestimated abnormality. A high fraction of patients have high cobalamin levels and no consensus exists regarding the clinical implications for this endocrine marker, which can be involved in serious medical situations like solid neoplasms, hepatopathy, hemopathy, renal failure, and also in case of functional deficiency. We describe four clinical cases illustrating this problem, and possible links between Hypervitaminia B12 and malignant diseases, potentially engaging the prognosis.
Hypervitaminia B12, Solid Neoplasms, Hemopathy, Renal Failure, Hepatic Disorders
To cite this article
Zulfiqar A. A.,
Novella J. L.,
Hypervitaminia B12: An Unknown Endocrine Marker, Journal of Food and Nutrition Sciences.
Vol. 3, No. 2,
2015, pp. 32-34.
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