The Ingestion of High-Fructose Syrup-Containing Cola with a Hamburger Delays Postprandial Lipid Metabolism in Young Healthy Japanese Women
Journal of Food and Nutrition Sciences
Volume 3, Issue 4, July 2015, Pages: 139-146
Received: Apr. 30, 2015; Accepted: May 26, 2015; Published: Jun. 9, 2015
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Authors
Hiromi Saito, Division of Nutrition & Health, School & Graduate School of Life Studies, Sugiyama Jogakuen University, Nagoya, Japan; Department of Food Science and Nutrition, Nara Women’s University, Nara, Japan
Maiko Kato, Division of Nutrition & Health, School & Graduate School of Life Studies, Sugiyama Jogakuen University, Nagoya, Japan
Akihiro Yoshida, Department of Clinical Laboratory, Nakatsugawa Municipal General Hospital, Nakatsugawa, Japan
Michitaka Naito, Division of Nutrition & Health, School & Graduate School of Life Studies, Sugiyama Jogakuen University, Nagoya, Japan
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Abstract
Aim: To investigate the acute effects of the ingestion of high-fructose syrup (HFS)-containing cola in combination with a hamburger on postprandial lipid metabolism. Methods: Twelve young healthy women with apolipoprotein E phenotype 3/3 were enrolled in the study. Each subject underwent 3 test trials in a randomized crossover design. The trials were as follows: C trial, cola (350 mL, containing HFS); H trial, 1 hamburger; CH trial, cola + hamburger. Venous blood samples were collected at fasting levels and at 0.5, 1, 2, 4, and 6 h after ingestion. Results: The serum concentrations of triglyceride (TG), remnant-like particle (RLP)-TG, and apolipoprotein B-48 (apoB48) peaked at 2 h in the H trial and at 4 h in the CH trial. Compared with each fasting level, the serum TG concentration in the H trial was significantly increased at 1, 2, and 4 h, and it returned to the fasting level at 6 h. However, compared with each fasting level, the TG concentration in the CH trial was significantly increased at 4 and 6 h, and it did not return to the fasting level at 6 h. The serum apoB48 concentration peaked at 2 h in the H trial and at 4 h in the CH trial. The apoB48 concentration at 4 and 6 h and the incremental area under the curve for apoB48 in the CH trial tended to be higher than those in the H trial. Conclusion: The ingestion of cola in combination with a hamburger delayed and extended postprandial lipidemia in comparison with the ingestion of a hamburger only, suggesting that fructose contained in the cola exacerbates postprandial lipid metabolism.
Keywords
Fructose, Apolipoprotein B-48, Postprandial Lipidemia, Triglyceride-Rich Lipoprotein, Fast Food
To cite this article
Hiromi Saito, Maiko Kato, Akihiro Yoshida, Michitaka Naito, The Ingestion of High-Fructose Syrup-Containing Cola with a Hamburger Delays Postprandial Lipid Metabolism in Young Healthy Japanese Women, Journal of Food and Nutrition Sciences. Vol. 3, No. 4, 2015, pp. 139-146. doi: 10.11648/j.jfns.20150304.11
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