The Lubricity of Polyvinyl Alcohol and Nano-silica Hydrogel’s Scaffold Fabricated by 3D Printing
Volume 5, Issue 7, December 2017, Pages: 524-528
Received: Dec. 28, 2017;
Published: Dec. 28, 2017
Views 796 Downloads 64
Zhang Yikun, Hubei Provincial Key Laboratory of Green Materials for Light Industry, Hubei University of Technology, Wuhan, China
Wang Hui, Hubei Provincial Key Laboratory of Green Materials for Light Industry, Hubei University of Technology, Wuhan, China
Li Xuefeng, School of Materials and Chemical Engineering, Hubei University of Technology, Wuhan, China
Follow on us
Hydrogel is a macromolecule three-dimensional network made of hydrophilic polymers, which is soft and has good elasticity. Hydrogels have a wide range of potential applications in tissue engineering, drug delivery and biosensors. In this paper can be applied to a biomedical polymer material polyvinyl alcohol as matrix, according to the first forming crosslinking method, using 3D printing to make SiO2/PVA sol forming, and then freeze-melt cross-linking treatment to prepare a physically cross-linked three-dimensional network hydrogel scaffold. The further study found that hydrogel scaffold has high mechanical strength and fine internal structure, the compressive modulus of the hydrogel scaffold can reach more than 2.4 times that of the bulk polyvinyl alcohol hydrogel, and the compression of the scaffold Modulus decreases with increasing porosity of the stent. The tribological properties of the scaffolds show that the scaffold has high lubricity and good stability when rubbed repeatedly, due to the double network hydrogel scaffold has good biological compatibility and adhesion properties, cell culture, cells found on the inner wall of the stent porosity can better growth.
3D Printing, Poly (Vinyl Alcohol), Scaffold, Lubricity
To cite this article
The Lubricity of Polyvinyl Alcohol and Nano-silica Hydrogel’s Scaffold Fabricated by 3D Printing, Science Discovery.
Vol. 5, No. 7,
2017, pp. 524-528.
T H Young, N K Yao, R F Chang, et al, “Evaluation of asymmetric poly (vinyl alcohol) membranes for ues in artifical islets” J. Biomaterials, vol. 17(22), pp. 2139-2145, 1996.
M Oka. “Biomechanics and repair of articular cartilage” J. Journal of Orthopaedic Science, vol. 6(5), pp. 448-456, 2001.
M Oka, Y S Chang, Nakamura T, et al, “Synthetic osteochondral replacement of femoral articular surface” J. Journal of Bone & Joint Surgery, vol. 79(6), pp 1003-1007, 1997.
M Oka, T Noguchi, P Kumar, et al, “Development of an artificial articular cartilage” J. Clinical Materials, vol. 6(4), pp 361-381, 1990.
T Noguchi, T Yamamuro, M Oka, et al, “Poly (vinyl alcohol) hydrogel as an artificial articular cartilage: evaluation of biocompatibility” J. Journal of Applied Biomaterials, vol. 2(2), pp 101-107, 1991.
W Szkowski, D N Ku, H Bersee, et al, “An elastic material for cartilage replacement in an arthritic shoulder joint” J. Biomaterials, vol. 27(8), pp 1534-1541, 2006.
N A Peppas, Y Huang, M Torres Lugo, et al, “Physicochemical foundations and structural design of hydrogels in medicine and biology” J. Annual Review of Biomedical Engineering, vol. 2(1), pp 9-29, 2000.
S E Bakarich, P Balding, R Gorkin, et al, “Printed ionic-covalent entanglement hydrogels from carrageenan and an epoxy amine” J. Rsc Advances, vol. 4(72), pp 38088-38092, 2014.