American Journal of Bioscience and Bioengineering

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Phytochemical Screening and Anti-plasmodial Activity of Balsamodendron africanum (A. Rich) (Burseraceae)

Received: 19 September 2016    Accepted: 17 October 2016    Published: 16 January 2017
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Abstract

Balsamodendron africanum was popularly known to be present within tropical Africa and some Indian regions. The stem bark extract of the plant was investigated for phytochemical screening and In vitro anti-malarial bioassay using n-hexane, chloroform, ethylacetate and methanol solvent fractions. The phytochemical screening revealed the presence of flavonoids, alkaloids, terpenoids, tannins, saponins anthraquinones and carbohydrates. The bioassay results showed that, n-hexane fraction have the highest percentage of parasite elimination of 91.8% at 5000µg/ml lower than the standard anti-malarial drug (artemesinin combine treatment) with 92.8% at 5000µg/ml concentrations. Thus, it can be concluded that, further research on the plant may lead to the discovery of new potential anti-malarial drug in near future.

DOI 10.11648/j.bio.20160406.12
Published in American Journal of Bioscience and Bioengineering (Volume 4, Issue 6, December 2016)
Page(s) 65-69
Creative Commons

This is an Open Access article, distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution and reproduction in any medium or format, provided the original work is properly cited.

Copyright

Copyright © The Author(s), 2024. Published by Science Publishing Group

Keywords

Balsamodendron africanum, Anti-malaria, in vitro Bioassay, Phytochemical Screening

References
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[3] Saganuwan S. A. and Onyeyili P. A.: “Understanding of Malaria and Its Therapeutic Regimens–The Way Forward” International Journal of tropical disease & health 2014, 4(7): 802-840.
[4] Kheir, A. “Factors influencing evolution to antimalarial drug resistance in P. falciparum in Sudan and the Gambia”. Acta Universitatis Upsaliensis, Digital Comprehensive Summaries of Uppsala dissertations from the Faculty of Medicine 2011, 661:54.
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[18] Devo, A. A, Greary, T. G., Davis, N. L., and Jensen, J.B. “Nutritional requirements of P. falciparum in culture exogenously supplied with dialyzable components necessary for continuous growth”. J. Protozool. 1985, 32: 59–64.
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Author Information
  • Bioresources Development centre Katsina, National Biotechnology Development Agency, Abuja-Nigeria

  • Department of Chemistry, Bayero University Kano, Kano, Nigeria

  • Department of Chemistry, Umaru Musa Yar’adua University Katsina, Katsina, Nigeria

  • Bioresources Development centre Katsina, National Biotechnology Development Agency, Abuja-Nigeria

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    Abdurrahman Siraj Abubakar, Oumar Al-Mubarak Adoum, Yusuf Hassan, Bello Ibrahim. (2017). Phytochemical Screening and Anti-plasmodial Activity of Balsamodendron africanum (A. Rich) (Burseraceae). American Journal of Bioscience and Bioengineering, 4(6), 65-69. https://doi.org/10.11648/j.bio.20160406.12

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    Abdurrahman Siraj Abubakar; Oumar Al-Mubarak Adoum; Yusuf Hassan; Bello Ibrahim. Phytochemical Screening and Anti-plasmodial Activity of Balsamodendron africanum (A. Rich) (Burseraceae). Am. J. BioSci. Bioeng. 2017, 4(6), 65-69. doi: 10.11648/j.bio.20160406.12

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    AMA Style

    Abdurrahman Siraj Abubakar, Oumar Al-Mubarak Adoum, Yusuf Hassan, Bello Ibrahim. Phytochemical Screening and Anti-plasmodial Activity of Balsamodendron africanum (A. Rich) (Burseraceae). Am J BioSci Bioeng. 2017;4(6):65-69. doi: 10.11648/j.bio.20160406.12

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  • @article{10.11648/j.bio.20160406.12,
      author = {Abdurrahman Siraj Abubakar and Oumar Al-Mubarak Adoum and Yusuf Hassan and Bello Ibrahim},
      title = {Phytochemical Screening and Anti-plasmodial Activity of Balsamodendron africanum (A. Rich) (Burseraceae)},
      journal = {American Journal of Bioscience and Bioengineering},
      volume = {4},
      number = {6},
      pages = {65-69},
      doi = {10.11648/j.bio.20160406.12},
      url = {https://doi.org/10.11648/j.bio.20160406.12},
      eprint = {https://download.sciencepg.com/pdf/10.11648.j.bio.20160406.12},
      abstract = {Balsamodendron africanum was popularly known to be present within tropical Africa and some Indian regions. The stem bark extract of the plant was investigated for phytochemical screening and In vitro anti-malarial bioassay using n-hexane, chloroform, ethylacetate and methanol solvent fractions. The phytochemical screening revealed the presence of flavonoids, alkaloids, terpenoids, tannins, saponins anthraquinones and carbohydrates. The bioassay results showed that, n-hexane fraction have the highest percentage of parasite elimination of 91.8% at 5000µg/ml lower than the standard anti-malarial drug (artemesinin combine treatment) with 92.8% at 5000µg/ml concentrations. Thus, it can be concluded that, further research on the plant may lead to the discovery of new potential anti-malarial drug in near future.},
     year = {2017}
    }
    

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  • TY  - JOUR
    T1  - Phytochemical Screening and Anti-plasmodial Activity of Balsamodendron africanum (A. Rich) (Burseraceae)
    AU  - Abdurrahman Siraj Abubakar
    AU  - Oumar Al-Mubarak Adoum
    AU  - Yusuf Hassan
    AU  - Bello Ibrahim
    Y1  - 2017/01/16
    PY  - 2017
    N1  - https://doi.org/10.11648/j.bio.20160406.12
    DO  - 10.11648/j.bio.20160406.12
    T2  - American Journal of Bioscience and Bioengineering
    JF  - American Journal of Bioscience and Bioengineering
    JO  - American Journal of Bioscience and Bioengineering
    SP  - 65
    EP  - 69
    PB  - Science Publishing Group
    SN  - 2328-5893
    UR  - https://doi.org/10.11648/j.bio.20160406.12
    AB  - Balsamodendron africanum was popularly known to be present within tropical Africa and some Indian regions. The stem bark extract of the plant was investigated for phytochemical screening and In vitro anti-malarial bioassay using n-hexane, chloroform, ethylacetate and methanol solvent fractions. The phytochemical screening revealed the presence of flavonoids, alkaloids, terpenoids, tannins, saponins anthraquinones and carbohydrates. The bioassay results showed that, n-hexane fraction have the highest percentage of parasite elimination of 91.8% at 5000µg/ml lower than the standard anti-malarial drug (artemesinin combine treatment) with 92.8% at 5000µg/ml concentrations. Thus, it can be concluded that, further research on the plant may lead to the discovery of new potential anti-malarial drug in near future.
    VL  - 4
    IS  - 6
    ER  - 

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