American Journal of BioScience

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Chemical Synthesis, Spectral Characterization and Antimicrobial Studies on Complexes of Ni(II), Cu(II) and Zn(II) with N, N-di (o-hydroxybenzenoylmethylene) Ethylenediamine

Received: 30 June 2014    Accepted: 14 July 2014    Published: 20 August 2014
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Abstract

The Schiff’s base ligands and their complexes with Ni(II), Cu(II) and Zn(II) were synthesized and characterized by elemental analysis molar conductivity, infrared and ultraviolet-visible spectroscopy and magnetic susceptibility measurements. The ligands, ethylenedianil of o-hydroxyphenylglyoxal, C18H16N2O4, have been synthesized by condensation of ethylenediamine and orthohydroxyphenylglyoxal. The metal complexes were prepared by mixing of saturated solutions of ligands and metal salts in appropriate molar ratio in acetone and methanol solvents. The study also confirmed the formation of mono-, di- and trinuclear isopolystructures of the complexes in square planar geometry except for Zn(II), which has tetrahedral stereochemistry. The synthesized ligands and their metal complexes were screened for their antimicrobial activities against two bacterial strains (Staphylococcus aureous and Xanthomonas holcicola), and two fungal strains (Aspergillus niger and Fusarium oxysporum) using a disc diffusion method. The tests showed that the complexes have higher antimicrobial activity than the free Schiff’s base.

DOI 10.11648/j.ajbio.s.2014020601.15
Published in American Journal of BioScience (Volume 2, Issue 6-1, November 2014)

This article belongs to the Special Issue Chemical Biology

Page(s) 22-34
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This is an Open Access article, distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution and reproduction in any medium or format, provided the original work is properly cited.

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Copyright © The Author(s), 2024. Published by Science Publishing Group

Keywords

Antimicrobial Studies, Disc Diffusion Method, Ethylenedianil of O-Hydroxyphenyl Glyoxal, Ortho-Hydroxyphenylglyoxal, Schiff’s Base, N,N-di (o-hydroxybenzenoylmethylene) ethylenediamine

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  • Department of Chemistry, College of Natural Sciences, Arba Minch University, Ethiopia

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    Ali Mohammed Yimer. (2014). Chemical Synthesis, Spectral Characterization and Antimicrobial Studies on Complexes of Ni(II), Cu(II) and Zn(II) with N, N-di (o-hydroxybenzenoylmethylene) Ethylenediamine. American Journal of BioScience, 2(6-1), 22-34. https://doi.org/10.11648/j.ajbio.s.2014020601.15

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    Ali Mohammed Yimer. Chemical Synthesis, Spectral Characterization and Antimicrobial Studies on Complexes of Ni(II), Cu(II) and Zn(II) with N, N-di (o-hydroxybenzenoylmethylene) Ethylenediamine. Am. J. BioScience 2014, 2(6-1), 22-34. doi: 10.11648/j.ajbio.s.2014020601.15

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    Ali Mohammed Yimer. Chemical Synthesis, Spectral Characterization and Antimicrobial Studies on Complexes of Ni(II), Cu(II) and Zn(II) with N, N-di (o-hydroxybenzenoylmethylene) Ethylenediamine. Am J BioScience. 2014;2(6-1):22-34. doi: 10.11648/j.ajbio.s.2014020601.15

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  • @article{10.11648/j.ajbio.s.2014020601.15,
      author = {Ali Mohammed Yimer},
      title = {Chemical Synthesis, Spectral Characterization and Antimicrobial Studies on Complexes of Ni(II), Cu(II) and Zn(II) with N, N-di (o-hydroxybenzenoylmethylene) Ethylenediamine},
      journal = {American Journal of BioScience},
      volume = {2},
      number = {6-1},
      pages = {22-34},
      doi = {10.11648/j.ajbio.s.2014020601.15},
      url = {https://doi.org/10.11648/j.ajbio.s.2014020601.15},
      eprint = {https://download.sciencepg.com/pdf/10.11648.j.ajbio.s.2014020601.15},
      abstract = {The Schiff’s base ligands and their complexes with Ni(II), Cu(II) and Zn(II) were synthesized and characterized by elemental analysis molar conductivity, infrared and ultraviolet-visible spectroscopy and magnetic susceptibility measurements. The ligands, ethylenedianil of o-hydroxyphenylglyoxal, C18H16N2O4, have been synthesized by condensation of ethylenediamine and orthohydroxyphenylglyoxal. The metal complexes were prepared by mixing of saturated solutions of ligands and metal salts in appropriate molar ratio in acetone and methanol solvents. The study also confirmed the formation of mono-, di- and trinuclear isopolystructures of the complexes in square planar geometry except for Zn(II), which has tetrahedral stereochemistry. The synthesized ligands and their metal complexes were screened for their antimicrobial activities against two bacterial strains (Staphylococcus aureous and Xanthomonas holcicola), and two fungal strains (Aspergillus niger and Fusarium oxysporum) using a disc diffusion method. The tests showed that the complexes have higher antimicrobial activity than the free Schiff’s base.},
     year = {2014}
    }
    

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  • TY  - JOUR
    T1  - Chemical Synthesis, Spectral Characterization and Antimicrobial Studies on Complexes of Ni(II), Cu(II) and Zn(II) with N, N-di (o-hydroxybenzenoylmethylene) Ethylenediamine
    AU  - Ali Mohammed Yimer
    Y1  - 2014/08/20
    PY  - 2014
    N1  - https://doi.org/10.11648/j.ajbio.s.2014020601.15
    DO  - 10.11648/j.ajbio.s.2014020601.15
    T2  - American Journal of BioScience
    JF  - American Journal of BioScience
    JO  - American Journal of BioScience
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    PB  - Science Publishing Group
    SN  - 2330-0167
    UR  - https://doi.org/10.11648/j.ajbio.s.2014020601.15
    AB  - The Schiff’s base ligands and their complexes with Ni(II), Cu(II) and Zn(II) were synthesized and characterized by elemental analysis molar conductivity, infrared and ultraviolet-visible spectroscopy and magnetic susceptibility measurements. The ligands, ethylenedianil of o-hydroxyphenylglyoxal, C18H16N2O4, have been synthesized by condensation of ethylenediamine and orthohydroxyphenylglyoxal. The metal complexes were prepared by mixing of saturated solutions of ligands and metal salts in appropriate molar ratio in acetone and methanol solvents. The study also confirmed the formation of mono-, di- and trinuclear isopolystructures of the complexes in square planar geometry except for Zn(II), which has tetrahedral stereochemistry. The synthesized ligands and their metal complexes were screened for their antimicrobial activities against two bacterial strains (Staphylococcus aureous and Xanthomonas holcicola), and two fungal strains (Aspergillus niger and Fusarium oxysporum) using a disc diffusion method. The tests showed that the complexes have higher antimicrobial activity than the free Schiff’s base.
    VL  - 2
    IS  - 6-1
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