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Synthesis and Spectroscopic Analysis of the Nature of Coordination Modes of Ligands in Copper (ll) and Cadmium (ll) Complexes of Two N-Oxidobenzamide Derivatives
International Journal of Science, Technology and Society
Volume 5, Issue 5, September 2017, Pages: 179-181
Received: Aug. 17, 2017; Accepted: Aug. 25, 2017; Published: Sep. 19, 2017
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Saranya Sathiyavasan, Department of Human Biology, Faculty of Health-Care Sciences, Eastern University of Sri Lanka, Batticaloa, Sri Lanka
Maheswaran Sithambaresan, Department of Chemistry, Faculty of Science, Eastern University of Sri Lanka, Batticaloa, Sri Lanka
Parthiban Gunasingham, Department of Chemistry, Faculty of Science, Eastern University of Sri Lanka, Batticaloa, Sri Lanka
Ratnasothy Srikaran, Department of Chemistry, Faculty of Science, University of Jaffna, Jaffna, Sri Lanka
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N-Oxidobenzamide derivatives are powerful metal ion chelators. It is used as inhibitors of hypertension, tumor growth, inflammation, infectious agents, asthma, arthritis, Alzheimer’s diseases and more. In this study, Copper (ll) (SRC1 and SRC3) and Cadmium (ll) (SRC2 and SRC4) complexes were synthesized from potassium N-Oxidobenzamide derivative ligands and they were characterized by using various techniques such as Infra-Red spectra, electronic spectra, melting point and conductivity measurements. The electronic spectral study and the melting point analysis revealed that the ligands are coordinated to the metal centre. IR and conductivity analyses confirm the coordination of hydroxamate ions to the metal centre as O, O-bidentate mode via the hydroxyl oxygen and the carbonyl oxygen atoms of the ligands. The proposed molecular structures for the newly formed complexes are also given.
Hydroxamic Acids, N-Oxidobenzamide, Copper(ll) Complex, Cadmium (ll) Complex and Analytical Techniques
To cite this article
Saranya Sathiyavasan, Maheswaran Sithambaresan, Parthiban Gunasingham, Ratnasothy Srikaran, Synthesis and Spectroscopic Analysis of the Nature of Coordination Modes of Ligands in Copper (ll) and Cadmium (ll) Complexes of Two N-Oxidobenzamide Derivatives, International Journal of Science, Technology and Society. Vol. 5, No. 5, 2017, pp. 179-181. doi: 10.11648/j.ijsts.20170505.16
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Rittakakkar, Theoretical studies on Hydroxamic Acids, Springer –Verlag Berlin Heideberg, (2013), P: 19-53.
Naqeebullah, Yang Farina, KokMeng Chan, Lo Kong Mun Nor Fadilah Rajab and Theng Choon Ooi, Diorganotin (IV) Derivatives of N-Methyl p-Fluorobenzo-Hydroxamic Acid: Preparation, Spectral Characterization, X-ray Diffraction Studies and Antitumor Activity, Molecules (2013), 18, P: 8696-8711.
Farkas, E., Csoka, H., Gama, S., Santos, M. A. Dihydroxamate based siderophore model, piperazine-1,4-bis-(N-methyl-acetohydroxamic acid (PIPDMAHA), as a chelating agent of molybdenum(VI). Talanta (2002), 57, 935–943.
Munster, P. N.; Troso-Sandoval, T.; Rosen, N.; Rifkind, R.; Marks, P. A.; Richon, V. M. The histone deacetylase inhibitor suberoylanilide hydroxamic acid induces differentiation of human breast cancer cells. Cancer Res. (2001), 61, 8492–8497.
Codd. R, Traversing the coordination chemistry and chemical biology of hydroxamic acid, Coord. Chem, Rev.(2008), 252, P: 1387–1408.
S. Sasi, M. Sithambaresan, MRP Kurup, HK Fun, Syntheses, EPR spectral studies and crystal structures of manganese (II) complexes of neutral N, N donor bidentate Schiff bases and azide/thiocyanate as coligand, Polyhedron (2010), 29, p: 2643-2650.
Pavia, Lampman, Kriz, Vyvyan, Intoduction to Spectroscopy, Fourth Edition, Brooks/Cole Cengage Learning, (2007), P: 15-89, 381-413.
Jain, R.; Sundram, A.; Lopez, S.; Neckermann, G.; Wu, C.; Hackbarth, C.; Chen, D.; Wang, W.; Ryder, NS.; Weidmann, B.; et al. α-Substituted hydroxamic acids as novel bacterial deformylase inhibitor-based antibacterial agents. Bioorg. Med. Chem. Lett. (2003), 13, 4223–4228.
Petrosyan, V. S.; Yashina, N. S.; Ponomarev, S. V. Syntheses, Structures and biological activites of Organogermaniun and Organotin derivatives of hydroxamic acids. Met. Based Drugs (1998), 5, 237–244.
Baul, T.; Masharing, C.; Ruisi, G.; Jirasko, R.; Holcapek, M.; De Vos, D.; Wolstenholme, D.; Linden, A. Self-assembly of extended Schiff base amino acetate keletons, 2-{[(2Z)-(3-hydroxy-1-Methyl-2-butenylidene)]amino}Phenylpropio-nate and 2-{[(E)-1-(2-hydroxy-aryl) alkylidene] amino} Phenyl-propionate skeletons incorporating organotin(IV) moieties: Synthesis, spectroscopic characterization, crystal structures, and in vitro cytotoxic activity. J. Organomet. Chem. (2007), 692, 4849–4862.
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