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Study on the Bactericidal Effect of Ortho-Phthalaldehyde Combination Disinfectant

Received: 27 December 2017    Accepted:     Published: 28 December 2017
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Abstract

This study used combination of ortho-phthalaldehyde(OPA) and quaternary ammonium surfactants (QAS) with different concentration to kill Escherichia coli, Staphylococcus aureus, Candida albicans and Aspergillus niger conidia. The concentration of the combination disinfectant to kill Escherichia coli, Staphylococcus aureus and Candida albicans was 75mg/L OPA and 30mg/L QAS within 10 min, respectively. The average killing log value was above 4 when Aspergillus niger conidia was exposed in 3.75g/L OPA and 1.50g/L QAS for one hour. Then the effects of time, temperature and organic concentration on the bactericidal effect were measured. And the metal corrosion and stability of the combination disinfectant were determined. In addition, these results showed that the combination disinfectant had a high efficiency of bacteria killing and the concentration of organic affected its bactericidal effect. The average killing log value gradually increased along with the temperature within 10°C. to 40°C. And the combination disinfectant also has the advantages of low corrosive of metal, good stability and so on.

DOI 10.11648/j.sd.20170506.25
Published in Science Discovery (Volume 5, Issue 6, November 2017)
Page(s) 479-485
Creative Commons

This is an Open Access article, distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution and reproduction in any medium or format, provided the original work is properly cited.

Copyright

Copyright © The Author(s), 2024. Published by Science Publishing Group

Keywords

Ortho-Phthalaldehyde, Escherichia coli, Metal Corrosive, Quaternary Ammonium Surfactants

References
[1] Russell AD. Introduction of biocides into clinical practice and the impact on antibiotic‐resistant bacteria [J]. Journal of Applied Microbiology 2002; 92(31): 121S-135S.
[2] Martínezcamacho AP, Cortezrocha MO, Ezquerrabrauer JM, et al. Chitosan composite films: thermal, structural, mechanical and antifungal properties [J]. Carbohydrate Polymers 2010; 82: 305-15.
[3] Rutala WA, Weber DJ. New disinfection and sterilization methods [J]. Emerging Infectious Diseases 2001;7:348.
[4] 常文军,蔡全才,徐荷等.邻苯二甲醛消毒剂研究进展[J].中国消毒学杂志,2004;21:67-9。
[5] 李崇珍.内窥镜灭菌技术进展[J].护理研究,2004;18:1799-801。
[6] 韩菲.复方邻苯二甲醛纳米乳的研制[D]:西北农林科技大学;2009。
[7] 梁克中.水处理剂简介[J].山东化工,2004:37-9。
[8] 汪坤,海洪,金文英等.微波辅助提取蚕沙中叶绿素的工艺研究[J].食品科学,2009;30:76-9。
[9] 薛文青.季铵盐类阳离子表面活性消毒剂研究进展[J].中华医院感染学杂志,2002,12(8):79-81。
[10] Lin W, Xiao G, Jing C, et al. Bactericidal mechanism of glutaraldehyde-didecyldimethylammonium bromide as a disinfectant against Escherichia coli [J]. Journal of Applied Microbiology 2017;122:676-85.
[11] 李小林,关潇,林文淑等.新型戊二醛-癸甲溴铵复合消毒剂的杀菌效果及其影响因素的研究[J].中国国境卫生检疫杂志,2017(4):283-289。
[12] 卫生部卫生法制与监督司.消毒技术规范[S].北京:卫生部,2008:135-137。
[13] 梁建生.季铵盐类消毒剂及其应用[J].中国消毒学杂志,2012, 29(2):129-131。
[14] Namba Y, Suzuki A, Takeshima N, et al. Comparative study of bactericidal activities of six different disinfectants [J]. Nagoya Journal of Medical Science, 1985, 47(3-4):101.
[15] 沈伟,孙玉卿,谢星辉等.戊二醛增效剂探索[J].现代预防医学,1997:262-4。
[16] 房军,姚楚水.戊二醛消毒液杀菌效果及其影响因素的实验研究[J].中国消毒学杂志,2007;24:321-4。
[17] 王长德,张文福,芦懿等.邻苯二甲醛杀菌效果影响因素的研究[J].中国消毒学杂志,2004;21:182-5。
[18] Bolton N F, Cromar N J, Hallsworth P, et al. A review of the factors affecting sunlight inactivation of micro-organisms in waste stabilisation ponds: preliminary results for enterococci [J]. Water Science & Technology A Journal of the International Association on Water Pollution Research, 2010, 61(4):885-90.
[19] Kollu K, Ormeci B. Effect of particles and bioflocculation on ultraviolet disinfection of Escherichia coli [J]. Water Research, 2012, 46(3):750-60.
[20] Nicholas R, Dunton P, Tatham A, et al. The effect of ozone and open air factor on surface-attached and biofilm environmental Listeria monocytogenes [J]. Journal of Applied Microbiology, 2013, 115(2):555-64.
Author Information
  • School of Life Sciences, Shanghai University, Shanghai, China

  • School of Life Sciences, Shanghai University, Shanghai, China

  • School of Life Sciences, Shanghai University, Shanghai, China

  • School of Life Sciences, Shanghai University, Shanghai, China

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    Yi Jialin, Niu Bing, Deng Zhirui, Chen Qin. (2017). Study on the Bactericidal Effect of Ortho-Phthalaldehyde Combination Disinfectant. Science Discovery, 5(6), 479-485. https://doi.org/10.11648/j.sd.20170506.25

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    ACS Style

    Yi Jialin; Niu Bing; Deng Zhirui; Chen Qin. Study on the Bactericidal Effect of Ortho-Phthalaldehyde Combination Disinfectant. Sci. Discov. 2017, 5(6), 479-485. doi: 10.11648/j.sd.20170506.25

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    AMA Style

    Yi Jialin, Niu Bing, Deng Zhirui, Chen Qin. Study on the Bactericidal Effect of Ortho-Phthalaldehyde Combination Disinfectant. Sci Discov. 2017;5(6):479-485. doi: 10.11648/j.sd.20170506.25

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  • @article{10.11648/j.sd.20170506.25,
      author = {Yi Jialin and Niu Bing and Deng Zhirui and Chen Qin},
      title = {Study on the Bactericidal Effect of Ortho-Phthalaldehyde Combination Disinfectant},
      journal = {Science Discovery},
      volume = {5},
      number = {6},
      pages = {479-485},
      doi = {10.11648/j.sd.20170506.25},
      url = {https://doi.org/10.11648/j.sd.20170506.25},
      eprint = {https://download.sciencepg.com/pdf/10.11648.j.sd.20170506.25},
      abstract = {This study used combination of ortho-phthalaldehyde(OPA) and quaternary ammonium surfactants (QAS) with different concentration to kill Escherichia coli, Staphylococcus aureus, Candida albicans and Aspergillus niger conidia. The concentration of the combination disinfectant to kill Escherichia coli, Staphylococcus aureus and Candida albicans was 75mg/L OPA and 30mg/L QAS within 10 min, respectively. The average killing log value was above 4 when Aspergillus niger conidia was exposed in 3.75g/L OPA and 1.50g/L QAS for one hour. Then the effects of time, temperature and organic concentration on the bactericidal effect were measured. And the metal corrosion and stability of the combination disinfectant were determined. In addition, these results showed that the combination disinfectant had a high efficiency of bacteria killing and the concentration of organic affected its bactericidal effect. The average killing log value gradually increased along with the temperature within 10°C. to 40°C. And the combination disinfectant also has the advantages of low corrosive of metal, good stability and so on.},
     year = {2017}
    }
    

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  • TY  - JOUR
    T1  - Study on the Bactericidal Effect of Ortho-Phthalaldehyde Combination Disinfectant
    AU  - Yi Jialin
    AU  - Niu Bing
    AU  - Deng Zhirui
    AU  - Chen Qin
    Y1  - 2017/12/28
    PY  - 2017
    N1  - https://doi.org/10.11648/j.sd.20170506.25
    DO  - 10.11648/j.sd.20170506.25
    T2  - Science Discovery
    JF  - Science Discovery
    JO  - Science Discovery
    SP  - 479
    EP  - 485
    PB  - Science Publishing Group
    SN  - 2331-0650
    UR  - https://doi.org/10.11648/j.sd.20170506.25
    AB  - This study used combination of ortho-phthalaldehyde(OPA) and quaternary ammonium surfactants (QAS) with different concentration to kill Escherichia coli, Staphylococcus aureus, Candida albicans and Aspergillus niger conidia. The concentration of the combination disinfectant to kill Escherichia coli, Staphylococcus aureus and Candida albicans was 75mg/L OPA and 30mg/L QAS within 10 min, respectively. The average killing log value was above 4 when Aspergillus niger conidia was exposed in 3.75g/L OPA and 1.50g/L QAS for one hour. Then the effects of time, temperature and organic concentration on the bactericidal effect were measured. And the metal corrosion and stability of the combination disinfectant were determined. In addition, these results showed that the combination disinfectant had a high efficiency of bacteria killing and the concentration of organic affected its bactericidal effect. The average killing log value gradually increased along with the temperature within 10°C. to 40°C. And the combination disinfectant also has the advantages of low corrosive of metal, good stability and so on.
    VL  - 5
    IS  - 6
    ER  - 

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