Phytochemical Screening and Anti-plasmodial Activity of Balsamodendron africanum (A. Rich) (Burseraceae)
American Journal of Bioscience and Bioengineering
Volume 4, Issue 6, December 2016, Pages: 65-69
Received: Sep. 19, 2016; Accepted: Oct. 17, 2016; Published: Jan. 16, 2017
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Authors
Abdurrahman Siraj Abubakar, Bioresources Development centre Katsina, National Biotechnology Development Agency, Abuja-Nigeria
Oumar Al-Mubarak Adoum, Department of Chemistry, Bayero University Kano, Kano, Nigeria
Yusuf Hassan, Department of Chemistry, Umaru Musa Yar’adua University Katsina, Katsina, Nigeria
Bello Ibrahim, Bioresources Development centre Katsina, National Biotechnology Development Agency, Abuja-Nigeria
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Abstract
Balsamodendron africanum was popularly known to be present within tropical Africa and some Indian regions. The stem bark extract of the plant was investigated for phytochemical screening and In vitro anti-malarial bioassay using n-hexane, chloroform, ethylacetate and methanol solvent fractions. The phytochemical screening revealed the presence of flavonoids, alkaloids, terpenoids, tannins, saponins anthraquinones and carbohydrates. The bioassay results showed that, n-hexane fraction have the highest percentage of parasite elimination of 91.8% at 5000µg/ml lower than the standard anti-malarial drug (artemesinin combine treatment) with 92.8% at 5000µg/ml concentrations. Thus, it can be concluded that, further research on the plant may lead to the discovery of new potential anti-malarial drug in near future.
Keywords
Balsamodendron africanum, Anti-malaria, in vitro Bioassay, Phytochemical Screening
To cite this article
Abdurrahman Siraj Abubakar, Oumar Al-Mubarak Adoum, Yusuf Hassan, Bello Ibrahim, Phytochemical Screening and Anti-plasmodial Activity of Balsamodendron africanum (A. Rich) (Burseraceae), American Journal of Bioscience and Bioengineering. Vol. 4, No. 6, 2016, pp. 65-69. doi: 10.11648/j.bio.20160406.12
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Copyright © 2016 Authors retain the copyright of this article.
This article is an open access article distributed under the Creative Commons Attribution License (http://creativecommons.org/licenses/by/4.0/) which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
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