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PFOS and ZnO Nanoparticles Induced Oxidative Stress in Liver, Gill and Head of Zebrafish

Received: 19 July 2016    Accepted:     Published: 20 July 2016
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Abstract

Oxidative stress to liver, gill and head of zebrafish (Danio rerio) induced by perfluorooctanesul phonic acid potassium salt (PFOS) and ZnO nanoparticles (Nano-ZnO) is investigated in this study. Activities of superoxide dismutase (SOD), catalase (CAT) and malondialdehyde (MDA) contents were measured in liver, gill and head of zebrafish. The results demonstrated that both PFOS and Nano-ZnO single and co-exposure induced oxidative stress. In addition, PFOS plus Nano-ZnO exposure caused more serious oxidative stress than single-exposure at above exposure concentrations. Besides, compare with single-exposure, the activity of CAT is significantly lower, while the content of MDA is significantly higher in co-exposure solutions. The biochemical assays of head showed that, compare with single-exposure, co-exposure had more obvious effect on the activities of SOD, CAT and the content of MDA. Under the toxicity ratio of 1:1, Nano-ZnO increased the toxicity of PFOS on oxidative stress in liver, gill and head of zebrafish at the experimental concentrations.

DOI 10.11648/j.sd.20160404.15
Published in Science Discovery (Volume 4, Issue 4, August 2016)
Page(s) 232-237
Creative Commons

This is an Open Access article, distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution and reproduction in any medium or format, provided the original work is properly cited.

Copyright

Copyright © The Author(s), 2024. Published by Science Publishing Group

Keywords

Perfluorooctanesul Phonic Acid Potassium Salt (PFOS), ZnO Nanoparticles (Nano-ZnO), Oxidative Stress, Joint Toxicity

References
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Author Information
  • State Key Laboratory of Urban Water Resource and Environment, Harbin Institute of Technology, Harbin, China

  • State Key Laboratory of Urban Water Resource and Environment, Harbin Institute of Technology, Harbin, China

  • State Key Laboratory of Urban Water Resource and Environment, Harbin Institute of Technology, Harbin, China

  • School of Marine Science and Technology, Harbin Institute of Technology at Weihai, Harbin, China

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    Liu Zheng, Du Jia, Wang Shutao, You Hong. (2016). PFOS and ZnO Nanoparticles Induced Oxidative Stress in Liver, Gill and Head of Zebrafish. Science Discovery, 4(4), 232-237. https://doi.org/10.11648/j.sd.20160404.15

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    ACS Style

    Liu Zheng; Du Jia; Wang Shutao; You Hong. PFOS and ZnO Nanoparticles Induced Oxidative Stress in Liver, Gill and Head of Zebrafish. Sci. Discov. 2016, 4(4), 232-237. doi: 10.11648/j.sd.20160404.15

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    AMA Style

    Liu Zheng, Du Jia, Wang Shutao, You Hong. PFOS and ZnO Nanoparticles Induced Oxidative Stress in Liver, Gill and Head of Zebrafish. Sci Discov. 2016;4(4):232-237. doi: 10.11648/j.sd.20160404.15

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  • @article{10.11648/j.sd.20160404.15,
      author = {Liu Zheng and Du Jia and Wang Shutao and You Hong},
      title = {PFOS and ZnO Nanoparticles Induced Oxidative Stress in Liver, Gill and Head of Zebrafish},
      journal = {Science Discovery},
      volume = {4},
      number = {4},
      pages = {232-237},
      doi = {10.11648/j.sd.20160404.15},
      url = {https://doi.org/10.11648/j.sd.20160404.15},
      eprint = {https://download.sciencepg.com/pdf/10.11648.j.sd.20160404.15},
      abstract = {Oxidative stress to liver, gill and head of zebrafish (Danio rerio) induced by perfluorooctanesul phonic acid potassium salt (PFOS) and ZnO nanoparticles (Nano-ZnO) is investigated in this study. Activities of superoxide dismutase (SOD), catalase (CAT) and malondialdehyde (MDA) contents were measured in liver, gill and head of zebrafish. The results demonstrated that both PFOS and Nano-ZnO single and co-exposure induced oxidative stress. In addition, PFOS plus Nano-ZnO exposure caused more serious oxidative stress than single-exposure at above exposure concentrations. Besides, compare with single-exposure, the activity of CAT is significantly lower, while the content of MDA is significantly higher in co-exposure solutions. The biochemical assays of head showed that, compare with single-exposure, co-exposure had more obvious effect on the activities of SOD, CAT and the content of MDA. Under the toxicity ratio of 1:1, Nano-ZnO increased the toxicity of PFOS on oxidative stress in liver, gill and head of zebrafish at the experimental concentrations.},
     year = {2016}
    }
    

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  • TY  - JOUR
    T1  - PFOS and ZnO Nanoparticles Induced Oxidative Stress in Liver, Gill and Head of Zebrafish
    AU  - Liu Zheng
    AU  - Du Jia
    AU  - Wang Shutao
    AU  - You Hong
    Y1  - 2016/07/20
    PY  - 2016
    N1  - https://doi.org/10.11648/j.sd.20160404.15
    DO  - 10.11648/j.sd.20160404.15
    T2  - Science Discovery
    JF  - Science Discovery
    JO  - Science Discovery
    SP  - 232
    EP  - 237
    PB  - Science Publishing Group
    SN  - 2331-0650
    UR  - https://doi.org/10.11648/j.sd.20160404.15
    AB  - Oxidative stress to liver, gill and head of zebrafish (Danio rerio) induced by perfluorooctanesul phonic acid potassium salt (PFOS) and ZnO nanoparticles (Nano-ZnO) is investigated in this study. Activities of superoxide dismutase (SOD), catalase (CAT) and malondialdehyde (MDA) contents were measured in liver, gill and head of zebrafish. The results demonstrated that both PFOS and Nano-ZnO single and co-exposure induced oxidative stress. In addition, PFOS plus Nano-ZnO exposure caused more serious oxidative stress than single-exposure at above exposure concentrations. Besides, compare with single-exposure, the activity of CAT is significantly lower, while the content of MDA is significantly higher in co-exposure solutions. The biochemical assays of head showed that, compare with single-exposure, co-exposure had more obvious effect on the activities of SOD, CAT and the content of MDA. Under the toxicity ratio of 1:1, Nano-ZnO increased the toxicity of PFOS on oxidative stress in liver, gill and head of zebrafish at the experimental concentrations.
    VL  - 4
    IS  - 4
    ER  - 

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