Evaluation of Growth Performance, IL-6 and Serum Biochemical Parameters of Rats Fed on Diets Containing Thyme and Ginger Powder

Sabry Abd El-Gawad Abd El-Halim El-Sayed; Sarah Yousef Abd El-Galil Ahmed

doi:doi:10.11648/j.avs.20160405.12

| Peer-Reviewed

Evaluation of Growth Performance, IL-6 and Serum Biochemical Parameters of Rats Fed on Diets Containing Thyme and Ginger Powder

Sabry Abd El-Gawad Abd El-Halim El-Sayed, Sarah Yousef Abd El-Galil Ahmed

Published in Animal and Veterinary Sciences (Volume 4, Issue 5)

Received: 26 September 2016 Accepted: 7 October 2016 Published: 31 October 2016

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Abstract

Antibiotics have been extensively used as feed additives and growth performance in animal feed industry. The use of antibiotics is hazardous due to multiple resistances of pathogens. Thyme and ginger are medicinal herbs which have anti-inflammatory, antimicrobial, and antioxidant properties and used as feed additives in animal industry. Thus, the present study carried out to estimate the effect of thyme and ginger on some biochemical and immunological parameters in addition to their effect on the growth performance. Fifteen male rats were divided into three groups, first one was fed on basal diet (the control), second group was fed on basal diet contained thyme (5%) and the third was fed on basal diet contained ginger (5%). The experiment lasts for 4 weeks and then serum sample was collected. Our results revealed the presence of significantly increase in body weight; body gain and feed efficiency values in treated groups in comparison with the control group. Total globulins and alkaline phosphatase (ALP) were significantly increased for ginger and thyme groups in comparing with control group meanwhile total proteins and albumin recorded non-significant change, GOT increased in ginger group but not in thyme one. Thyme and ginger decreased triglyceride (TG), total cholesterol (TC) and low density lipoproteins (LDL) even though high density lipoproteins (HDL) showed no significant change in either group. Thyme decreased serum urea and Creatinine meanwhile ginger increased serum Creatinine with no significant change of urea. On the other hand Thyme significantly decreases production of serum Interleukin 6 (IL-6) in mice while ginger increased its level in serum. The present study concluded that either thyme or ginger have positive effect on some biochemical and immunological parameters in addition to their effect on growth performance however they have negative effect on others, as this is the first recorded increase of ALP with the two herbs so the using of the herbs must under restriction.

Published in	Animal and Veterinary Sciences (Volume 4, Issue 5)
DOI	10.11648/j.avs.20160405.12
Page(s)	78-85
Creative Commons	This is an Open Access article, distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution and reproduction in any medium or format, provided the original work is properly cited.
Copyright	Copyright © The Author(s), 2024. Published by Science Publishing Group

Keywords

Thyme Powder, Ginger Powder, Growth Performance, Biochemical Parameter, Interleukin 6, Rats

References

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Sabry Abd El-Gawad Abd El-Halim El-Sayed, Sarah Yousef Abd El-Galil Ahmed. (2016). Evaluation of Growth Performance, IL-6 and Serum Biochemical Parameters of Rats Fed on Diets Containing Thyme and Ginger Powder. Animal and Veterinary Sciences, 4(5), 78-85. https://doi.org/10.11648/j.avs.20160405.12

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Sabry Abd El-Gawad Abd El-Halim El-Sayed; Sarah Yousef Abd El-Galil Ahmed. Evaluation of Growth Performance, IL-6 and Serum Biochemical Parameters of Rats Fed on Diets Containing Thyme and Ginger Powder. Anim. Vet. Sci. 2016, 4(5), 78-85. doi: 10.11648/j.avs.20160405.12

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Sabry Abd El-Gawad Abd El-Halim El-Sayed, Sarah Yousef Abd El-Galil Ahmed. Evaluation of Growth Performance, IL-6 and Serum Biochemical Parameters of Rats Fed on Diets Containing Thyme and Ginger Powder. Anim Vet Sci. 2016;4(5):78-85. doi: 10.11648/j.avs.20160405.12

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@article{10.11648/j.avs.20160405.12,
  author = {Sabry Abd El-Gawad Abd El-Halim El-Sayed and Sarah Yousef Abd El-Galil Ahmed},
  title = {Evaluation of Growth Performance, IL-6 and Serum Biochemical Parameters of Rats Fed on Diets Containing Thyme and Ginger Powder},
  journal = {Animal and Veterinary Sciences},
  volume = {4},
  number = {5},
  pages = {78-85},
  doi = {10.11648/j.avs.20160405.12},
  url = {https://doi.org/10.11648/j.avs.20160405.12},
  eprint = {https://article.sciencepublishinggroup.com/pdf/10.11648.j.avs.20160405.12},
  abstract = {Antibiotics have been extensively used as feed additives and growth performance in animal feed industry. The use of antibiotics is hazardous due to multiple resistances of pathogens. Thyme and ginger are medicinal herbs which have anti-inflammatory, antimicrobial, and antioxidant properties and used as feed additives in animal industry. Thus, the present study carried out to estimate the effect of thyme and ginger on some biochemical and immunological parameters in addition to their effect on the growth performance. Fifteen male rats were divided into three groups, first one was fed on basal diet (the control), second group was fed on basal diet contained thyme (5%) and the third was fed on basal diet contained ginger (5%). The experiment lasts for 4 weeks and then serum sample was collected. Our results revealed the presence of significantly increase in body weight; body gain and feed efficiency values in treated groups in comparison with the control group. Total globulins and alkaline phosphatase (ALP) were significantly increased for ginger and thyme groups in comparing with control group meanwhile total proteins and albumin recorded non-significant change, GOT increased in ginger group but not in thyme one. Thyme and ginger decreased triglyceride (TG), total cholesterol (TC) and low density lipoproteins (LDL) even though high density lipoproteins (HDL) showed no significant change in either group. Thyme decreased serum urea and Creatinine meanwhile ginger increased serum Creatinine with no significant change of urea. On the other hand Thyme significantly decreases production of serum Interleukin 6 (IL-6) in mice while ginger increased its level in serum. The present study concluded that either thyme or ginger have positive effect on some biochemical and immunological parameters in addition to their effect on growth performance however they have negative effect on others, as this is the first recorded increase of ALP with the two herbs so the using of the herbs must under restriction.},
 year = {2016}
}

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TY  - JOUR
T1  - Evaluation of Growth Performance, IL-6 and Serum Biochemical Parameters of Rats Fed on Diets Containing Thyme and Ginger Powder
AU  - Sabry Abd El-Gawad Abd El-Halim El-Sayed
AU  - Sarah Yousef Abd El-Galil Ahmed
Y1  - 2016/10/31
PY  - 2016
N1  - https://doi.org/10.11648/j.avs.20160405.12
DO  - 10.11648/j.avs.20160405.12
T2  - Animal and Veterinary Sciences
JF  - Animal and Veterinary Sciences
JO  - Animal and Veterinary Sciences
SP  - 78
EP  - 85
PB  - Science Publishing Group
SN  - 2328-5850
UR  - https://doi.org/10.11648/j.avs.20160405.12
AB  - Antibiotics have been extensively used as feed additives and growth performance in animal feed industry. The use of antibiotics is hazardous due to multiple resistances of pathogens. Thyme and ginger are medicinal herbs which have anti-inflammatory, antimicrobial, and antioxidant properties and used as feed additives in animal industry. Thus, the present study carried out to estimate the effect of thyme and ginger on some biochemical and immunological parameters in addition to their effect on the growth performance. Fifteen male rats were divided into three groups, first one was fed on basal diet (the control), second group was fed on basal diet contained thyme (5%) and the third was fed on basal diet contained ginger (5%). The experiment lasts for 4 weeks and then serum sample was collected. Our results revealed the presence of significantly increase in body weight; body gain and feed efficiency values in treated groups in comparison with the control group. Total globulins and alkaline phosphatase (ALP) were significantly increased for ginger and thyme groups in comparing with control group meanwhile total proteins and albumin recorded non-significant change, GOT increased in ginger group but not in thyme one. Thyme and ginger decreased triglyceride (TG), total cholesterol (TC) and low density lipoproteins (LDL) even though high density lipoproteins (HDL) showed no significant change in either group. Thyme decreased serum urea and Creatinine meanwhile ginger increased serum Creatinine with no significant change of urea. On the other hand Thyme significantly decreases production of serum Interleukin 6 (IL-6) in mice while ginger increased its level in serum. The present study concluded that either thyme or ginger have positive effect on some biochemical and immunological parameters in addition to their effect on growth performance however they have negative effect on others, as this is the first recorded increase of ALP with the two herbs so the using of the herbs must under restriction.
VL  - 4
IS  - 5
ER  -

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Sabry Abd El-Gawad Abd El-Halim El-Sayed

Department of Nutrition and Clinical Nutrition, Faculty of Veterinary Medicine, Zagazig University, Zagazig, Egypt
Sarah Yousef Abd El-Galil Ahmed

Microbiology Department, Faculty of Veterinary Medicine, Zagazig University, Zagazig, Egypt; Department of Clinical Laboratory Sciences, College of Applied Medical Science, University of Hail, Hail, Saudi Arabia

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Sabry Abd El-Gawad Abd El-Halim El-Sayed, Sarah Yousef Abd El-Galil Ahmed. (2016). Evaluation of Growth Performance, IL-6 and Serum Biochemical Parameters of Rats Fed on Diets Containing Thyme and Ginger Powder. Animal and Veterinary Sciences, 4(5), 78-85. https://doi.org/10.11648/j.avs.20160405.12

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Sabry Abd El-Gawad Abd El-Halim El-Sayed; Sarah Yousef Abd El-Galil Ahmed. Evaluation of Growth Performance, IL-6 and Serum Biochemical Parameters of Rats Fed on Diets Containing Thyme and Ginger Powder. Anim. Vet. Sci. 2016, 4(5), 78-85. doi: 10.11648/j.avs.20160405.12

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AMA Style

Sabry Abd El-Gawad Abd El-Halim El-Sayed, Sarah Yousef Abd El-Galil Ahmed. Evaluation of Growth Performance, IL-6 and Serum Biochemical Parameters of Rats Fed on Diets Containing Thyme and Ginger Powder. Anim Vet Sci. 2016;4(5):78-85. doi: 10.11648/j.avs.20160405.12

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@article{10.11648/j.avs.20160405.12,
  author = {Sabry Abd El-Gawad Abd El-Halim El-Sayed and Sarah Yousef Abd El-Galil Ahmed},
  title = {Evaluation of Growth Performance, IL-6 and Serum Biochemical Parameters of Rats Fed on Diets Containing Thyme and Ginger Powder},
  journal = {Animal and Veterinary Sciences},
  volume = {4},
  number = {5},
  pages = {78-85},
  doi = {10.11648/j.avs.20160405.12},
  url = {https://doi.org/10.11648/j.avs.20160405.12},
  eprint = {https://article.sciencepublishinggroup.com/pdf/10.11648.j.avs.20160405.12},
  abstract = {Antibiotics have been extensively used as feed additives and growth performance in animal feed industry. The use of antibiotics is hazardous due to multiple resistances of pathogens. Thyme and ginger are medicinal herbs which have anti-inflammatory, antimicrobial, and antioxidant properties and used as feed additives in animal industry. Thus, the present study carried out to estimate the effect of thyme and ginger on some biochemical and immunological parameters in addition to their effect on the growth performance. Fifteen male rats were divided into three groups, first one was fed on basal diet (the control), second group was fed on basal diet contained thyme (5%) and the third was fed on basal diet contained ginger (5%). The experiment lasts for 4 weeks and then serum sample was collected. Our results revealed the presence of significantly increase in body weight; body gain and feed efficiency values in treated groups in comparison with the control group. Total globulins and alkaline phosphatase (ALP) were significantly increased for ginger and thyme groups in comparing with control group meanwhile total proteins and albumin recorded non-significant change, GOT increased in ginger group but not in thyme one. Thyme and ginger decreased triglyceride (TG), total cholesterol (TC) and low density lipoproteins (LDL) even though high density lipoproteins (HDL) showed no significant change in either group. Thyme decreased serum urea and Creatinine meanwhile ginger increased serum Creatinine with no significant change of urea. On the other hand Thyme significantly decreases production of serum Interleukin 6 (IL-6) in mice while ginger increased its level in serum. The present study concluded that either thyme or ginger have positive effect on some biochemical and immunological parameters in addition to their effect on growth performance however they have negative effect on others, as this is the first recorded increase of ALP with the two herbs so the using of the herbs must under restriction.},
 year = {2016}
}

Copy | Download

TY  - JOUR
T1  - Evaluation of Growth Performance, IL-6 and Serum Biochemical Parameters of Rats Fed on Diets Containing Thyme and Ginger Powder
AU  - Sabry Abd El-Gawad Abd El-Halim El-Sayed
AU  - Sarah Yousef Abd El-Galil Ahmed
Y1  - 2016/10/31
PY  - 2016
N1  - https://doi.org/10.11648/j.avs.20160405.12
DO  - 10.11648/j.avs.20160405.12
T2  - Animal and Veterinary Sciences
JF  - Animal and Veterinary Sciences
JO  - Animal and Veterinary Sciences
SP  - 78
EP  - 85
PB  - Science Publishing Group
SN  - 2328-5850
UR  - https://doi.org/10.11648/j.avs.20160405.12
AB  - Antibiotics have been extensively used as feed additives and growth performance in animal feed industry. The use of antibiotics is hazardous due to multiple resistances of pathogens. Thyme and ginger are medicinal herbs which have anti-inflammatory, antimicrobial, and antioxidant properties and used as feed additives in animal industry. Thus, the present study carried out to estimate the effect of thyme and ginger on some biochemical and immunological parameters in addition to their effect on the growth performance. Fifteen male rats were divided into three groups, first one was fed on basal diet (the control), second group was fed on basal diet contained thyme (5%) and the third was fed on basal diet contained ginger (5%). The experiment lasts for 4 weeks and then serum sample was collected. Our results revealed the presence of significantly increase in body weight; body gain and feed efficiency values in treated groups in comparison with the control group. Total globulins and alkaline phosphatase (ALP) were significantly increased for ginger and thyme groups in comparing with control group meanwhile total proteins and albumin recorded non-significant change, GOT increased in ginger group but not in thyme one. Thyme and ginger decreased triglyceride (TG), total cholesterol (TC) and low density lipoproteins (LDL) even though high density lipoproteins (HDL) showed no significant change in either group. Thyme decreased serum urea and Creatinine meanwhile ginger increased serum Creatinine with no significant change of urea. On the other hand Thyme significantly decreases production of serum Interleukin 6 (IL-6) in mice while ginger increased its level in serum. The present study concluded that either thyme or ginger have positive effect on some biochemical and immunological parameters in addition to their effect on growth performance however they have negative effect on others, as this is the first recorded increase of ALP with the two herbs so the using of the herbs must under restriction.
VL  - 4
IS  - 5
ER  -

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