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Pathophysiology Prevention and Management of Chronic Neurogenic Constipation in Adults

Received: 1 June 2013    Accepted:     Published: 30 June 2013
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Abstract

Neurogenic constipation occurs most commonly after spinal cord injury, in multiple sclerosis and in Parkinson`s disease. Slow colonic transit time is a major disorder. Patients also develop pelvic floor dysfunction. Spinal cord patients are unable to defecate voluntarily due to the loss of the rectal fullness sensation and they depend on the spinal reflexes. Obstructed defecation in upper motor neuron spinal cord injury and in Parkinson`s disease is a result of inability to relax the pelvic floor muscles, whereas in the lower type of injury it is due to hyporeactivity of the rectum. In multiple sclerosis it is a combination of lesions from different levels of the nervous system. In diagnosis, neurological and proctologic examinations are required followed by colonic transit time, defecography and anorectal manometry. Most of the patients respond positively on medical treatment. However, a small group of them requires surgical treatment in the form of either colostomy or ileostomy.

Published in Science Journal of Clinical Medicine (Volume 2, Issue 4)
DOI 10.11648/j.sjcm.20130204.11
Page(s) 122-128
Creative Commons

This is an Open Access article, distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution and reproduction in any medium or format, provided the original work is properly cited.

Copyright

Copyright © The Author(s), 2024. Published by Science Publishing Group

Keywords

Neurogenic Constipation, Pathophysiology, Prevention, Management

References
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Cite This Article
  • APA Style

    Jacek Hermann, Sławomir Michalak, Michał Dopierała, Dariusz Tertoń, Michał Drews. (2013). Pathophysiology Prevention and Management of Chronic Neurogenic Constipation in Adults. Science Journal of Clinical Medicine, 2(4), 122-128. https://doi.org/10.11648/j.sjcm.20130204.11

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    ACS Style

    Jacek Hermann; Sławomir Michalak; Michał Dopierała; Dariusz Tertoń; Michał Drews. Pathophysiology Prevention and Management of Chronic Neurogenic Constipation in Adults. Sci. J. Clin. Med. 2013, 2(4), 122-128. doi: 10.11648/j.sjcm.20130204.11

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    AMA Style

    Jacek Hermann, Sławomir Michalak, Michał Dopierała, Dariusz Tertoń, Michał Drews. Pathophysiology Prevention and Management of Chronic Neurogenic Constipation in Adults. Sci J Clin Med. 2013;2(4):122-128. doi: 10.11648/j.sjcm.20130204.11

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  • @article{10.11648/j.sjcm.20130204.11,
      author = {Jacek Hermann and Sławomir Michalak and Michał Dopierała and Dariusz Tertoń and Michał Drews},
      title = {Pathophysiology Prevention and Management of Chronic Neurogenic Constipation in Adults},
      journal = {Science Journal of Clinical Medicine},
      volume = {2},
      number = {4},
      pages = {122-128},
      doi = {10.11648/j.sjcm.20130204.11},
      url = {https://doi.org/10.11648/j.sjcm.20130204.11},
      eprint = {https://article.sciencepublishinggroup.com/pdf/10.11648.j.sjcm.20130204.11},
      abstract = {Neurogenic constipation occurs most commonly after spinal cord injury, in multiple sclerosis and in Parkinson`s disease. Slow colonic transit time is a major disorder. Patients also develop pelvic floor dysfunction. Spinal cord patients are unable to defecate voluntarily due to the loss of the rectal fullness sensation and they depend on the spinal reflexes. Obstructed defecation in upper motor neuron spinal cord injury and in Parkinson`s disease is a result of inability to relax the pelvic floor muscles, whereas in the lower type of injury it is due to hyporeactivity of the rectum. In multiple sclerosis it is a combination of lesions from different levels of the nervous system. In diagnosis, neurological and proctologic examinations are required followed by colonic transit time, defecography and anorectal manometry. Most of the patients respond positively on medical treatment. However, a small group of them requires surgical treatment in the form of either colostomy or ileostomy.},
     year = {2013}
    }
    

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    T1  - Pathophysiology Prevention and Management of Chronic Neurogenic Constipation in Adults
    AU  - Jacek Hermann
    AU  - Sławomir Michalak
    AU  - Michał Dopierała
    AU  - Dariusz Tertoń
    AU  - Michał Drews
    Y1  - 2013/06/30
    PY  - 2013
    N1  - https://doi.org/10.11648/j.sjcm.20130204.11
    DO  - 10.11648/j.sjcm.20130204.11
    T2  - Science Journal of Clinical Medicine
    JF  - Science Journal of Clinical Medicine
    JO  - Science Journal of Clinical Medicine
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    EP  - 128
    PB  - Science Publishing Group
    SN  - 2327-2732
    UR  - https://doi.org/10.11648/j.sjcm.20130204.11
    AB  - Neurogenic constipation occurs most commonly after spinal cord injury, in multiple sclerosis and in Parkinson`s disease. Slow colonic transit time is a major disorder. Patients also develop pelvic floor dysfunction. Spinal cord patients are unable to defecate voluntarily due to the loss of the rectal fullness sensation and they depend on the spinal reflexes. Obstructed defecation in upper motor neuron spinal cord injury and in Parkinson`s disease is a result of inability to relax the pelvic floor muscles, whereas in the lower type of injury it is due to hyporeactivity of the rectum. In multiple sclerosis it is a combination of lesions from different levels of the nervous system. In diagnosis, neurological and proctologic examinations are required followed by colonic transit time, defecography and anorectal manometry. Most of the patients respond positively on medical treatment. However, a small group of them requires surgical treatment in the form of either colostomy or ileostomy.
    VL  - 2
    IS  - 4
    ER  - 

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Author Information
  • Chair and Department of General Surgery, Gastroenterological Oncological Surgery and Plastic Surgery, Poznań University of Medical Sciences, Poznań, Poland

  • Chair and Department of Neurology, Poznań University of Medical Sciences, Poznań, Poland

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