Whitening Efficacy Evaluation of the Multi-Herb

Lu Yi-na; Yang Ya-di; Lin Meng-gan; Xie Zhi-yong

doi:doi:10.11648/j.sd.20180604.22

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Whitening Efficacy Evaluation of the Multi-Herb

Lu Yi-na, Yang Ya-di, Lin Meng-gan, Xie Zhi-yong

Published in Science Discovery (Volume 6, Issue 4)

Received: 9 August 2018 Accepted: Published: 10 August 2018

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Abstract

The multi-Herb (mH) was prepared from 4 plant extracts including Phyllostachis Bambusoides, Sophora Flavescens Root, Lycium Barbarum Fruit and Pyracantha Fortuneana Fruit through ethanol extraction, filtration and concentration. Focus on tyrosinase activity and melanin content, mH repressed the activity of tyrosinase from mushroom and B16F1 cells to 49.2% and 76.2% respectively, at concentration of 3%. mH reduced the cellular melanin synthesis to 98.2% in nature and 92.1% under α-MSH induced melanogenesis respectively, showed a dose-dependently inhibitory effect. The human-skin test results showed that the skin melanin content (MI value) was significantly reduced by 12.3% after 7 weeks application of a cream containing 5% mH, better than arbutin of 2% concentration. All the results indicate that mH displays a good effect for whitening.

Published in	Science Discovery (Volume 6, Issue 4)
DOI	10.11648/j.sd.20180604.22
Page(s)	306-311
Creative Commons	This is an Open Access article, distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution and reproduction in any medium or format, provided the original work is properly cited.
Copyright	Copyright © The Author(s), 2024. Published by Science Publishing Group

Keywords

Multi-Herb, Tyrosinase, Melanin Synthesis, Human-Skin Test

References

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APA Style

Lu Yi-na, Yang Ya-di, Lin Meng-gan, Xie Zhi-yong. (2018). Whitening Efficacy Evaluation of the Multi-Herb. Science Discovery, 6(4), 306-311. https://doi.org/10.11648/j.sd.20180604.22

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ACS Style

Lu Yi-na; Yang Ya-di; Lin Meng-gan; Xie Zhi-yong. Whitening Efficacy Evaluation of the Multi-Herb. Sci. Discov. 2018, 6(4), 306-311. doi: 10.11648/j.sd.20180604.22

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AMA Style

Lu Yi-na, Yang Ya-di, Lin Meng-gan, Xie Zhi-yong. Whitening Efficacy Evaluation of the Multi-Herb. Sci Discov. 2018;6(4):306-311. doi: 10.11648/j.sd.20180604.22

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@article{10.11648/j.sd.20180604.22,
  author = {Lu Yi-na and Yang Ya-di and Lin Meng-gan and Xie Zhi-yong},
  title = {Whitening Efficacy Evaluation of the Multi-Herb},
  journal = {Science Discovery},
  volume = {6},
  number = {4},
  pages = {306-311},
  doi = {10.11648/j.sd.20180604.22},
  url = {https://doi.org/10.11648/j.sd.20180604.22},
  eprint = {https://article.sciencepublishinggroup.com/pdf/10.11648.j.sd.20180604.22},
  abstract = {The multi-Herb (mH) was prepared from 4 plant extracts including Phyllostachis Bambusoides, Sophora Flavescens Root, Lycium Barbarum Fruit and Pyracantha Fortuneana Fruit through ethanol extraction, filtration and concentration. Focus on tyrosinase activity and melanin content, mH repressed the activity of tyrosinase from mushroom and B16F1 cells to 49.2% and 76.2% respectively, at concentration of 3%. mH reduced the cellular melanin synthesis to 98.2% in nature and 92.1% under α-MSH induced melanogenesis respectively, showed a dose-dependently inhibitory effect. The human-skin test results showed that the skin melanin content (MI value) was significantly reduced by 12.3% after 7 weeks application of a cream containing 5% mH, better than arbutin of 2% concentration. All the results indicate that mH displays a good effect for whitening.},
 year = {2018}
}

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TY  - JOUR
T1  - Whitening Efficacy Evaluation of the Multi-Herb
AU  - Lu Yi-na
AU  - Yang Ya-di
AU  - Lin Meng-gan
AU  - Xie Zhi-yong
Y1  - 2018/08/10
PY  - 2018
N1  - https://doi.org/10.11648/j.sd.20180604.22
DO  - 10.11648/j.sd.20180604.22
T2  - Science Discovery
JF  - Science Discovery
JO  - Science Discovery
SP  - 306
EP  - 311
PB  - Science Publishing Group
SN  - 2331-0650
UR  - https://doi.org/10.11648/j.sd.20180604.22
AB  - The multi-Herb (mH) was prepared from 4 plant extracts including Phyllostachis Bambusoides, Sophora Flavescens Root, Lycium Barbarum Fruit and Pyracantha Fortuneana Fruit through ethanol extraction, filtration and concentration. Focus on tyrosinase activity and melanin content, mH repressed the activity of tyrosinase from mushroom and B16F1 cells to 49.2% and 76.2% respectively, at concentration of 3%. mH reduced the cellular melanin synthesis to 98.2% in nature and 92.1% under α-MSH induced melanogenesis respectively, showed a dose-dependently inhibitory effect. The human-skin test results showed that the skin melanin content (MI value) was significantly reduced by 12.3% after 7 weeks application of a cream containing 5% mH, better than arbutin of 2% concentration. All the results indicate that mH displays a good effect for whitening.
VL  - 6
IS  - 4
ER  -

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Author Information

Lu Yi-na

Shanghai Greaf Biotech Co. Ltd., Shanghai, China
Yang Ya-di

Shanghai Greaf Biotech Co. Ltd., Shanghai, China
Lin Meng-gan

Shanghai Greaf Biotech Co. Ltd., Shanghai, China
Xie Zhi-yong

Shanghai Greaf Biotech Co. Ltd., Shanghai, China

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Plain Text BibTeX RIS

APA Style

Lu Yi-na, Yang Ya-di, Lin Meng-gan, Xie Zhi-yong. (2018). Whitening Efficacy Evaluation of the Multi-Herb. Science Discovery, 6(4), 306-311. https://doi.org/10.11648/j.sd.20180604.22

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ACS Style

Lu Yi-na; Yang Ya-di; Lin Meng-gan; Xie Zhi-yong. Whitening Efficacy Evaluation of the Multi-Herb. Sci. Discov. 2018, 6(4), 306-311. doi: 10.11648/j.sd.20180604.22

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AMA Style

Lu Yi-na, Yang Ya-di, Lin Meng-gan, Xie Zhi-yong. Whitening Efficacy Evaluation of the Multi-Herb. Sci Discov. 2018;6(4):306-311. doi: 10.11648/j.sd.20180604.22

Copy | Download

@article{10.11648/j.sd.20180604.22,
  author = {Lu Yi-na and Yang Ya-di and Lin Meng-gan and Xie Zhi-yong},
  title = {Whitening Efficacy Evaluation of the Multi-Herb},
  journal = {Science Discovery},
  volume = {6},
  number = {4},
  pages = {306-311},
  doi = {10.11648/j.sd.20180604.22},
  url = {https://doi.org/10.11648/j.sd.20180604.22},
  eprint = {https://article.sciencepublishinggroup.com/pdf/10.11648.j.sd.20180604.22},
  abstract = {The multi-Herb (mH) was prepared from 4 plant extracts including Phyllostachis Bambusoides, Sophora Flavescens Root, Lycium Barbarum Fruit and Pyracantha Fortuneana Fruit through ethanol extraction, filtration and concentration. Focus on tyrosinase activity and melanin content, mH repressed the activity of tyrosinase from mushroom and B16F1 cells to 49.2% and 76.2% respectively, at concentration of 3%. mH reduced the cellular melanin synthesis to 98.2% in nature and 92.1% under α-MSH induced melanogenesis respectively, showed a dose-dependently inhibitory effect. The human-skin test results showed that the skin melanin content (MI value) was significantly reduced by 12.3% after 7 weeks application of a cream containing 5% mH, better than arbutin of 2% concentration. All the results indicate that mH displays a good effect for whitening.},
 year = {2018}
}

Copy | Download

TY  - JOUR
T1  - Whitening Efficacy Evaluation of the Multi-Herb
AU  - Lu Yi-na
AU  - Yang Ya-di
AU  - Lin Meng-gan
AU  - Xie Zhi-yong
Y1  - 2018/08/10
PY  - 2018
N1  - https://doi.org/10.11648/j.sd.20180604.22
DO  - 10.11648/j.sd.20180604.22
T2  - Science Discovery
JF  - Science Discovery
JO  - Science Discovery
SP  - 306
EP  - 311
PB  - Science Publishing Group
SN  - 2331-0650
UR  - https://doi.org/10.11648/j.sd.20180604.22
AB  - The multi-Herb (mH) was prepared from 4 plant extracts including Phyllostachis Bambusoides, Sophora Flavescens Root, Lycium Barbarum Fruit and Pyracantha Fortuneana Fruit through ethanol extraction, filtration and concentration. Focus on tyrosinase activity and melanin content, mH repressed the activity of tyrosinase from mushroom and B16F1 cells to 49.2% and 76.2% respectively, at concentration of 3%. mH reduced the cellular melanin synthesis to 98.2% in nature and 92.1% under α-MSH induced melanogenesis respectively, showed a dose-dependently inhibitory effect. The human-skin test results showed that the skin melanin content (MI value) was significantly reduced by 12.3% after 7 weeks application of a cream containing 5% mH, better than arbutin of 2% concentration. All the results indicate that mH displays a good effect for whitening.
VL  - 6
IS  - 4
ER  -

Copy | Download