Prevalence of Hyperuricemia (HU) in Arterial Hypertension
Science Journal of Clinical Medicine
Volume 4, Issue 4, July 2015, Pages: 76-79
Received: May 29, 2015; Accepted: Jun. 15, 2015; Published: Jul. 4, 2015
Views 3201      Downloads 72
Bâ Hamidou Oumar, University Hospital «Gabriel Touré», Cardiology, Bamako, Mali
Menta Ichaka, University Hospital «Gabriel Touré», Cardiology, Bamako, Mali
Maiga Asmaou Kéita, University Hospital «Le Luxembourg », Cardiology, Bamako, Mali
Daou Adama, National support center for the fight against the disease, Bamako, Mali
Diall Ilo Bella, University Hospital «Point G», Cardiology, Bamako, Mali
Coulibaly Souleymane, University Hospital «Point G», Cardiology, Bamako, Mali
Doumbia Coumba Thiam, National support center for the fight against the disease, Bamako, Mali
Daffé Sanoussi, National support center for the fight against the disease, Bamako, Mali
Sidibé Noumou, University Hospital «Gabriel Touré», Cardiology, Bamako, Mali
Sangaré Ibrahima, University Hospital «Gabriel Touré», Cardiology, Bamako, Mali
Millogo Georges Rosario Christian, University Hospital «Yalgado Ouedraogo», Cardiology, Ouagadougou, Burkina, Faso
Touré Mamadou, University Hospital «Gabriel Touré», Cardiology, Bamako, Mali
Sidibé Salimata, University Hospital «Point G», Cardiology, Bamako, Mali
Diarra Mamadou Bocary, National support center for the fight against the disease, Bamako, Mali
Article Tools
Follow on us
Introduction: Hyperuricemia constitutes a risk for many organs and its prevalence is high ranging from 15-20% up to 35% in developing countries. HU relation to arterial hypertension was pointed out in the end of the XIX century and is recognized as independent cardiovascular risk factor. Thus HU is less studied in our environment which justifies our work to determine prevalence and with HU associated factors among hypertensive patients followed in the Cardiology department in the Mother Child Hospital “Le Luxembourg”. Methodology: It’s was a cross-sectional study in the Mother-Child Hospital “Le Luxembourg” in Bamako. All patients with complete labor tests were included making a sample of 51 hypertensive outpatients seen from July 2010 to January 2011. For any included patient, socio-demographic and biological variables were collected. In the same way a chest radiography, an ECG and an echocardiography were realized. Patients were asked about their knowledge about HU Hyperuricemia was defined as an uricemia > 420 μmol/l for men and 360 μmol/l for women. Microsoft Excel 2007 was used to gather data and SPSS version 12 to perform analyzes. Results: Mean age of the sample was 56,35 years, the sex-ratio Male: Female 0,76. Hyperuricemia, hypercreatininemia and hyperglycemia were found respectively in 66,7,33,3% and 23,5% of the cases. 78,4% of the patients had stated to have heard about hyperuricemia, 27,5% knew their hyperuricemia. The socio-demographic characteristics did not present a statistically significant difference. Conclusion: Hyperuricemia as a cardiovascular risk factor, had to be researched and managed more agressively. The very high proportion of patients with a hyperuricemia requires to detect it among hypertensive patients, to carry out an early treatment and thus to reduce the cardiovascular risk of the patient.
Hypertension, Hyperuricemia, Cardiology, Bamako
To cite this article
Bâ Hamidou Oumar, Menta Ichaka, Maiga Asmaou Kéita, Daou Adama, Diall Ilo Bella, Coulibaly Souleymane, Doumbia Coumba Thiam, Daffé Sanoussi, Sidibé Noumou, Sangaré Ibrahima, Millogo Georges Rosario Christian, Touré Mamadou, Sidibé Salimata, Diarra Mamadou Bocary, Prevalence of Hyperuricemia (HU) in Arterial Hypertension, Science Journal of Clinical Medicine. Vol. 4, No. 4, 2015, pp. 76-79. doi: 10.11648/j.sjcm.20150404.12
Scorr JT. Asymptomatic hyperuricaemia. British Medical Journal (Clinical research ed). 1987;294(6578):987-988.
Snaith ML. Gout, Hyperuricaemia, And Crystal Arthritis BMJ : British Medical Journal. 1995;310(6978):521-524.
Slot O. Hyperuricemia (Abstract). Ugeskr Laeger. 1994 ;156(16):2396-401.
Feig DI, Kang DH, Johnson RJ., Uric acid and cardiovascular risk. N Engl J Med 2008; 359:1811-21.
Kim SY, Guevara JP, Kim KM, Choi HK, Heitjan DF, Albert DA. Hyperuricemia and Risk of Stroke: A Systematic Review and Meta-analysis. Arthritis Rheum. 2009 July 15; 61(7): 885–892 doi:10.1002/art.24612
Krishnan E. Hyperuricemia and incident heart failure. Circ Heart Fail. 2009 November ; 2(6): 556–562.
Hurtes X, Meria P. Atteintes uro-néphrologiques des hyperuricémie. Presse Med (2011), doi:10.1016/j.lpm.2011.05.006
Mijiyawa M, Bouglouga OE. Hyperuricémie et goutte en zone intertropicale. Revue du rhumatisme 2003 (70):152-156
Conen D, Wietlisbach V, Bovet P, Shamlaye C, Riesen W, Paccaud F and Burnier M. Prevalence of hyperuricemia and relation of serum uric acid with cardiovascular risk factors in a developing country. BMC Public Health 2004, 4:9.
Hadjeres S, Saudan P. L’Hyper uricémie dans l’hypertension artérielle et l’insuffisance rénale : facteur causal ou épiphénomène? Revue médicale Suisse, numéro : 3192 : 1- 6. Visité mai 2011. sid=33881
HØieggen et al: Serum uric acid in the LIFE study. Kidney International 2004; 65: 1041-49
Culleton BF, Larson MG, Kannel WB, Levy D., Serum uric acid and risk for cardiovascular disease and death:The Framingham heart study. Ann Intern Med 1999; 131:7-13.
Allard A, Bardin T. Hyperuricémie et risque cardiovasculaire (abstract ). L'actualité rhumatologique 2009. Doi : 10.1016/B978-2-8101-0150-4.00011-4
Mene P, Punzo G. Uric acid: Bystander or culprit in hypertension and progressive renal disease? (abstract). J Hypertension 2008; 26: 2085 – 92
Deléaval P, Burnier M. L’hyperuricémie dans l’hypertension artérielle: quelle implication? Revue Médicale Suisse 2005; 32. Accessed on 22.04.15
Chen et al. Relationship between hyperuricemia and metabolic syndrome. J Zhejiang Univ Sci B 2007; 8(8):593-598
Sui X, Church TS, Meriwether RA, Lobelo F and Blair SN. Uric Acid and the Development of Metabolic Syndrome in Women and Men. Metabolism. 2008;57(6): 845–852.
Science Publishing Group
1 Rockefeller Plaza,
10th and 11th Floors,
New York, NY 10020
Tel: (001)347-983-5186