Multiple Drug Resistance and ESBL Production in Bacterial Urine Culture Isolates

Riffat Iqbal; Abdul Majid; Iqbal Ahmad Alvi; Azam Hayat; Farah Andalee; Saira Gul; Sabeena Irfan; Mujaddad Ur Rahman

doi:doi:10.11648/j.ajbio.20140201.12

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Multiple Drug Resistance and ESBL Production in Bacterial Urine Culture Isolates

Riffat Iqbal, Abdul Majid, Iqbal Ahmad Alvi, Azam Hayat, Farah Andalee, Saira Gul, Sabeena Irfan, Mujaddad Ur Rahman

Published in American Journal of BioScience (Volume 2, Issue 1)

Received: 7 December 2013 Accepted: Published: 30 December 2013

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Abstract

Transmission of bacterial strains between patients is a serious problem in hospitals and with the increasing rate of antibiotic resistance the problem has farther escalated. Enterobacteriaceae produced ESBLs, especially E-coli, are increasingly important nosocomial pathogens. These bacteria are often multiple resistant and are responsible for many intestinal infections and urinary tract infections. Urine samples [4010] were collected cultured and the bacterial isolates were identified in this study, 1000 isolates showed significant bacterial growth. Among the sample 1000 showed bacterial growth in which E.coli strains was most common 58.5% of the 1000 bacterial isolates from urine cultures, gram negative rods accounted for 95.30 %, while gram positive cocci accounted for the test 4.70 %. Total pathogen isolated and recovered is distributed as K. pneumoniae 16.7 %, Enterobacter spp 0.57 %, P. aeruginosa 14.5 %, Proteus spp 1.34 % Enterococci 1.05 %, S. aurus 0.76 % and E. faecalis 2.87 %, A. calcoaceticus 1.05 %, Enterobacter spp 0.57 % E. agglumarance 2.20 % serratia 0.1 %. In case of g negative bacteria 58 [2.45 %] were ESBL producers and 379 [47.54 %] were MDR. while in case of gram positive 2 [0.2 %] were MRSA. Resistance has arisen to all antibiotics introduced into general clinical practice and is likely to arise to any new antibiotics introduced in the future. It is therefore imperative to consider what can be done to minimize the development and transfer of antibiotics resistance gene clusters. Methods can be developed to minimize antibiotic resistance.

Published in	American Journal of BioScience (Volume 2, Issue 1)
DOI	10.11648/j.ajbio.20140201.12
Page(s)	5-12
Creative Commons	This is an Open Access article, distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution and reproduction in any medium or format, provided the original work is properly cited.
Copyright	Copyright © The Author(s), 2024. Published by Science Publishing Group

Keywords

MDR, ESBL, Bacteria, UTI

References

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APA Style

Riffat Iqbal, Abdul Majid, Iqbal Ahmad Alvi, Azam Hayat, Farah Andalee, et al. (2013). Multiple Drug Resistance and ESBL Production in Bacterial Urine Culture Isolates. American Journal of BioScience, 2(1), 5-12. https://doi.org/10.11648/j.ajbio.20140201.12

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ACS Style

Riffat Iqbal; Abdul Majid; Iqbal Ahmad Alvi; Azam Hayat; Farah Andalee, et al. Multiple Drug Resistance and ESBL Production in Bacterial Urine Culture Isolates. Am. J. BioScience 2013, 2(1), 5-12. doi: 10.11648/j.ajbio.20140201.12

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AMA Style

Riffat Iqbal, Abdul Majid, Iqbal Ahmad Alvi, Azam Hayat, Farah Andalee, et al. Multiple Drug Resistance and ESBL Production in Bacterial Urine Culture Isolates. Am J BioScience. 2013;2(1):5-12. doi: 10.11648/j.ajbio.20140201.12

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@article{10.11648/j.ajbio.20140201.12,
  author = {Riffat Iqbal and Abdul Majid and Iqbal Ahmad Alvi and Azam Hayat and Farah Andalee and Saira Gul and Sabeena Irfan and Mujaddad Ur Rahman},
  title = {Multiple Drug Resistance and ESBL Production in Bacterial Urine Culture Isolates},
  journal = {American Journal of BioScience},
  volume = {2},
  number = {1},
  pages = {5-12},
  doi = {10.11648/j.ajbio.20140201.12},
  url = {https://doi.org/10.11648/j.ajbio.20140201.12},
  eprint = {https://article.sciencepublishinggroup.com/pdf/10.11648.j.ajbio.20140201.12},
  abstract = {Transmission of bacterial strains between patients is a serious problem in hospitals and with the increasing rate of antibiotic resistance the problem has farther escalated. Enterobacteriaceae produced ESBLs, especially E-coli, are increasingly important nosocomial pathogens. These bacteria are often multiple resistant and are responsible for many intestinal infections and urinary tract infections. Urine samples [4010] were collected cultured and the bacterial isolates were identified in this study, 1000 isolates showed significant bacterial growth. Among the sample 1000 showed bacterial growth in which E.coli strains was most common 58.5% of the 1000  bacterial isolates from urine cultures, gram negative rods accounted for 95.30 %, while gram positive cocci accounted for the  test 4.70 %. Total pathogen isolated and recovered is distributed as K. pneumoniae 16.7 %,  Enterobacter spp 0.57 %, P. aeruginosa 14.5 %, Proteus spp 1.34 % Enterococci 1.05 %, S. aurus 0.76 % and E. faecalis 2.87 %, A. calcoaceticus 1.05 %, Enterobacter spp 0.57 % E. agglumarance 2.20 % serratia  0.1 %. In case of g negative bacteria 58 [2.45 %] were ESBL producers and 379 [47.54 %] were MDR. while in case of gram positive 2 [0.2 %] were MRSA. Resistance has arisen to all antibiotics introduced into general clinical practice and is likely to arise to any new antibiotics introduced in the future. It is therefore imperative to consider what can be done to minimize the development and transfer of antibiotics resistance gene clusters. Methods can be developed to minimize antibiotic resistance.},
 year = {2013}
}

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TY - JOUR
T1 - Multiple Drug Resistance and ESBL Production in Bacterial Urine Culture Isolates
AU - Riffat Iqbal
AU - Abdul Majid
AU - Iqbal Ahmad Alvi
AU - Azam Hayat
AU - Farah Andalee
AU - Saira Gul
AU - Sabeena Irfan
AU - Mujaddad Ur Rahman
Y1 - 2013/12/30
PY - 2013
N1 - https://doi.org/10.11648/j.ajbio.20140201.12
DO - 10.11648/j.ajbio.20140201.12
T2 - American Journal of BioScience
JF - American Journal of BioScience
JO - American Journal of BioScience
SP - 5
EP - 12
PB - Science Publishing Group
SN - 2330-0167
UR - https://doi.org/10.11648/j.ajbio.20140201.12
AB - Transmission of bacterial strains between patients is a serious problem in hospitals and with the increasing rate of antibiotic resistance the problem has farther escalated. Enterobacteriaceae produced ESBLs, especially E-coli, are increasingly important nosocomial pathogens. These bacteria are often multiple resistant and are responsible for many intestinal infections and urinary tract infections. Urine samples [4010] were collected cultured and the bacterial isolates were identified in this study, 1000 isolates showed significant bacterial growth. Among the sample 1000 showed bacterial growth in which E.coli strains was most common 58.5% of the 1000 bacterial isolates from urine cultures, gram negative rods accounted for 95.30 %, while gram positive cocci accounted for the test 4.70 %. Total pathogen isolated and recovered is distributed as K. pneumoniae 16.7 %, Enterobacter spp 0.57 %, P. aeruginosa 14.5 %, Proteus spp 1.34 % Enterococci 1.05 %, S. aurus 0.76 % and E. faecalis 2.87 %, A. calcoaceticus 1.05 %, Enterobacter spp 0.57 % E. agglumarance 2.20 % serratia 0.1 %. In case of g negative bacteria 58 [2.45 %] were ESBL producers and 379 [47.54 %] were MDR. while in case of gram positive 2 [0.2 %] were MRSA. Resistance has arisen to all antibiotics introduced into general clinical practice and is likely to arise to any new antibiotics introduced in the future. It is therefore imperative to consider what can be done to minimize the development and transfer of antibiotics resistance gene clusters. Methods can be developed to minimize antibiotic resistance.
VL - 2
IS - 1
ER -

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Author Information

Riffat Iqbal

Department of Microbiology, Hazara University, Mansehra Pakistan 21300
Abdul Majid

Department of Microbiology, Hazara University, Mansehra Pakistan 21300
Iqbal Ahmad Alvi

Department of Microbiology, Hazara University, Mansehra Pakistan 21300
Azam Hayat

Department of Microbiology, Hazara University, Mansehra Pakistan 21300
Farah Andalee

Department of Microbiology, Hazara University, Mansehra Pakistan 21300
Saira Gul

Department of Microbiology, Hazara University, Mansehra Pakistan 21300
Sabeena Irfan

Department of Microbiology, Hazara University, Mansehra Pakistan 21300
Mujaddad Ur Rahman

Department of Microbiology, Hazara University, Mansehra Pakistan 21300

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APA Style

Riffat Iqbal, Abdul Majid, Iqbal Ahmad Alvi, Azam Hayat, Farah Andalee, et al. (2013). Multiple Drug Resistance and ESBL Production in Bacterial Urine Culture Isolates. American Journal of BioScience, 2(1), 5-12. https://doi.org/10.11648/j.ajbio.20140201.12

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ACS Style

Riffat Iqbal; Abdul Majid; Iqbal Ahmad Alvi; Azam Hayat; Farah Andalee, et al. Multiple Drug Resistance and ESBL Production in Bacterial Urine Culture Isolates. Am. J. BioScience 2013, 2(1), 5-12. doi: 10.11648/j.ajbio.20140201.12

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AMA Style

Riffat Iqbal, Abdul Majid, Iqbal Ahmad Alvi, Azam Hayat, Farah Andalee, et al. Multiple Drug Resistance and ESBL Production in Bacterial Urine Culture Isolates. Am J BioScience. 2013;2(1):5-12. doi: 10.11648/j.ajbio.20140201.12

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@article{10.11648/j.ajbio.20140201.12,
  author = {Riffat Iqbal and Abdul Majid and Iqbal Ahmad Alvi and Azam Hayat and Farah Andalee and Saira Gul and Sabeena Irfan and Mujaddad Ur Rahman},
  title = {Multiple Drug Resistance and ESBL Production in Bacterial Urine Culture Isolates},
  journal = {American Journal of BioScience},
  volume = {2},
  number = {1},
  pages = {5-12},
  doi = {10.11648/j.ajbio.20140201.12},
  url = {https://doi.org/10.11648/j.ajbio.20140201.12},
  eprint = {https://article.sciencepublishinggroup.com/pdf/10.11648.j.ajbio.20140201.12},
  abstract = {Transmission of bacterial strains between patients is a serious problem in hospitals and with the increasing rate of antibiotic resistance the problem has farther escalated. Enterobacteriaceae produced ESBLs, especially E-coli, are increasingly important nosocomial pathogens. These bacteria are often multiple resistant and are responsible for many intestinal infections and urinary tract infections. Urine samples [4010] were collected cultured and the bacterial isolates were identified in this study, 1000 isolates showed significant bacterial growth. Among the sample 1000 showed bacterial growth in which E.coli strains was most common 58.5% of the 1000  bacterial isolates from urine cultures, gram negative rods accounted for 95.30 %, while gram positive cocci accounted for the  test 4.70 %. Total pathogen isolated and recovered is distributed as K. pneumoniae 16.7 %,  Enterobacter spp 0.57 %, P. aeruginosa 14.5 %, Proteus spp 1.34 % Enterococci 1.05 %, S. aurus 0.76 % and E. faecalis 2.87 %, A. calcoaceticus 1.05 %, Enterobacter spp 0.57 % E. agglumarance 2.20 % serratia  0.1 %. In case of g negative bacteria 58 [2.45 %] were ESBL producers and 379 [47.54 %] were MDR. while in case of gram positive 2 [0.2 %] were MRSA. Resistance has arisen to all antibiotics introduced into general clinical practice and is likely to arise to any new antibiotics introduced in the future. It is therefore imperative to consider what can be done to minimize the development and transfer of antibiotics resistance gene clusters. Methods can be developed to minimize antibiotic resistance.},
 year = {2013}
}

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