International Journal of Psychological and Brain Sciences

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Intravascular Mechanical Thrombectomy for a Patient with Systemic Lupus Erythematosus and Acute Cerebral Infarction with Antiphospholipid Syndrome

Received: 19 January 2020    Accepted: 13 February 2020    Published: 20 February 2020
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Abstract

Systemic lupus erythematosus (SLE) is a diffuse connective tissue disease that is characterized by autoimmune-mediated inflammation. Antiphospholipid syndrome (APS) is a non-inflammatory autoimmune disease. A 55-year-old female patient was admitted to the hospital due to ‘sudden speech insufficiency and aggravation of 5 h’. The patient developed sudden dizziness, facial numbness, and slurred speech and was transported to the emergency department in a local hospital, and was diagnosed ‘cerebral infarction’ after a CT examination. According to the medical records, the patient developed SLE at the age of 25. CT showed low density lesions of the left pons and occipital lobe; emergent MRI showed bilateral infarction in the cerebellum and brainstem, and magnetic resonance angiography (MRA) showed upper basilar artery occlusion. Ischemic stroke was diagnosed and NIHSS scored 30. The occluded artery was successfully recanalized with endovascular mechanical thrombectomy. Modified thrombolysis in cerebral infarction (mTICI) blood flow perfusion grade was grade 3. The case is the first one in the literature that acute ischemic stroke related to SLE vasculitis and antiphospholipid syndrome was treated successfully with endovascular mechanical thrombectomy.

DOI 10.11648/j.ijpbs.20200501.13
Published in International Journal of Psychological and Brain Sciences (Volume 5, Issue 1, February 2020)
Page(s) 21-27
Creative Commons

This is an Open Access article, distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution and reproduction in any medium or format, provided the original work is properly cited.

Copyright

Copyright © The Author(s), 2024. Published by Science Publishing Group

Keywords

Thrombolysis, Stroke, Systemic Lupus Erythematosus, Vasculitis

References
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Author Information
  • Department of Neurology, Hefei Second People’s Hospital, Hefei, China

  • Department of Neurology, Hefei Second People’s Hospital, Hefei, China

  • Department of Neurology, The First Affiliated Hospital, University of Science and Technology of China, Hefei, China

  • Department of Neurology, The First Affiliated Hospital, University of Science and Technology of China, Hefei, China

  • Department of Neurology, Hefei Second People’s Hospital, Hefei, China

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    Jiaxia Li, Shugang Cao, Wei Hu, Yuyou Zhu, Mingwu Xia. (2020). Intravascular Mechanical Thrombectomy for a Patient with Systemic Lupus Erythematosus and Acute Cerebral Infarction with Antiphospholipid Syndrome. International Journal of Psychological and Brain Sciences, 5(1), 21-27. https://doi.org/10.11648/j.ijpbs.20200501.13

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    ACS Style

    Jiaxia Li; Shugang Cao; Wei Hu; Yuyou Zhu; Mingwu Xia. Intravascular Mechanical Thrombectomy for a Patient with Systemic Lupus Erythematosus and Acute Cerebral Infarction with Antiphospholipid Syndrome. Int. J. Psychol. Brain Sci. 2020, 5(1), 21-27. doi: 10.11648/j.ijpbs.20200501.13

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    AMA Style

    Jiaxia Li, Shugang Cao, Wei Hu, Yuyou Zhu, Mingwu Xia. Intravascular Mechanical Thrombectomy for a Patient with Systemic Lupus Erythematosus and Acute Cerebral Infarction with Antiphospholipid Syndrome. Int J Psychol Brain Sci. 2020;5(1):21-27. doi: 10.11648/j.ijpbs.20200501.13

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  • @article{10.11648/j.ijpbs.20200501.13,
      author = {Jiaxia Li and Shugang Cao and Wei Hu and Yuyou Zhu and Mingwu Xia},
      title = {Intravascular Mechanical Thrombectomy for a Patient with Systemic Lupus Erythematosus and Acute Cerebral Infarction with Antiphospholipid Syndrome},
      journal = {International Journal of Psychological and Brain Sciences},
      volume = {5},
      number = {1},
      pages = {21-27},
      doi = {10.11648/j.ijpbs.20200501.13},
      url = {https://doi.org/10.11648/j.ijpbs.20200501.13},
      eprint = {https://download.sciencepg.com/pdf/10.11648.j.ijpbs.20200501.13},
      abstract = {Systemic lupus erythematosus (SLE) is a diffuse connective tissue disease that is characterized by autoimmune-mediated inflammation. Antiphospholipid syndrome (APS) is a non-inflammatory autoimmune disease. A 55-year-old female patient was admitted to the hospital due to ‘sudden speech insufficiency and aggravation of 5 h’. The patient developed sudden dizziness, facial numbness, and slurred speech and was transported to the emergency department in a local hospital, and was diagnosed ‘cerebral infarction’ after a CT examination. According to the medical records, the patient developed SLE at the age of 25. CT showed low density lesions of the left pons and occipital lobe; emergent MRI showed bilateral infarction in the cerebellum and brainstem, and magnetic resonance angiography (MRA) showed upper basilar artery occlusion. Ischemic stroke was diagnosed and NIHSS scored 30. The occluded artery was successfully recanalized with endovascular mechanical thrombectomy. Modified thrombolysis in cerebral infarction (mTICI) blood flow perfusion grade was grade 3. The case is the first one in the literature that acute ischemic stroke related to SLE vasculitis and antiphospholipid syndrome was treated successfully with endovascular mechanical thrombectomy.},
     year = {2020}
    }
    

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    T1  - Intravascular Mechanical Thrombectomy for a Patient with Systemic Lupus Erythematosus and Acute Cerebral Infarction with Antiphospholipid Syndrome
    AU  - Jiaxia Li
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    AU  - Mingwu Xia
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    JF  - International Journal of Psychological and Brain Sciences
    JO  - International Journal of Psychological and Brain Sciences
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    PB  - Science Publishing Group
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    AB  - Systemic lupus erythematosus (SLE) is a diffuse connective tissue disease that is characterized by autoimmune-mediated inflammation. Antiphospholipid syndrome (APS) is a non-inflammatory autoimmune disease. A 55-year-old female patient was admitted to the hospital due to ‘sudden speech insufficiency and aggravation of 5 h’. The patient developed sudden dizziness, facial numbness, and slurred speech and was transported to the emergency department in a local hospital, and was diagnosed ‘cerebral infarction’ after a CT examination. According to the medical records, the patient developed SLE at the age of 25. CT showed low density lesions of the left pons and occipital lobe; emergent MRI showed bilateral infarction in the cerebellum and brainstem, and magnetic resonance angiography (MRA) showed upper basilar artery occlusion. Ischemic stroke was diagnosed and NIHSS scored 30. The occluded artery was successfully recanalized with endovascular mechanical thrombectomy. Modified thrombolysis in cerebral infarction (mTICI) blood flow perfusion grade was grade 3. The case is the first one in the literature that acute ischemic stroke related to SLE vasculitis and antiphospholipid syndrome was treated successfully with endovascular mechanical thrombectomy.
    VL  - 5
    IS  - 1
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