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The Application of Next Generation Sequencing in Forensic DNA Database

Received: 19 May 2017    Accepted:     Published: 20 May 2017
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Abstract

With the developing of standardized forensic DNA profiling and information technology, the forensic DNA database has achieved a big success. By managing、searching and sharing through DNA database, the molecular biology and genetics play a crucial role in individual identification, in the meantime, the DNA database also promote the developing of large-scale forensic DNA testing. In recent years, the arising of second generation sequencing(SGS) has substantially changed the way of genetics research, and varies of platform、kit and system has been developed continuously, many of which has been applied in forensic laboratories. So for,the China National DNA Database has expanded to be the largest one in the world, therefore, the SGS needs to incorporated with the DNA database rather than instead of it. So, the compatibility of SGS-based data with massive PCR-CE data in the database is now becoming a critical problem.in this article, the China National DNA Database is introduced, the advantages of SGS and its possible role in the forensic DNA profiling and databasing are elaborated, and the consistency in data storage and the compatibility in comparing of the SGS-based data within the present DNA database are also discussed.

DOI 10.11648/j.sd.20170504.13
Published in Science Discovery (Volume 5, Issue 4, August 2017)
Page(s) 257-261
Creative Commons

This is an Open Access article, distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution and reproduction in any medium or format, provided the original work is properly cited.

Copyright

Copyright © The Author(s), 2024. Published by Science Publishing Group

Keywords

Forensic DNA Profiling, DNA Database, Second Generation Sequencing, Data Compatibility

References
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Author Information
  • Institute of Forensic Science of Ministry of Public Security, Beijing, China

  • Institute of Forensic Science of Ministry of Public Security, Beijing, China

  • Institute of Forensic Science of Ministry of Public Security, Beijing, China

  • Institute of Forensic Science of Ministry of Public Security, Beijing, China

  • Institute of Forensic Science of Ministry of Public Security, Beijing, China

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  • APA Style

    Zhao Zhao, Wang Le, Li Sheng, Wang Tong, Liu Bing. (2017). The Application of Next Generation Sequencing in Forensic DNA Database. Science Discovery, 5(4), 257-261. https://doi.org/10.11648/j.sd.20170504.13

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    ACS Style

    Zhao Zhao; Wang Le; Li Sheng; Wang Tong; Liu Bing. The Application of Next Generation Sequencing in Forensic DNA Database. Sci. Discov. 2017, 5(4), 257-261. doi: 10.11648/j.sd.20170504.13

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    AMA Style

    Zhao Zhao, Wang Le, Li Sheng, Wang Tong, Liu Bing. The Application of Next Generation Sequencing in Forensic DNA Database. Sci Discov. 2017;5(4):257-261. doi: 10.11648/j.sd.20170504.13

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  • @article{10.11648/j.sd.20170504.13,
      author = {Zhao Zhao and Wang Le and Li Sheng and Wang Tong and Liu Bing},
      title = {The Application of Next Generation Sequencing in Forensic DNA Database},
      journal = {Science Discovery},
      volume = {5},
      number = {4},
      pages = {257-261},
      doi = {10.11648/j.sd.20170504.13},
      url = {https://doi.org/10.11648/j.sd.20170504.13},
      eprint = {https://download.sciencepg.com/pdf/10.11648.j.sd.20170504.13},
      abstract = {With the developing of standardized forensic DNA profiling and information technology, the forensic DNA database has achieved a big success. By managing、searching and sharing through DNA database, the molecular biology and genetics play a crucial role in individual identification, in the meantime, the DNA database also promote the developing of large-scale forensic DNA testing. In recent years, the arising of second generation sequencing(SGS) has substantially changed the way of genetics research, and varies of platform、kit and system has been developed continuously, many of which has been applied in forensic laboratories. So for,the China National DNA Database has expanded to be the largest one in the world, therefore, the SGS needs to incorporated with the DNA database rather than instead of it. So, the compatibility of SGS-based data with massive PCR-CE data in the database is now becoming a critical problem.in this article, the China National DNA Database is introduced, the advantages of SGS and its possible role in the forensic DNA profiling and databasing are elaborated, and the consistency in data storage and the compatibility in comparing of the SGS-based data within the present DNA database are also discussed.},
     year = {2017}
    }
    

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  • TY  - JOUR
    T1  - The Application of Next Generation Sequencing in Forensic DNA Database
    AU  - Zhao Zhao
    AU  - Wang Le
    AU  - Li Sheng
    AU  - Wang Tong
    AU  - Liu Bing
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    DO  - 10.11648/j.sd.20170504.13
    T2  - Science Discovery
    JF  - Science Discovery
    JO  - Science Discovery
    SP  - 257
    EP  - 261
    PB  - Science Publishing Group
    SN  - 2331-0650
    UR  - https://doi.org/10.11648/j.sd.20170504.13
    AB  - With the developing of standardized forensic DNA profiling and information technology, the forensic DNA database has achieved a big success. By managing、searching and sharing through DNA database, the molecular biology and genetics play a crucial role in individual identification, in the meantime, the DNA database also promote the developing of large-scale forensic DNA testing. In recent years, the arising of second generation sequencing(SGS) has substantially changed the way of genetics research, and varies of platform、kit and system has been developed continuously, many of which has been applied in forensic laboratories. So for,the China National DNA Database has expanded to be the largest one in the world, therefore, the SGS needs to incorporated with the DNA database rather than instead of it. So, the compatibility of SGS-based data with massive PCR-CE data in the database is now becoming a critical problem.in this article, the China National DNA Database is introduced, the advantages of SGS and its possible role in the forensic DNA profiling and databasing are elaborated, and the consistency in data storage and the compatibility in comparing of the SGS-based data within the present DNA database are also discussed.
    VL  - 5
    IS  - 4
    ER  - 

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