Science Journal of Clinical Medicine
Volume 4, Issue 4-1, July 2015, Pages: 26-30
Received: Jun. 22, 2015;
Accepted: Jun. 23, 2015;
Published: Aug. 3, 2015
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T. S. Rekha, Department of Pathology, JSS Medical College, Constituent College of JSS University, Mysore, India
N. M. Nandini, Department of Pathology, JSS Medical College, Constituent College of JSS University, Mysore, India
Introduction: With the increase in the awareness of breast cancer among women, cases of lump in the breast has increased in outpatient department. Fine needle aspiration cytology (FNAC) is the easy, quick and cost effective technique of evaluating breast lump. Objective: The present study, evaluated and compared the modified Masood's cytology index (MCI) with various other cytology grading methods and histopathology. Result: Modified MCI has over all concordance rate of 86%, sensitivity of 86%, specificity of 50%, positive predictive value (PPV) of 93% and negative predictive value (NPV) of 30%. Multiple regression analysis revealed an r2 value of 60%, which was significant. The p-value of anisonucleosis, nucleoli and chromatin pattern were 0.001, 0.05 and 0.02 respectively, which was significant (p-value less than 0.05). Conclusion: Modified MCI will help the cytopathologist to accurately delineate both benign and malignant neoplastic breast lesions into respective categories. This in turn will help the treating surgeon to plan the treatment modality of the patients with lump in the breast. The study recommends that modified MCI method to be routinely incorporated for evaluation of all lump in the breast.
T. S. Rekha,
N. M. Nandini,
Evaluation of Breast Neoplastic Lesions by Different Cytology Grading Methods, Science Journal of Clinical Medicine. Special Issue: Latest Different Concepts of Gynaecology.
Vol. 4, No. 4-1,
2015, pp. 26-30.
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