Methodology of Study of an Antihyperglycemic Traditional Cure with Oral Glucose Tolerance Test to Wistar Rat
American Journal of BioScience
Volume 4, Issue 2, March 2016, Pages: 16-19
Received: Feb. 1, 2016; Accepted: Mar. 18, 2016; Published: May 3, 2016
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Monteomo Gnate François, Laboratory of Biochemistry, UFR-Med. Sciences, University Felix Houphouēt-Boigny, Abidjan, Côte d’Ivoire
Koffi Dago Pierre, Endocrinology and Diabetology Service, CHU-Yopougon-Abidjan, Abidjan, Côte d’Ivoire
Atto Virginie, Laboratory of Animal Physiology, UFR-Biosciences-University Felix Houphouēt-Boigny, Abidjan, Côte d’Ivoire
Deh Zhou Patricia, Laboratory of Embryol-Cytol-Cytogen UFR-Med. Sciences-Univ F Houphouēt-Boigny, Abidjan, Côte d’Ivoire
Yapi Ahoua, Laboratory of Animal Biology, UFR-Biosciences-University Felix Houphouēt-Boigny, Abidjan, Côte d’Ivoire
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Our aim was to expose a method of study an antihyperglycemic traditional cure with oral glucose tolerance test to wistar rat. This methodology began by obtaining plants species component the cure, their extraction and identification of assets. The traditional cure is composited of leaves of both Heliotropium indicum (Borraginaceae), Ocimum gratissimum (Lamiaceae) and barks of both Sclerocarya birrea, (Anacardiaceae), Khaya senegalensis (Meliaceae). After, experimental animal is chosen and the blood samples are made. The pharmacological criteria took into account the oral antidiabetic therapeutic as the glibenclamide. Then the glucose overload is absorbed by the animals after administration of the test cure in single or multiple outlets. The anhydrous glucose used to induce experimental diabetes is administered at a dose of 4 g/kg/vo. Finally, we carried out the blood glucose. The methodology of study of an antihyperglycemic traditional cure took account the protection of laboratory animals after experimentation.
Methodology, Traditional Cure, Oral Glucose, Wistar Rat
To cite this article
Monteomo Gnate François, Koffi Dago Pierre, Atto Virginie, Deh Zhou Patricia, Yapi Ahoua, Methodology of Study of an Antihyperglycemic Traditional Cure with Oral Glucose Tolerance Test to Wistar Rat, American Journal of BioScience. Vol. 4, No. 2, 2016, pp. 16-19. doi: 10.11648/j.ajbio.20160402.12
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