International Journal of Medical Imaging

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Added Value of Fetal Magnetic Resonance Imaging in Diagnosis of Central Nervous System Congenital Anomalies in Egyptian Population

Received: 02 December 2018    Accepted: 19 December 2018    Published: 23 January 2019
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Abstract

CNS anomalies are the second most frequent type of congenital anomalies. It is important to diagnose them as early as possible due to poor outcome. The aim of the study is to assess the role of magnetic resonance imaging in evaluation of congenital anomalies of central nervous system. This study included 80 pregnant women with suspected congenital CNS anomalies. All patients had been examined by 2D ultrasound and MRI. The majority of anomalies in the current study were anencephaly, hydrocephalus with aqueductal stenosis and Chiari malformation . Twenty percentage of brain anomalies was associated with meningioceles. A significant difference was detected in both aqueductal stenosis and dandy walker as regards history of consanguinity. The results were compared with post natal clinical assessment and MRI. It is concluded that fetal MRI is becoming an increasingly important tool in diagnosis of brain abnormalities suspected on the basis of family history or fetal sonography (with equivocal data), with continuing improvements in technology for better improvement of postnatal outcome. BPD = Biparietal diameter, CNS = Central nervous system, EFW = Expected fetal body weight, FL = Femur length, FOV = Field of view, MRI = Magnetic resonance imaging, N= Number, SD = Standard deviation, Ssfp= Steady-state free percession, ST= Slice thickness, TE =time of echo, TR=time of repetition, T2WI=T2 weighted image, US=ultrasound.

DOI 10.11648/j.ijmi.20180604.12
Published in International Journal of Medical Imaging (Volume 6, Issue 4, December 2018)
Page(s) 40-48
Creative Commons

This is an Open Access article, distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution and reproduction in any medium or format, provided the original work is properly cited.

Copyright

Copyright © The Author(s), 2024. Published by Science Publishing Group

Keywords

Fetal MRI, CNS Anomalies, Congenital, Ultrasound, Prenatal

References
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[3] Iles S: Normal pregnancy and antenatal care. In: Symonds EM, Symonds I, and Arulkumaran S. (Eds): Essential Obstetrics and Gynecology 3rd edition. E-Book Elsevier Health Sciences, China, 2013. P.85.
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[8] Wilson R, Gagnon A, Audibert F, et al: Prenatal diagnosis procedures and techniques to obtain a diagnostic fetal specimen or tissue: maternal and fetal risks and benefits. Journal of Obstetrics and Gynecology Canada, 2015; 37(7):656-668.
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Author Information
  • Radio-diagnosis & Medical Imaging Department, Faculty of Medicine, Tanta University, Tanta, Egypt

  • Radio-diagnosis & Medical Imaging Department, Faculty of Medicine, Tanta University, Tanta, Egypt

  • Gynecology and Obstetrics Department, Faculty of Medicine, Tanta University, Tanta, Egypt

  • Radio-diagnosis & Medical Imaging Department, Faculty of Medicine, Tanta University, Tanta, Egypt

Cite This Article
  • APA Style

    Alaa Mohamed Reda, Rania Essam-El-Dein Mohamed Ali, Hesham Abdel Aziz Salem, Khaled Esmail El-Shafey. (2019). Added Value of Fetal Magnetic Resonance Imaging in Diagnosis of Central Nervous System Congenital Anomalies in Egyptian Population. International Journal of Medical Imaging, 6(4), 40-48. https://doi.org/10.11648/j.ijmi.20180604.12

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    ACS Style

    Alaa Mohamed Reda; Rania Essam-El-Dein Mohamed Ali; Hesham Abdel Aziz Salem; Khaled Esmail El-Shafey. Added Value of Fetal Magnetic Resonance Imaging in Diagnosis of Central Nervous System Congenital Anomalies in Egyptian Population. Int. J. Med. Imaging 2019, 6(4), 40-48. doi: 10.11648/j.ijmi.20180604.12

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    AMA Style

    Alaa Mohamed Reda, Rania Essam-El-Dein Mohamed Ali, Hesham Abdel Aziz Salem, Khaled Esmail El-Shafey. Added Value of Fetal Magnetic Resonance Imaging in Diagnosis of Central Nervous System Congenital Anomalies in Egyptian Population. Int J Med Imaging. 2019;6(4):40-48. doi: 10.11648/j.ijmi.20180604.12

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  • @article{10.11648/j.ijmi.20180604.12,
      author = {Alaa Mohamed Reda and Rania Essam-El-Dein Mohamed Ali and Hesham Abdel Aziz Salem and Khaled Esmail El-Shafey},
      title = {Added Value of Fetal Magnetic Resonance Imaging in Diagnosis of Central Nervous System Congenital Anomalies in Egyptian Population},
      journal = {International Journal of Medical Imaging},
      volume = {6},
      number = {4},
      pages = {40-48},
      doi = {10.11648/j.ijmi.20180604.12},
      url = {https://doi.org/10.11648/j.ijmi.20180604.12},
      eprint = {https://download.sciencepg.com/pdf/10.11648.j.ijmi.20180604.12},
      abstract = {CNS anomalies are the second most frequent type of congenital anomalies. It is important to diagnose them as early as possible due to poor outcome. The aim of the study is to assess the role of magnetic resonance imaging in evaluation of congenital anomalies of central nervous system. This study included 80 pregnant women with suspected congenital CNS anomalies. All patients had been examined by 2D ultrasound and MRI. The majority of anomalies in the current study were anencephaly, hydrocephalus with aqueductal stenosis and Chiari malformation . Twenty percentage of brain anomalies was associated with meningioceles. A significant difference was detected in both aqueductal stenosis and dandy walker as regards history of consanguinity. The results were compared with post natal clinical assessment and MRI. It is concluded that fetal MRI is becoming an increasingly important tool in diagnosis of brain abnormalities suspected on the basis of family history or fetal sonography (with equivocal data), with continuing improvements in technology for better improvement of postnatal outcome. BPD = Biparietal diameter, CNS = Central nervous system, EFW = Expected fetal body weight, FL = Femur length, FOV = Field of view, MRI = Magnetic resonance imaging, N= Number, SD = Standard deviation, Ssfp= Steady-state free percession, ST= Slice thickness, TE =time of echo, TR=time of repetition, T2WI=T2 weighted image, US=ultrasound.},
     year = {2019}
    }
    

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  • TY  - JOUR
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    AU  - Alaa Mohamed Reda
    AU  - Rania Essam-El-Dein Mohamed Ali
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    JO  - International Journal of Medical Imaging
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    AB  - CNS anomalies are the second most frequent type of congenital anomalies. It is important to diagnose them as early as possible due to poor outcome. The aim of the study is to assess the role of magnetic resonance imaging in evaluation of congenital anomalies of central nervous system. This study included 80 pregnant women with suspected congenital CNS anomalies. All patients had been examined by 2D ultrasound and MRI. The majority of anomalies in the current study were anencephaly, hydrocephalus with aqueductal stenosis and Chiari malformation . Twenty percentage of brain anomalies was associated with meningioceles. A significant difference was detected in both aqueductal stenosis and dandy walker as regards history of consanguinity. The results were compared with post natal clinical assessment and MRI. It is concluded that fetal MRI is becoming an increasingly important tool in diagnosis of brain abnormalities suspected on the basis of family history or fetal sonography (with equivocal data), with continuing improvements in technology for better improvement of postnatal outcome. BPD = Biparietal diameter, CNS = Central nervous system, EFW = Expected fetal body weight, FL = Femur length, FOV = Field of view, MRI = Magnetic resonance imaging, N= Number, SD = Standard deviation, Ssfp= Steady-state free percession, ST= Slice thickness, TE =time of echo, TR=time of repetition, T2WI=T2 weighted image, US=ultrasound.
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