Basic C-peptidemia and Diabetic Patients Classification
Science Journal of Clinical Medicine
Volume 6, Issue 6, November 2017, Pages: 116-119
Received: Sep. 1, 2017; Accepted: Sep. 30, 2017; Published: Nov. 13, 2017
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Authors
Deh Zhou Patricia, Laboratory of Histology-Embryology and Cytogenetics, UFR-Medical Sciences, University Félix Houphouët-Boigny, Abidjan, Côte d’Ivoire
Koffi Dago Pierre, Department of Endocrinology- Diabetology, University Teaching Hospital-Yopougon, Abidjan, Côte d’Ivoire
Kouassi Joël-Brice, Laboratory of Biochemistry, UFR-Medical Sciences, University Félix Houphouët-Boigny, Abidjan, Côte d’Ivoire
Montéomo Gnaté François, Laboratory of Animal Physiology, Pharmacology - Pharmacopoeia, UFR-Nature Sciences, University Nangui-Abrogoua, Abidjan, Côte d’Ivoire
Kouassi Franck, Department of Endocrinology- Diabetology, University Teaching Hospital-Yopougon, Abidjan, Côte d’Ivoire
Yao Assita, Department of Endocrinology- Diabetology, University Teaching Hospital-Yopougon, Abidjan, Côte d’Ivoire
Hué Adélaïde, Department of Endocrinology- Diabetology, University Teaching Hospital-Yopougon, Abidjan, Côte d’Ivoire
Abodo Jacko Rhedoor, Department of Endocrinology- Diabetology, University Teaching Hospital-Yopougon, Abidjan, Côte d’Ivoire
Yapi Ahoua, Laboratory of Animal Biology, UFR-Biosciences, University Félix Houphouët-Boigny, Abidjan, Côte d’Ivoire
Lokrou Adrien, Department of Endocrinology- Diabetology, University Teaching Hospital-Yopougon, Abidjan, Côte d’Ivoire
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Abstract
Diabetes is a real public health problem in the world. In Africa in general and in Côte d'Ivoire in particular, the management of diabetes is complicated by socio-economic difficulties. After the diagnosis of diabetes, its typing is carried out on the basis of clinical criteria. With the discovery of many subgroups of diabetes especially in Africa, the classification of diabetes is made difficult. This difficulty may raise questions about the adequacy of the therapeutic treatment of patients. The purpose of this study was to study mainly the contribution of basal C-peptidemia in the typing of diabetic subjects. The material concerned a population of 220 diabetics who carried out their peptide C assay and monitored at the Yopougon-ABIDJAN University and Hospital Center. Basal C-Peptidemia was assayed by competitive radio-immunoassay using the kit CIS –BIO Shering. The results revealed that the classification based on clinical signs was improved after the C-peptide assay. Indeed, after C-peptidemia, type 1 diabetics with low C-peptidemia (<0.5 ng/ml) and type 2 diabetics with normal C-peptidemia (0.5 ng/ml to 3 ng/ml). In conclusion, the determination of peptide C appears as an undeniable tool for better classification of diabetic patients. The results of C-peptidemia would direct the practitioner towards a more adequate treatment in the patients studied.
Keywords
Diabetes, C-peptide, Classification, Type 1 Diabetes, Type 2 Diabetes, Insulin-secreting Function
To cite this article
Deh Zhou Patricia, Koffi Dago Pierre, Kouassi Joël-Brice, Montéomo Gnaté François, Kouassi Franck, Yao Assita, Hué Adélaïde, Abodo Jacko Rhedoor, Yapi Ahoua, Lokrou Adrien, Basic C-peptidemia and Diabetic Patients Classification, Science Journal of Clinical Medicine. Vol. 6, No. 6, 2017, pp. 116-119. doi: 10.11648/j.sjcm.20170606.14
Copyright
Copyright © 2017 Authors retain the copyright of this article.
This article is an open access article distributed under the Creative Commons Attribution License (http://creativecommons.org/licenses/by/4.0/) which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
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