Five Years Trend of Helicobacter Pylori Infection Among Dyspeptic Patients in Asella Teaching and Referral Hospital, Arsi University, Ethiopia
Science Journal of Clinical Medicine
Volume 7, Issue 5, September 2018, Pages: 37-40
Received: Oct. 9, 2018;
Accepted: Nov. 29, 2018;
Published: Dec. 18, 2018
Views 759 Downloads 101
Million Getachew Mesfun, Department of Medical Laboratory Science, college of Health Sciences, Arsi University, Asella, Ethiopia
Shimels Teshome, Asella Teaching and Referral Hospital, Arsi University, Asella, Ethiopia
Desalegn Alemu, Asella Teaching and Referral Hospital, Arsi University, Asella, Ethiopia
Follow on us
Infectious diseases such as H. pylori infection are major public health problems in Ethiopia. Even though there are a considerably large number of dyspeptic patients in Asella teaching and referral hospital, there is no study done to assess the trend of H. pylori infection among dyspeptic patients. The objective of this study was to assess a five years trend of H. pylori infection among dyspeptic patients in Asella teaching and referral hospital. A retrospective cross-sectional study design was used to assess the trend of H. pylori infection from January 1, 2013 until October 30, 2017 among dyspeptic patients by counting stool antigen test results from the laboratory log book. It was found that a total of 9,493 dyspeptic patients with the mean age of 33.9 (SD+15.1) years were test for H. pylori infection in the last five years in Asella teaching and referral hospital. The total prevalence of H. pylori was 1,444 (15.2%) in which 863 (59.8%) of them were females and 581 (40.2%) were males. There was a fluctuating trend of H. pylori with annual total cases of H. pylori ranged from 19.3% in 2017 to 6.1% in 2015. The study showed that there was low prevalence of H. pylori infection among dyspeptic patients in Asella teaching and referral hospital, Ethiopia. The low prevalence reported from this study could be also due to the quality of the test kits, therefore, there is a need to validate the test kits used by the hospital laboratory.
H. pylori, Trend, Dyspeptic Patients, Asella, Ethiopia
To cite this article
Million Getachew Mesfun,
Five Years Trend of Helicobacter Pylori Infection Among Dyspeptic Patients in Asella Teaching and Referral Hospital, Arsi University, Ethiopia, Science Journal of Clinical Medicine.
Vol. 7, No. 5,
2018, pp. 37-40.
Copyright © 2018 Authors retain the copyright of this article.
This article is an open access article distributed under the Creative Commons Attribution License (http://creativecommons.org/licenses/by/4.0/
) which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
Celli JP, Turner BS, Afdhal NH, et al. Helicobacter pylori moves through mucus by reducing mucin viscoelasticity. Proceedings of the National Academy of Sciences. 2009; 106(34): 14321-14326. doi: http:// dx.doi.org/10.1073/pnas.0903438106.
Kusters JG, van Vliet AHM, Kuipers EJ. Pathogenesis of Helicobacter pylori Infection. Clinical Microbiology Reviews. 2006; 19(3): 449-490. doi: http://dx.doi. org/10.1128/CMR.00054-05.
Percival SL. The Significance of Helicobacter Pylori Acquisition and the Hygiene Hypothesis. In: Microbiology and Aging: Clinical Manifestations. Totowa, NJ: Humana Press. New York: Springer; 2009; 263-274.
Thomas JE, Dale A, Harding M, Coward WA, Cole TJ, Weaver LT. Helicobacter pylori Colonization in Early Life. Pediatric Research. 1999; 45(2): 218-223. doi: http://dx.doi.org/10.1203/00006450-199902000-00010.
Kusters, J. G., A. H. M. van Vliet, and E. J. Kuipers, Pathogenesis of Helicobacter pylori Infection. Clinical Microbiology Reviews, 2006; 19(3): 449-490. doi: http:// dx.doi.org/10.1128/cmr.00054-05.
Kibru D, Gelaw B, Alemu A, Addis Z. Helicobacter pylori infection and its association with anemia among adult dyspeptic patients attending Butajira Hospital, Ethiopia. BMC Infectious Diseases. 2014; 14(1). doi: http://dx.doi.org/10.1186/s12879-014-0656-3.
Tadesse E, Daka D, Yemane D, Shimelis T. Seroprevalence of Helicobacter pylori infection and its related risk factors in symptomatic patients in southern Ethiopia. BMC Research Notes. 2014; 7(1): 834. doi: http://dx.doi.org/10.1186/1756-0500-7-834.
Mathewos B, Moges B, Dagnew M. Seroprevalence and trend of Helicobacter pylori infection in Gondar University Hospital among dyspeptic patients, Gondar, North West Ethiopia. BMC Research Notes. 2013; 6(1): 346. doi: http://dx.doi.org/10.1186/1756-0500-6-346.
Watanabe M, Ito H, Hosono S, et al. Declining trends in prevalence of Helicobacter pylori infection by birth year in a Japanese population. Cancer Sci. 2015; 106(12): 1738-1743. doi: http://dx.doi. org/10.1111/cas.12821
Workineh M, Andargie D. A 5-year trend of Helicobacter pylori seroprevalence among dyspeptic patients at Bahir Dar Felege Hiwot Referral Hospital, Northwest Ethiopia. Research and Reports in Tropical Medicine. 2016; Volume 7: 17-22. doi: http://dx.doi. org/10.2147/RRTM.S105361.
Abebaw W, Kibret M, Abera B. Prevalence and Risk Factors of H. pylori from Dyspeptic Patients in Northwest Ethiopia: A Hospital Based Cross-sectional Study. Asian Pacific Journal of Cancer Prevention. 2014; 15(11): 4459-4463. doi: http://dx.doi. org/10.7314/APJCP.2014.15.11.4459.
Negash, M., H. Wondifraw Baynes, and D. Geremew, Helicobacter pylori Infection and Its Risk Factors: A Prospective Cross-Sectional Study in Resource-Limited Settings of Northwest Ethiopia. The Canadian journal of infectious diseases & medical microbiology = Journal canadien des maladies infectieuses et de la microbiologie medicale, 2018. 2018: p. 9463710-9463710.
Asrat D, Nilsson I, Mengistu Y, et al. Prevalence of Helicobacter pylori infection among adult dyspeptic patients in Ethiopia. Ann Trop Med Parasitol. 2004; 98(2): 181-189. doi: http://dx.doi. org/10.1179/000349804225003190.
Lim SH, Kwon J-W, Kim N, et al. Prevalence and risk factors of Helicobacter pylori infection in Korea: Nationwide multicenter study over 13 years. BMC Gastroenterology. 2013; 13(1). doi: http://dx.doi. org/10.1186/1471-230X-13-104.
Moges F. Seroprevalence of Helicobacter pylori in dyspeptic patients and its relationship with HIV infection, ABO blood groups and life style in a university hospital, Northwest Ethiopia. World Journal of Gastroenterology. 2006; 12(12): 1957. doi: http:// dx.doi.org/10.3748/wjg.v12.i12.1957.
Segal I. Persistent low prevalence of Western digestive diseases in Africa: confounding aetiological factors. Gut. 2001; 48(5): 730-732. doi: http://dx.doi. org/10.1136/gut.48.5.730.