Effects of Oral Coenzyme Q10 on Preventing the Accumulation of Lactic Acid Developing during the Exercise Performances of Endurance Skiing Athletes
American Journal of Sports Science
Volume 2, Issue 3, May 2014, Pages: 65-70
Received: May 27, 2014;
Accepted: Jun. 3, 2014;
Published: Jun. 10, 2014
Views 3690 Downloads 253
Nevzat Demirci, Mersin School of Physical Education and Sports, Mersin University, Mersin, Turkey
Ebru Beytut, Department of Physiology, Faculty of Medicine, University of Erzincan, Erzincan, Turkey
Aim: This study aims to examine the effects of oral coenzyme Q10 (CoQ10) on preventing the accumulation of lactic acid developing during the exercise performances of endurance skiing athletes. Materials and Methods: The study population was composed of 15 volunteering male athletes. The blood samples thus collected were utilized for the measurement of athletes’ CoQ10, lactate, lactate dehydrogenase (LDH), creatine phosphokinase (CPK), heart rate and blood pressure. Results: Significant decreases were identified in the systolic and diastolic blood pressures, pulses and plasma lactate levels of the athletes in the trial group when their pre- and post-exercise results were compared (p<0,01; p<0,001) while an increase of p<0,01 was observed in their plasma CoQ10 levels. However, plasma LDH and CPK levels of the trial group athletes using 100 and 200 mg CoQ10 were observed to increase less when compared to the results of the control group athletes in seven days (p<0,001; p<0,01). Conclusion: regular and gradual exercise is considered to enhance physical performance depending on the usage of CoQ10 while it decreases the accumulation of La and thus delays fatigue.
Effects of Oral Coenzyme Q10 on Preventing the Accumulation of Lactic Acid Developing during the Exercise Performances of Endurance Skiing Athletes, American Journal of Sports Science.
Vol. 2, No. 3,
2014, pp. 65-70.
E.L. Fox, R.W. Bowers and M.C. Foos. Physical Education and Physiological Basics of Sports. Translated By: Cerit, M. Ed: Yaman, H. Ankara, Bağırgan Yayınevi. 1999.
G. Ersoy. Nutrition for Exercise and Sports Performance, Ankara, Ata offset. 2006.
M. Günay. Exercise Physiology, Ankara, Bağırgan Yayım evi. 1998.
J.A. Schwane, R.T. Buckley, D.P. Dipaolo, M. Atkınson and J.R. Shepherd. Plasma creatine kinase responses of 18- to 30-yr-old afri-can-american men to eccentric exercise. Med. Sci. Sports Exerc 2000; 23 (2): 370-378.
M. Kei, M. Tanaka, S. Nozaki, H. Mizuma, S. Ataka, T. Tahara, T. Sugino, T. Shirai, Y. Kajimoto, H. Ku-ratsune, O. Kajimoto and Y. Watanabe. Antifatigue effects of coenzyme Q10 during physical fati-gue. Nutrition 2008; 24: 293–299.
E.H. Wıtt, A.Z. Rezhıck, C.A. Vıguıe, P. Starke- Reed and L. Packer. Exercise, oxidative damage and effects of antioxidant manipulation. J. Nutr. 1992; 122: 766- 773.
L. Frederick, PhD. Crane. Biochemical functions of coenzyme q10. Journal of the American College Of Nutrition 2001; Vol. 20, No. 6, 591–598.
F. Mosca, D. Fatto-rini, S. Bompadre and GP. Littarru. Assay of coenzyme q10 in plasmaby a single dilution step. Anal. Biochem 2002; 305: 49-54.
K. Tamer. Measuring and Evaluating Physical Physi-ological Performance in Sports Ankara, Bağırgan Yayın Evi. 2000.
SAS Puphlishing, SAS/STAT 9.2 User’s Guide The GLM Procedure (Book Excerpt), 2008.
V.L. Billat. Use of blood lactate measure ments for prediction of exercise performance and forcontrol of training. Sports Med 1996; 22: 157-75.
A.S. Gürkan, O. Bozdağ and O. Dündar. Coenzyme Q10, Ankara Journal Of Faculty Of Pharmacy 2005; 34 (2) 129 –154.
F. Rosenfeldt, D. Hilton, S. Pepe and H. Krum. Systematic review of effect of coenzyme Q10 in physical exercise, hypertension and heart failure. Biofactors 2003; 18, 91- 100.
J.M. Hodgson, G.F. Watts, D.A. Playford, V. Burke and K.D. Croft.Coenzyme Q10 improves blood pressure and glycaemic control: a control ledtrial in subjects with type 2 diabetes. European Journal of clinical Nutrition 2002; 56,1137-1142.
A.W. Linnane, G. Kopsidas, C. Zhang, N. Yarovaya, S. Kovalenko, P. Papa-kostopoulos, H. Eastwood, S. Graves and M. Richardson. Cellular redoxactivity of coenzyme Q10: effect of CoQ10 supplementation on human skeletal muscle. Free Radic Res. 2002; 36:445–453.
J.H. Wilmore, P.R. Stanforth, J. Gagnon, A.S. Leon, D.C. Rao, J.S. Skinner and C. Bouchard. Enduranc eexercise training has a minimal on resting heart rate the herltage study. Medicine And Science İn Sport And Exercise 1996; 28 (7): 829-35.
V. Di-giesi, F. Cantini, A. Oradei and G. Bisi. Coenzyme Q10 in essential hypertension. Mol. Aspects. Med 1994; 15, 257-263.
K. Salbaş, R. Karaoguz and A. Sonel. The Effect of coenzyme q10 on hypoxia and reoxijenation insulated rabbit right atrium spontaneous contractile activity and tissue damage. Turkey Clinics Cardiology 1989; 2: 108-113.
T. Ylikoski, J. Piirainen, O. Hanninen and J. Penttinen. Theeffect of coenzyme Q10 on the exercise performance of cross-country skiers. Molec Aspects Med. 1997; 18: 283-290.
D.A. Porter, D.L. Costill, J.J. Zachwieja, K. Krzeminski W.J. Fink, E. Wagner and K. Folkers. Theeffect of oral coenzyme Q10 on the exercise tolerance of middle – aged untrained men. Clinical Neurop harmacology 1995; 27: 4, 187-191.
S. Fujimoto, N. Kurihara, K. Hirata and T. Takeda. Effects of coenzyme Q10 administration on pulmonary function and exercise performance in patients with chronic lung diseases. Clin Investig 1993; 71:S 162 S 166.
S.B. Weston, S. Zhou, Rp. Weatherby and SJ. Robson. Does exegenous coenzyme Q10 affect aerobic capacity in endurance athletes. Int J. Sport Nutr 1997; 7(3):197-206.
A. Bonetti, F. Solito, G. Carmosino, A.M. Bargossi and PL. Fıorella. Effect of ubidecarenone oral treatment on aerobic power in middle-aged trained subject. Journal of Sports
M. Cooke, M. Iosia, T. Buford, B. Shelmadine, G. Hudson, C. Kerksick, C. Rasmussen, M. Greenwood, B. Leutholtz and D. Willoughby. Effects of acuteand 14-day coenzyme Q1 supplementation on exercise performance in both trained and untrained individuals. Int Soc Sports Nutr 2008; March 4. doi: 10.1186/1550-2783-5-8.