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Characterization of Urinary Bladder in Khat Chewing Yemeni Students Using Ultrasonography

Received: 3 February 2014    Accepted:     Published: 10 March 2014
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Abstract

Khat is a natural stimulant from the Catha Edulis plant and is cultivated in the Republic of Yemen and certain areas of East Africa. Khat produces a modest degree of euphoria and slight hypomania. It results in insomnia and appears to improve the users' alertness and concentration. The main objective of this study was to determine ultrasound findings of urinary bladder among Yemeni khat chewers higher education students. Fifty khat chewers volunteers from higher Education levels were selected as cases, and twenty non-khat chewer volunteers at University level serving as control group. All of them were undergone urinary bladder ultrasound scan. This study revealed that the high frequency of students who chewed khat were from Dhamar area. The study showed that there is a linear relationship between the urinary bladder wall thickness and chewing Khat for years and hours and the residual urine volume is greater in students who chewed the Khat than the control group. Correlation is significant at the P=0.000 for chewing Khat for years and hours.

Published in International Journal of Medical Imaging (Volume 2, Issue 2)
DOI 10.11648/j.ijmi.20140202.11
Page(s) 10-13
Creative Commons

This is an Open Access article, distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution and reproduction in any medium or format, provided the original work is properly cited.

Copyright

Copyright © The Author(s), 2024. Published by Science Publishing Group

Keywords

Khat, Ultrasound, Urinary Bladder

References
[1] J. G. Kennedy,. The Flower of Paradise - The Institutionalized Use of the Drug Khat In North Yemen. D. Reidel: Dordrecht(1987)
[2] A. D. Krikorian, Kat and its use: an historical perspective. Journal of Ethno pharmacology (1984). 12, 115-178
[3] P. Kalix, O. Braenden,. Pharmacological aspects of the chewing of khat leaves. Pharmacological Reviews 37, (1985). 149-164.
[4] J. G ,Kennedy, J.Teague, W. Rokaw, E. Cooney,. A medical evaluation of the use of khat in North Yemen. Society Science and Medicine (1983). 17, 783-793
[5] H Halbach,. Medical aspects of the chewing of khat leaves. Bulletin of World Health Organization (1972). 47, 21-29.
[6] A. J Giannini, H. Burge, J. M Shaheen , W. A. Pnce, Khat: another drug of abuse? Journal of Psychoactive Drugs (1986). 18, 155-158.
[7] Y .Gendron, C.H .Ardouin, J. Martine. Accidents cardio vasculaires aigus declenches par le khat. Medicine Tropical (1977). 37, 69-72 .
[8] Mumtaz Ahmad. Role of Plain X-Ray KUB and Renal Ultrasound in evaluation Of Renal Colic. A.P.M.C Vol: 4 No.2 July-December 2010
[9] Ahmed Al-Motarreb, Kathryn Baker and Kenneth J Broadley Khat: pharmacological and Medical Aspects and its Social Use in Yemen Phytother. Res. 16, 403–413 (2002)
[10] A. D Krikorian, Khat and its use: an historical perspective. Journal of Ethnopharmacology (1984). 12, 115-178
[11] A.A .Nasher, A.A .Al-Qiribi, M.A Ghafoor, Murray-Lyon IM. Khat chewing and bladder neck dysfunction a randomized controlled trail of alpha -1- adrenergic blocked. Br J Urol 1995; 75:597–98.
[12] S.W .Toennes, S. Harder, M .Schramm, C. Niess, G.F. Kauert: Pharmaco kinetics of cathinone, cathine and norephedrine after the chewing of khatleaves. Br J Clin Pharmacol 2003, 56(1):125–130.
[13] P .Kalix: Pharmacological properties of the stimulant khat. Pharmacol Ther1990, 48(3):397–416.
[14] L. Cleary, J.R .Docherty: Actions of amphetamine derivatives and cathinoneat the noradrenaline transporter. Eur J Pharmacol 2003, 476(1–2):31–34
[15] R.B. Rothman, N Vu, J.S Partilla, B.L .Roth, S.J .Hufeisen, Compton-Toth B.A, J.Birkes, R .Young, R.A. Glennon: In vitro characterization of ephedrine-related stereo isomers at biogenic amine transporters and the receptor omereveals selective actions as norepinephrine transporter substrates.J Pharmacol Exp Ther 2003, 307(1):138–145
[16] R.A Glennon, S.M Liebowitz: Serotonin receptor affinity of cathinone andrelated analogues. J Med Chem 1982, 25(4):393–397
[17] N.A Hassan, A.A Gunaid, F.M. El-Khally, M.Y Al-Noami, I.M Murray-Lyon: Khat chewing and arterial blood pressure. A randomized controlled clinical trial of alpha-1 and selective beta-1 adrenoceptor blockade. Saudi Med J 2005, 26(4):537–541
[18] A.A Nasher, A.A Qirbi, M.A Ghafoor, A .Catterall, A. Thompson, J.W.A Ramsay, I.M. Murray-Lyon. Khat chewing and neck bladder dysfunction. A randomized controlled trial of a1 adrenergic blockade. Br J Urol 1995; 75: 597–598
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  • APA Style

    Elsafi Ahmed Abdalla, Caroline Edward Ayad, Amin Mohsen Amer, Amel AlGadal. (2014). Characterization of Urinary Bladder in Khat Chewing Yemeni Students Using Ultrasonography. International Journal of Medical Imaging, 2(2), 10-13. https://doi.org/10.11648/j.ijmi.20140202.11

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    ACS Style

    Elsafi Ahmed Abdalla; Caroline Edward Ayad; Amin Mohsen Amer; Amel AlGadal. Characterization of Urinary Bladder in Khat Chewing Yemeni Students Using Ultrasonography. Int. J. Med. Imaging 2014, 2(2), 10-13. doi: 10.11648/j.ijmi.20140202.11

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    AMA Style

    Elsafi Ahmed Abdalla, Caroline Edward Ayad, Amin Mohsen Amer, Amel AlGadal. Characterization of Urinary Bladder in Khat Chewing Yemeni Students Using Ultrasonography. Int J Med Imaging. 2014;2(2):10-13. doi: 10.11648/j.ijmi.20140202.11

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  • @article{10.11648/j.ijmi.20140202.11,
      author = {Elsafi Ahmed Abdalla and Caroline Edward Ayad and Amin Mohsen Amer and Amel AlGadal},
      title = {Characterization of Urinary Bladder in Khat Chewing Yemeni Students Using Ultrasonography},
      journal = {International Journal of Medical Imaging},
      volume = {2},
      number = {2},
      pages = {10-13},
      doi = {10.11648/j.ijmi.20140202.11},
      url = {https://doi.org/10.11648/j.ijmi.20140202.11},
      eprint = {https://article.sciencepublishinggroup.com/pdf/10.11648.j.ijmi.20140202.11},
      abstract = {Khat is a natural stimulant from the Catha Edulis plant and is cultivated in the Republic of Yemen and certain areas of East Africa. Khat produces a modest degree of euphoria and slight hypomania. It results in insomnia and appears to improve the users' alertness and concentration. The main objective of this study was to determine ultrasound findings of urinary bladder among Yemeni khat chewers higher education students. Fifty khat chewers volunteers from higher Education levels were selected as cases, and twenty non-khat chewer volunteers at University level serving as control group. All of them were undergone urinary bladder ultrasound scan. This study revealed that the high frequency of students who chewed khat were from Dhamar area. The study showed that there is a linear relationship between the urinary bladder wall thickness and chewing Khat for years and hours and the residual urine volume is greater in students who chewed the Khat than the control group. Correlation is significant at the P=0.000 for chewing Khat for years and hours.},
     year = {2014}
    }
    

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    T1  - Characterization of Urinary Bladder in Khat Chewing Yemeni Students Using Ultrasonography
    AU  - Elsafi Ahmed Abdalla
    AU  - Caroline Edward Ayad
    AU  - Amin Mohsen Amer
    AU  - Amel AlGadal
    Y1  - 2014/03/10
    PY  - 2014
    N1  - https://doi.org/10.11648/j.ijmi.20140202.11
    DO  - 10.11648/j.ijmi.20140202.11
    T2  - International Journal of Medical Imaging
    JF  - International Journal of Medical Imaging
    JO  - International Journal of Medical Imaging
    SP  - 10
    EP  - 13
    PB  - Science Publishing Group
    SN  - 2330-832X
    UR  - https://doi.org/10.11648/j.ijmi.20140202.11
    AB  - Khat is a natural stimulant from the Catha Edulis plant and is cultivated in the Republic of Yemen and certain areas of East Africa. Khat produces a modest degree of euphoria and slight hypomania. It results in insomnia and appears to improve the users' alertness and concentration. The main objective of this study was to determine ultrasound findings of urinary bladder among Yemeni khat chewers higher education students. Fifty khat chewers volunteers from higher Education levels were selected as cases, and twenty non-khat chewer volunteers at University level serving as control group. All of them were undergone urinary bladder ultrasound scan. This study revealed that the high frequency of students who chewed khat were from Dhamar area. The study showed that there is a linear relationship between the urinary bladder wall thickness and chewing Khat for years and hours and the residual urine volume is greater in students who chewed the Khat than the control group. Correlation is significant at the P=0.000 for chewing Khat for years and hours.
    VL  - 2
    IS  - 2
    ER  - 

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Author Information
  • Sudan University of Science and Technology, College of Medical Radiological Science, Khartoum, Sudan

  • Sudan University of Science and Technology, College of Medical Radiological Science, Khartoum, Sudan

  • Radiology Department, Yemen-Sana’a, Ultrasound Clinic, Sana, Yemen

  • Sudan University of Science and Technology, College of Medical Radiological Science, Khartoum, Sudan

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