Particle Focusing in Microchannel with Multi-Parallel Channels or Porous Orifice
International Journal of Mechanical Engineering and Applications
Volume 6, Issue 3, June 2018, Pages: 46-54
Received: Apr. 22, 2018; Accepted: May 7, 2018; Published: May 28, 2018
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Authors
Hiroshige Kumamaru, Department of Mechanical Engineering, University of Hyogo, Himeji, Japan
Hirofumi Sugami, Department of Mechanical Engineering, University of Hyogo, Himeji, Japan
Masaki Nakahira, Department of Mechanical and System Engineering, University of Hyogo, Himeji, Japan
Naohisa Takagaki, Department of Mechanical Engineering, University of Hyogo, Himeji, Japan
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Abstract
The sheathless particle focusing in a microchannel installing one set of multi-parallel channels or one porous orifice is proposed in this study. Numerical calculations have been carried out by the Lagrange two-phase model (i.e. the particle tracking model) in PHOENICS software for the microchannel including the porous orifice, in simulating both the channels installing the multi-parallel channels and the porous orifice. It becomes clear from calculation results that the particle focusing may be achieved at lower inlet velocities by using the porous orifice. Low velocities correspond to reduction in the sample flow including particles (i.e. cells). It also becomes obvious that the particle focusing is improved if the porous orifice with taper shape is used. Furthermore, particle focusing experiments have been conducted in the channel including the multi-parallel channels. It becomes clear that the particle focusing may be achieved by using the multi-parallel channels.
Keywords
Particle Focusing, Microchannel, Multi-Parallel Channels, Porous Orifice
To cite this article
Hiroshige Kumamaru, Hirofumi Sugami, Masaki Nakahira, Naohisa Takagaki, Particle Focusing in Microchannel with Multi-Parallel Channels or Porous Orifice, International Journal of Mechanical Engineering and Applications. Vol. 6, No. 3, 2018, pp. 46-54. doi: 10.11648/j.ijmea.20180603.11
Copyright
Copyright © 2018 Authors retain the copyright of this article.
This article is an open access article distributed under the Creative Commons Attribution License (http://creativecommons.org/licenses/by/4.0/) which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
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